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Neurodegenerative Equipment Supplied In Europe
27 equipment items found
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
mGlu3 PAM for the treatment of neurodegenerative disorders. We are developing mGlu3 PAM as a novel orally available treatment for neurodegenerative disorders. We are currently optimizing multiple chemical series of highly selective mGlu3 PAMs, with compounds in early lead optimization. ...
Manufactured by:BioArctic AB based inStockholm, SWEDEN
Research to develop new antibodies for treating neurodegenerative disorders is under way at BioArctic. the ND3014 project aims to develop selective antibody treatments targeting TDP-43, a protein that is believed to play a crucial role in the development of the rare neurodegenerative disease ALS (amyotrophic lateral ...
Manufactured by:betaSENSE based in, GERMANY
betaSENSE has developed a cutting-edge platform technology leveraging the principles of infrared spectroscopy to advance diagnostics in neurodegenerative disorders. The technology, known as betaSENSE, utilizes differential spectroscopy to detect minute changes between states of a sample by subtracting absorption spectra, thereby highlighting protein signals such as amyloid-beta ...
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Manufactured by:Bertin Technologies based inMontigny-le-Bretonneux, FRANCE
Bertin Bioreagent offers primary and secondary antibodies for laboratories. As essential tools, they are particularly versatile when properly ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Protein misfolding is the root of many diseases, including lysosomal storage disorders and neurodegenerative ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Parkinson’s disease is a neurodegenerative disorder that affects more than 6 million people worldwide. In most cases, the exact cause of Parkinson’s disease is unknown; however, mutations in GBA1, the gene that encodes the beta-glucocerebrosidase (GCase) enzyme, have been tied to the disease. ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Krabbe disease is a severe neurodegenerative disorder caused by mutations in GALC, the gene that encodes the galactosylceramidase (GALC) enzyme. These mutations cause GALC misfolding and dysfunction, which leads to the toxic buildup up fats in the central nervous system (CNS) and ultimately leads to the demyelination and death of neurons. ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Cortical neurons play a vital role in many neurodegenerative diseases, including Alzheimer’s disease. Human iPSC-derived cortical neurons can be co-cultured with astrocytes and microglia to model neurodegenerative diseases. Our team can manufacture cortical neurons at scale from the iPSC line that best fits your project or work with off-the-shelf Ncyte ...
Manufactured by:Gogoa Mobility Robots based inTraña-Matiena (Bizkaia), SPAIN
HANK is a lower limb exoskeleton for rehabilitation of patients with spinal cord injury, neurodegenerative diseases or have suffered cerebrovascular accidents (stroke). This solution is made up of 6 motorized joints that allow functional recovery of gait and personal ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Disturbances in calcium signaling are associated with many neurodegenerative diseases and cardiomyopathies. Fluorescence-based assays with iPSC-derived cardiac and neuronal models can be used to monitor short and long-term drug-induced changes on calcium transients. Our scientists develop the most optimal calcium transient assay for each project and can scale it up for ...
Manufactured by:ReGen Therapeutics Limited based inLondon, UNITED KINGDOM
ReGen Therapeutics was formed in February 1998 to develop Colostrinin™, a proline-rich polypeptide complex derived from mammalian colostrum. The complex and the peptides within it are viewed as having potential utility in neurodegenerative illnesses such as Alzheimer’s disease, Parkinson’s Disease, Multiple Sclerosis and Amyotrophic Lateral ...
by:Numares GROUP Corp based inRegensburg, GERMANY
The first step in diagnosing the disease involves a careful study of a patient’s medical history combined with a thorough physical and neurologic examination, while ruling out other possible causes of neurodegenerative symptoms. ...
Manufactured by:Valtronic Technologies (Suisse) SA based inLes Charbonnieres, SWITZERLAND
Deep brain stimulation (DBS) implant surgery has been found to give great improvement in motor function and to reduce symptoms of neurodegenerative diseases such as Parkinson’s. Our customer designed a directional stimulation probe which allows for targeted and controlled deep brain treatment. ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. ...
Manufactured by:Firalis Group based inHuningue, FRANCE
NEUROLINCS : A non-invasive in-vitro diagnostic test measuring 7494 brain-enriched long non-coding RNAs (lncRNAs) that are specific to neurodegenerative ...
Manufactured by:BioArctic AB based inStockholm, SWEDEN
In Alzheimer’s disease soluble, toxic amyloid beta aggregates are believed to contribute to the neurodegenerative process. Lecanemab, a anti amyloid-beta protofibril antibody, selectively binds to these forms of amyloid beta and eliminates them. The antibody’s unique profile is highly selective for amyloid beta oligomers/protofibrils in the brain. ...
Manufactured by:BioArctic AB based inStockholm, SWEDEN
Our mission is to improve quality of life for patients suffering from Central Nervous System (CNS) disorders. Patients with neurodegenerative disorders like Alzheimer’s disease and Parkinson’s disease will be treated with antibodies targeting the misfolded proteins in these disorders. Our technology is now applied to other CNS disorders like Parkinson’s disease, ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
The PPI-FIT (Pharmacological Protein Inactivation by Folding Intermediate Targeting) technology, of which Sibylla is the exclusive licensee, is a paradigm shift in rational drug design. The basic task of drug design is to find a small molecule able to bind a biological target -such as a protein- so to modulate or block its activity. So far, almost all drug design has focused on the native ...
Manufactured by:VECT-HORUS based inMARSEILLE, FRANCE
Vect-Horus has developed its “VECTrans®” breakthrough technology platform with the objective of making the ‘undruggable’ druggable by overcoming challenges of the BBB, and more generally biological barriers. VECTrans® is based on the specific design and optimization of ‘molecular vectors’ that, once conjugated to a payload, enable its delivery to target ...
by:Oxford Brain Diagnostics Ltd. based inOxford, UNITED KINGDOM
Using CDM® we will optimise patient selection, combine other clinical and patient demographics, and positively impact trial costs and performance. CDM® can estimate a patient’s pathology disease stage using grey matter quality. We provide a likelihood that a patient will progress to the next stage of disease within the next few years. ...