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Alzheimer S Equipment Supplied In Usa California
13 equipment items found
Manufactured by:Leucadia Therapeutics based inRiverside, CALIFORNIA (USA)
Cerebrospinal fluid (CSF) clears toxic metabolites from intercellular spaces in the brain, much as the lymphatic system does in the rest of the body. The first regions of the brain to be impacted by Alzheimer's disease are cleared by CSF that drains across a porous bone called the cribriform plate. Aging and life events can occlude the cribriform plate and reduce the CSF-mediated clearance of ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
mGlu2 NAM for the treatment of mild neurocognitive disorders, or mNCD. We are developing mGlu2 NAM as a novel orally available treatment for mNCD associated with Alzheimer’s disease, Parkinson’s disease and depressive disorders. The program is in clinical candidate selection phase and we expect to enter IND enabling studies early in ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 24 months (Avoid repeated freeze / thaw cycles.) Background (Function): 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3- 3 family members interact with a wide spectrum of proteins and possess diverse ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 24 months (Avoid repeated freeze / thaw cycles.) Background (Function): 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3- 3 family members interact with a wide spectrum of proteins and possess diverse ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Alkahest, with its partner Grifols, is developing lead clinical candidates, GRF6019 and GRF6021, as potential treatments for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease with cognitive impairment. Designed to safely replenish regenerative positive chronokines that decrease with age, GRF6019 and ...
by:Dorian Therapeutics based inSan Carlos, CALIFORNIA (USA)
During aging, there is a decrease in the activity of stem cells, and therefore a reduced regenerative capacity. Additionally, senescent cells accumulate in the body and poison entire tissues. Dorian’s Senoblockers act on epigenetic regulators to reverse both processes, reactivating programs of youthfulness and regeneration. ...
Manufactured by:Cell Technology based inDavis, CALIFORNIA (USA)
Acute toxicity to humans and animals through inhibition of AChE by both nerve gases and an important class of pesticides has long been a field of intensive scientific investigation 4,5. AChE inhibitors have also been used clinically as Alzheimer’s treatments (e.g., tacrine (tetrahydroaminoacridine)) 6 and are the subject of increasing interest in various ...
Manufactured by:Vala Sciences based inSan Diego, CALIFORNIA (USA)
By maintaining brain homeostasis, clearing cellular debris [3], pruning synapses [4], and eliminating protein aggregates [5], microglia play key roles in neurodevelopment [6], Alzheimer’s Disease [7], Parkinson’s Disease [8], ALS [9], traumatic brain injury [10], and many other central nervous system ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
One the key chronokine targets identified using Alkahest’s platform is eotaxin. Eotaxin is an immunomodulatory chemokine that is increased in normal aging as well as multiple diseases of aging. It has been implicated in Alzheimer’s disease, Parkinson’s disease, retinal diseases and other aging-related diseases ...
Manufactured by:Konan Medical USA, Inc. based inIrvine, CALIFORNIA (USA)
Checking pupils for an APD is an important part of the comprehensive eye exam, and is recommended in the AAO’s Preferred Practice Patterns for POAG suspects and patients, however the swinging flashlight method is difficult for humans to do well, and even more difficult and time consuming to accurately quantify. Importantly, there is evidence that subtle APDs may be clinically significant. ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Sleep Profiler™ EEG Sleep Monitor bridges the gap between laboratory polysomnography and actigraphy. Three frontopolar channels provide the EEG, EOG and EMG signal features needed to characterize by-stage sleep time. The lightweight, wireless device includes voice messages and other intuitive design features that enable reliable self-application in the home with acquisition across multiple ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
They have been implicated in many human neurodegenerative disorders such as multiple sclerosis, amyotrophic lateral sclerosis (ALS), Alzheimer’s disorder, Huntington’s disease and Parkinson’s disease. Tempo’s iAstro™: human iPSC-derived astrocytes are derived from integration-free ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
The barrier regulates the transport of molecular chemicals (including metabolites) and cells between the brain and blood. The barrier’s functionality is conducted via specialized groups of tight junction proteins and transporters. Found in diseases like Multiple Sclerosis, Alzheimer’s, Parkinson’s, Epilepsy, and ...