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Aptamer Equipment Supplied In North America
11 equipment items found
by:AptaMatrix, Inc. based inSyracuse, NEW YORK (USA)
Aptamers are DNA/RNA molecules that have affinities for their targets similar to antibodies. Aptamers have shown great potential to replace antibodies in biosensors, point-of-care diagnostics, therapeutics, and all of the areas currently dominated by antibodies. Once aptamers have been identified, they can be produced for less than 10% of the ...
by:Alfa Cytology based inU.S. VIRGIN ISLANDS
P12FR2 aptamer sodium is a 2'-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. The P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in a wound healing assay and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer ...
Manufactured by:Qualigen Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
QN-247, formerly referred to as ALAN (Aptamer Linked Anti Nucleolin), is an aptamer-based investigational drug candidate currently under development and evaluation with the potential to treat a variety of different cancer types, including liquid and solid tumors. A key component of this drug candidate, the QN-165 aptamer, has been tested in over ...
by:Base Pair Biotechnologies, Inc. based inPearland, TEXAS (USA)
The determination of aptamer-target binding characteristics is an important tool in the aptamer discovery process. Affinity determination with Bio-Layer Interferometry (BLI) can be used to select aptamer candidates for specific downstream applications, identify matched aptamer pairs, and optimize buffer formulations. BLI is ...
Manufactured by:LifeTein, LLC based inHillsborough, NEW JERSEY (USA)
The beads are used to covalently conjugate primary amine or carboxy-containing ligands. The beads are used to couple amine-containing ligands such as DNA/RNA, peptides, proteins, antibodies, and aptamers. Subsequently, target proteins are easily separated from the solution using a magnet for downstream ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. ...
by:BellBrook Labs based inMadison, WISCONSIN (USA)
AptaFluor SAH Methyltransferase Assay directly measures SAH produced by methyltransferase enzymes during methylation. These enzymes methylate a variety of substrates using S-adenosylmethionine (SAM) as the methyl donor, leaving the common product S-adenosylhomocysteine (SAH). These SAH measurements allow researchers to effectively determine the activity of the methyltransferase enzyme. The ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Utilizing our proprietary Sword Swift™ Method Development Process and Sword Swift™ Detection Reagents, our scientists can develop sensitive quantitative assays to measure the amounts of free or bound drug in preclinical or clinical samples with high accuracy and ...
Manufactured by:RayBiotech Life, Inc. based inPeachtree Corners, GEORGIA (US) (USA)
The Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4) Epitope Mapping Peptide Array is a semi-quantitative array displaying 177 synthesized peptides representing the full-length CTLA4. It is suitable for antibody epitope mapping and detection of IgG, IgA, IgM, IgE, etc. in serum, plasma, and many other liquid sample types. ...
Manufactured by:Manzanita Pharmaceuticals, Inc. based inWoodside, CALIFORNIA (USA)
Nervelight™, a topical, intraoperative nerve imaging agent that is selective for at-risk nerve tissue in cancer ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell ...