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Cancer Cells Equipment Supplied In United Kingdom
47 equipment items found
Manufactured by:The Electrospinning Company Ltd. based inDidcot, UNITED KINGDOM
The thickness of Mimetix scaffold allows for having a 3D environment while maintaining a certain translucence, thus allowing for easy and robust imaging. This study has investigated the localisation depth of MCF7 breast cancer cells in the Mimetix scaffold after 4 days of culture (nuclei stained with TO-PRO-3, blue). The video below shows a Z-stack (slices ...
Manufactured by:The Electrospinning Company Ltd. based inDidcot, UNITED KINGDOM
Images taken using a Nikon Eclispe C1 confocal microscope. HepG2 liver cells were grown for 21 days in the Mimetix scaffold. Cells are stained with DAPI and actin; fibres are electrospun together with Rhodamine 6G (a and b). Cancer cells form a 3D network inside the scaffold (c), use the fibres to support themselves (d) and ...
Manufactured by:Biosceptre International Limited based inCambridge, UNITED KINGDOM
CAR T-cell therapy is the engineering of a patient’s T cells, a type of white blood cell. A small portion of these cells are collected, from a patient’s blood sample, and re-engineered to produce chimeric antigen receptors (CAR’s) on the cell surface. The chimeric antigen receptors give T ...
Manufactured by:Kinomica based inMacclesfield, UNITED KINGDOM
Kinomica have used KScan®, a much more accurate way to predict whether an Acute myeloid leukaemia patient will respond to midostaurin. KScan® involves measuring the simultaneous activity of kinases within a patient’s cancer cells. This readout can then better predict whether midostaurin will destroy those ...
Manufactured by:Oxford Vacmedix UK Limited based inOxford, UNITED KINGDOM
In the image below the Recombinant Overlapping Peptide is the “Antigen” being presented to the T Cell Receptor (TCR). This then triggers the growth of T Cells that will recognise the same marker on cancer cells leading to their destruction. ...
Manufactured by:Biosceptre International Limited based inCambridge, UNITED KINGDOM
When exposed to high concentrations of extracellular adenosine triphosphate (ATP), P2X7 forms a channel, driving a range of diverse physiological functions including proliferation and immune cell functions. Under prolonged stimulation, P2X7 can form a membrane pore that’s associated with induction of cell death. Additional published data reaffirms ...
Manufactured by:Blue Earth Diagnostics based inOxford, UNITED KINGDOM
Diagnostic nuclear medicine is a type of molecular imaging that uses very small amounts of radioisotopes attached to a targeting molecule (radiopharmaceutical1) to diagnose complex diseases such as cancer. Radiopharmaceuticals are able to show the physiological function of the body rather than just the anatomy. Changes in the biochemical activity of cells often ...
Manufactured by:Avelas Biosciences based inLa Jolla, CALIFORNIA (USA)
Pegloprastide (AVB-620) is based on the science of activatable cell-penetrating peptides and is designed to deliver a fluorescent marker specifically to cancer cells to enable surgeons to identify cancerous tissue in real-time and thus, avoid repeat surgeries and improve patient outcomes. Pegloprastide is the only ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Chemo-scale is an advanced non-invasive test which provides therapeutically relevant information and is based on a safe, simple, and quick blood draw. Chemo-scale™ investigates in vitro chemo-resistance in Circulating Tumor Associated Cells (CTACs) isolated from the blood sample. CTACs include cancer cells that escape from the tumor and ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Trublood is an advanced non-invasive blood test (which provides diagnostically relevant information about cancers via a safe, simple and quick blood draw). Trublood® evaluates blood sample to detect ‘Circulating Tumor Cells’ (CTCs), which are cancer cells that escape from the tumor and enter the blood stream. ...
Manufactured by:Datar Cancer Genetics based inGuildford, UNITED KINGDOM
Pinaka™ is an advanced non-invasive blood test which provides therapeutically relevant information via a safe, simple and quick blood draw. Pinaka™ evaluates blood sample to detect ‘Circulating Tumor Cells’ (CTCs), which are cancer cells that escape from the tumor and enter the blood stream. Pinaka™ enriches these ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
The vaccine is composed of a combination of three peptides from two target antigens that are commonly modified in cancer cells. The first is the cytoskeletal protein, vimentin, which is preferentially digested during autophagy. All mesenchymal tumours such as endometrial, renal, sarcomas, lymphomas and lung tumours express vimentin as their major cytoskeletal ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
Glycosylation is a post-translational modification that occurs inside the cell and results in the addition of sugar motifs, “glycans”, to proteins and lipids that are, in most cases, destined for the cell surface. These glycan structures form the “glycome” and play an integral role in cell-to-cell and ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Bortezomib (brand name: Velcade) is a treatment for multiple myeloma (a cancer of the plasma cells) and mantle cell lymphoma (a cancer of the lymph ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M10 (MAGE-A10) T-cell therapy is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. Any expression in cancer is often associated with higher grade tumors. Please note that the two trials with ADP-A2M10 are now closed for ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
B7-H3 expression has been detected in a wide range of solid tumors including lung, breast, colorectal, liver and skin cancers. It has also been observed on tumor vasculature and stroma, has been hypothesized to be an immune checkpoint and to be expressed on cancer stem cells, making it promising target for the treatment of metastatic disease. The ...
Manufactured by:Oxford Gene Technology IP Limited based inOxford, UNITED KINGDOM
The HER2 amplification probe consists of a 347kb probe labelled in red, spanning the HER2 (ERBB2) gene and neighbouring regions, and a green probe for the chromosome 17 ...
by:Biorbyt Ltd based inCambridge, UNITED KINGDOM
Monoclonal antibodies; one of the most widely used tools in biological research, with the potential soon to become important therapeutics, have been with us for just over 40 years. These antibodies are monovalent, bind to a single epitope and are produced by a single B-lymphocyte clone. The first monoclonal antibody was generated in mice in 1975 by Milstein and Kohler, using the hybridoma ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TC BioPharm’s cell banks have been developed as a resource for clinical development of cost-effective, safe and efficacious therapeutic treatments and ultimately, the ability to treat more patients. These T cell banks provide TC BioPharm with core technology to develop a deep portfolio of next-generation CAR-T products directed against a wide variety of ...