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Tumor Microenvironment Equipment Supplied In Usa California
18 equipment items found
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
The product profile of SENTI-301 has the potential to promote expansion and persistence of NK cells, and activate and recruit the body’s own immune cells into the solid tumor microenvironment for enhanced anti-tumor activity. ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
Probody therapeutics are designed to outsmart cancer by exploiting the unique conditions of the tumor microenvironment to more effectively localize treatment to the tumor, while limiting activity in healthy tissues. These novel therapies are designed to take advantage of high levels of protease activity in the tumor ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
OncoPeptTUME — A novel in-silico approach to model the tumor microenvironment and predict treatment efficacy and long-term survival benefits for immunotherapy applications. Cancer immunotherapy is now established as a major therapeutic modality. Cancer immunotherapy drugs elicit their anti-tumor immune response in a subset of the treated ...
by:Ionpath, Inc. based inMenlo Park, CALIFORNIA (USA)
L-arginine is a necessary metabolite for T cell receptor signaling and T cell proliferation. Arginase is induced by inflammation. In cancer, MDSCs within the tumor microenvironment (TME) produce arginase-1 resulting in low levels of available L-arginine within the TME leading to attenuated T cell ...
by:Caribou Biosciences, Inc. based inBerkeley, CALIFORNIA (USA)
Natural killer (NK) cells, as their name implies, play an important role in ridding the body of cancer and viruses. NK cells are emerging as an increasingly important cell type for therapeutic development. Solid tumors are particularly challenging to treat and CAR-T cells have largely underperformed in the solid tumor setting. NK cells, however, inherently ...
Manufactured by:Ibio, Inc. based inBryan, TEXAS (USA)
Advances in the field of immuno-oncology have led to new and better treatment outcomes for a range of cancers, and particularly, blood cancers. However, even with the advent of checkpoint inhibitors as immunotherapies for solid tumors, significant challenges remain. This is in part due to dynamics in the tumor microenvironment, wherein regulatory ...
![Ionpath - Model 164Dy - a-SMA [D4K9N] Antibody](https://d32zuqhgcrpxli.cloudfront.net/eyJidWNrZXQiOiJlZS1maWxlcyIsImtleSI6ImZpbGVzLzExOTg1Mi9wcm9kdWN0cy83OTY1NTkvMTE5ODUyXzJfMjAyMjA3MTYwNjUwNTU1MDE3NTc1X3Jhdy5wbmciLCJlZGl0cyI6eyJyZXNpemUiOnsiZml0IjoiY29udGFpbiIsImJhY2tncm91bmQiOnsiciI6MjU1LCJnIjoyNTUsImIiOjI1NSwiYWxwaGEiOjF9LCJ3aWR0aCI6MjQwLCJoZWlnaHQiOjE0NX19fQ== "Ionpath - Model 164Dy - a-SMA [D4K9N] Antibody")
by:Ionpath, Inc. based inMenlo Park, CALIFORNIA (USA)
Background:α-smooth muscle actin (α-SMA, ACTA2) is one of six actin isoforms found in vertebrates. α-SMA is expressed in a variety of tissues and is used as a marker of vascular smooth muscle, myofibroblasts, and cancer-associated fibroblasts (CAFs)lume: 100uL with a recommended usage of 1uL per 100 uL staining ...
Manufactured by:XILIS, Inc. based inDurham, NORTH CAROLINA (USA)
Xilis’ proprietary MicroOrganoSphere (MOS) technology represents a new standard in patient-derived micro-tumor production. From each patient, MOS retains unique patient tissue structure, genetic alterations, gene expression, immune microenvironment and histopathology. Overcoming major limitations of widely used, yet limited, models including ...
Manufactured by:Immune-Onc Therapeutics, Inc. based inPalo Alto, CALIFORNIA (USA)
Immune-Onc is evaluating IO-106, an antagonist antibody targeting LAIR1, an immune inhibitory receptor. The company’s preclinical research supports the proposed mechanisms of action of IO-106 and its evaluation as a potential treatment for solid ...
Manufactured by:Immune-Onc Therapeutics, Inc. based inPalo Alto, CALIFORNIA (USA)
Immune-Onc is evaluating IO-108, an antagonist antibody targeting the myeloid checkpoint, LILRB2 (also known as ILT4). The U.S. FDA has cleared the IND application for IO-108 as a potential therapy for solid tumors. The company expects to begin clinical trials with IO-108 in the second half of ...
Manufactured by:Xcell Biosciences Inc. based inSan Francisco, CALIFORNIA (USA)
The AVATAR System lets you fine-tune oxygen and pressure levels to cater culture conditions to your cell type of interest. Customizing settings based on tumor type or native microenvironment allows cells to behave as they would in vivo ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking to add functionality to your existing microscopy setup? The BioFlux 200 expands on BioFlux One by enabling up to 24 temperature-controlled flow cell assays in parallel. The dual flow control capability enables more complicated 2-phase flow assays. It is also compatible with the BioFlux Quattro for up to 96 parallel flow ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking for a simple microfluidic solution for your current microscope? The BioFlux One can run up to 24 simultaneous flow cell experiments and is ideal for platelet aggregation, leukocyte adhesion, and biofilm analysis. It works with your existing inverted microscope and is compatible with fluorescence, brightfield, phase and confocal ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking for a simple, fully integrated solution? The BioFlux DCIS integrates the BioFlux controller with a digital microscope, fluorescence, and two cameras. The easy-to-use live cell imaging system been designed with advanced capabilities to simplify demanding cell-based imaging applications with convenience and ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
Senti Bio has established, and continues to scale, a powerful Design-Build-Test-Learn development engine to generate our therapeutic gene circuits. Unique to Senti Bio’s approach is the speed, quantity and quality of the multiple types of gene circuits designed, resulting in thousands of gene circuits engineered to date. Senti Bio believes that this approach to programming gene circuits is ...
Manufactured by:Immune-Onc Therapeutics, Inc. based inPalo Alto, CALIFORNIA (USA)
Immune-Onc’s lead program is IO-202, an antagonist antibody targeting the myeloid checkpoint LILRB4 (also known as ILT3). Immune-Onc has a Phase I trial underway to evaluate IO-202 as a potential treatment for acute myeloid leukemia (AML) and chronic myelomonocytic leukemia ...
Manufactured by:Prellis Biologics, Inc. based inSan Francisco, CALIFORNIA (USA)
EXIS Human Immune Response: Prellis utilizes its proprietary holographic printing technology to engineer 3D printed lymph node organoids (LNOs) that recreates the human immunobiology in vitro allowing direct access to a fully functional human immune system. EXIS is a powerful and scalable platform with applications in antibody discovery (human and llama), immunogenicity evaluation, and in vitro ...
Manufactured by:Sigma-Aldrich based inBellefonte, PENNSYLVANIA (USA)
SynTumor is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically and morphologically realistic tumor ...