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Neurodegeneration Disease Equipment Supplied In North America
66 equipment items found
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Manufactured by:Bertin Technologies based inMontigny-le-Bretonneux, FRANCE
Bertin Bioreagent offers primary and secondary antibodies for laboratories. As essential tools, they are particularly versatile when properly ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Protein misfolding is the root of many diseases, including lysosomal storage disorders and neurodegenerative ...
by:LIXTE Biotechnology Holdings, Inc. based inPasadena, CALIFORNIA (USA)
We have also developed another class of compounds that are novel histone deacetylase inhibitors (HDACi). Designated as our LB-200 series of compounds, these have potential use in the prevention and treatment of neurodegenerative diseases. The series has the potential to be the most effective in its class and may be useful for the treatment of chronic hereditary diseases, such as Gaucher’s ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 24 months (Avoid repeated freeze / thaw cycles.) Background (Function): 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3- 3 family members interact with a wide spectrum of proteins and possess diverse ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 24 months (Avoid repeated freeze / thaw cycles.) Background (Function): 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3- 3 family members interact with a wide spectrum of proteins and possess diverse ...
Manufactured by:MuseChem based inPaoli, PENNSYLVANIA (USA)
Methylene Blue Trihydrate is a synthetic compound with diverse medical applications, known for its role as a redox agent and dye. It is used in the treatment of methemoglobinemia by restoring normal hemoglobin function, as well as in surgical procedures to visualize tissues. Methylene Blue also has antimicrobial properties, making it useful in treating infections. Additionally, it is studied for ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Alkahest, with its partner Grifols, is developing lead clinical candidates, GRF6019 and GRF6021, as potential treatments for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease with cognitive impairment. Designed to safely replenish regenerative positive chronokines that decrease with age, GRF6019 and GRF6021 are highly selected human plasma fractions that ...
Manufactured by:AVEO Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
AV-353 is the Company’s potent, selective, high affinity inhibitory antibody specific to Notch 3. The Notch 3 signaling pathway is important in cell-to-cell communication involving gene regulation mechanisms that control multiple cell differentiation processes during the entire life cycle. Scientific literature has implicated the Notch 3 receptor pathway in multiple diseases, including ...
Manufactured by:Bmseed based inMesa, ARIZONA (USA)
Mechanics Module for cell stretching to mimic in vivo biomechanics in a controlled in vitro ...
Manufactured by:Woolsey Pharmaceuticals, Inc. based inNew York City, NEW YORK (USA)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. ALS is part of a wider group of disorders known as motor neuron diseases. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body, governing voluntary movements and muscle control. ALS causes progressive ...
Manufactured by:Blackrock Neurotech based inSalt Lake City, UTAH (USA)
With its high-channel count, superior signal-to-noise ratio, and exceptional quality, the Utah Array powers the most ambitious neuroscience research. Utilizing the latest advancements in neurotechnology, its electrodes are capable of recording and stimulating individual neurons or groups of neurons with maximum ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Autophagy is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome. Autophagy plays a wide variety of physiological and pathophysiological roles. Different selective forms of autophagy have been identified and characterized, leading to the specific degradation of organelles or pathogens. These selective pathways include the autophagic degradation of ...
Manufactured by:Caprico Biotechnologies, Inc. (CBI) based inNorcross, GEORGIA (US) (USA)
EAPII (also called TTRAP, TDP2) originally was identified as an interacting partner of oncogene ETS1, a founding member of ets transcription factor, and the cytoplasmic domain of CD40, a member of the tumor necrosis factor (TNF) receptor family. EAPII significantly represses ETS1 transcriptional activity and the synergistic transactivation by ETS1 and AP-1 or by ETS1 and NFκB. EAPII/TTRAP ...
by:Vybion based inMonterey, CALIFORNIA (USA)
INT41 has received Orphan Drug Designation from the FDA for Huntington’s disease. IND enabling studies for INT41 Gene Therapy for Huntington’s disease are in place following a preIND meeting with the FDA in in February 2022 in response to the briefing book prepared by our consultants at Latham BioPharm, a world class consulting group based in Cambridge MA. ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
The Sleep Profiler PSG2 combines the accuracy and versatility of the Sleep Profiler with the cardio-respiratory signals needed for a Type 2 unattended, virtually wireless polysomnography study. The 13-channel system includes EEG, EOG and EMG, wireless oximetry, nasal pressure/airflow, chest and abdomen respiratory effort (RIP or piezo), forehead and finger pulse rate, head movement and position, ...
Manufactured by:Bmseed based inMesa, ARIZONA (USA)
Mechanics Module: strain rate up to 50/s, strain up to 50%. Imaging Module: frame rate: 2,000fps. Electrophysiology Module: 2x60 channels. Pathological stretch of cells to reproduce biomechanics of an injury such as traumatic brain injury (TBI) or spinal cord injury (SCI); assessment of cell health and function using electrophysiological measurements; visualization of cells and cellular ...
Manufactured by:Bmseed based inMesa, ARIZONA (USA)
Mechanics Module: strain rate up to 80/s, strain up to 50%. Imaging Module: frame rate: 2,000fps. Electrophysiology Module: 2x60 channels. Very rapid pathological stretch of cells to reproduce biomechanics of an injury such as traumatic brain injury (TBI) or spinal cord injury (SCI); assessment of cell health and function using electrophysiological measurements; visualization of cells and ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Protein aggregation is a major pathological feature of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD). Under pathological conditions, Tau, Amyloid beta, alpha-synuclein, TDP-43, Huntingtin and other proteins integrate into a wide array of undesirable structures, ranging from oligomers and ...
Manufactured by:Stem Pharm, Inc based inMadison, WISCONSIN (USA)
Stem Pharm’s advanced neural organoid models uniquely contain microglia and provide new opportunities to investigate CNS disease modeling, drug discovery, and toxicology applications. ...
Manufactured by:Lafayette Instrument Company based inLafayette, INDIANA (USA)
The Second Generation Bussey Chambers with Intelli-interface supports up to 20 chambers on one PC. On the strength of 10 years of feedback and development, the system is even more flexible and with more ...