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Expressed Proteins Equipment Supplied In Usa Massachusetts
13 equipment items found
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our first ex vivo development candidate seeks to treat acute myeloid leukemia (AML) by engineering autologous T cell receptors (TCR) directed towards the Wilms’ Tumor 1 (WT1) antigen, an over-expressed protein that is often associated with AML and other cancers. We have nominated NTLA-5001 as our initial development candidate for AML and expect to enter the ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
Manufactured by:Ariana Pharma based inParis, FRANCE
Ariana Pharma has developed KEM® (Knowledge Extraction and Management) the most advanced Explainable Artificial Intelligence platform based on Galois Lattices (also known as Formal Concept Analysis or FCA). KEM® uses association rules to fully explore complex datasets in order to reveal hidden relationships and to derive new hypotheses. Ariana’s eXplainable Al reduces billions of ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
TP-1287 is an investigational oral CDK9 inhibitor that has shown favorable oral bioavailability in preclinical models. TP-1287 is enzymatically cleaved, yielding the active moiety, a potent inhibitor of CDK9.35 Inhibiting CDK9 is thought to downregulate the transcription of target genes, including MCL-1, reducing leukemic blast viability in MCL-1–dependent hematologic malignancies, and ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Pelabresib (CPI-0610) is an investigational selective small-molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. The compound has demonstrated a wide therapeutic window, with activity seen at a 48 mg ...
Manufactured by:Moderna, Inc. based inCambridge, MASSACHUSETTS (USA)
At Moderna, we are delivering on the promise of mRNA science to create a new generation of transformative medicines for ...
Manufactured by:BTX - Harvard Bioscience, Inc. based inHolliston, MASSACHUSETTS (USA)
It is also suitable for scale up to large volume electroporation for applications such as large-scale creation of engineered cells and large-scale protein ...
by:Aegle Therapeutics based inWoburn, MASSACHUSETTS (USA)
Aegle’s founder Dr. Evangelos Badiavas and his team have spent decades researching clinical applications of mesenchymal stem cells (“MSCs”) in severe dermatological disorders, including conducting clinical trials in burns and wounds under multiple INDs. In these trials, patients experienced accelerated healing, little to no scarring, total wound closure and tissue regeneration. ...
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
BRAF mutations are present in multiple types of cancer, including 40% in melanoma, 9% in colorectal cancer (CRC), and 2% in lung cancer. High levels of BRAF protein expression in these tumors suggest susceptibility to T cells targeting the mutation.3 Previous research has shown a durable complete response through transfer of tumor-infiltrating lymphocytes ...
Manufactured by:Rational Vaccines, Inc. based inWoburn, MASSACHUSETTS (USA)
One of the most celebrated achievements of modern medicine is the eradication of the smallpox virus with the use of a live-attenuated vaccine. We are advancing the applied science of attenuating live viruses to develop an entirely new class of therapeutic and prophylactic herpes treatments, vaccines and diagnostics, through rational design. Our technology is based on the pioneering research of ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
The Applied Biosystems QuantStudio 7 Pro Real-Time PCR System adds innovative smart features to the real-time PCR (qPCR) workflow, all in a compact footprint. With facial authentication, voice commands, Smart Help, multiplex capability, motorized interchangeable blocks, simplified workflow, intuitive software, automation capabilities, and large capacitive touch-screen interface, the QuantStudio 7 ...
Manufactured by:Ardigen based inKraków, POLAND
Bioinformatics Analysis & Drug Discovery in the era of Artificial Intelligence. The digital CRO team brings together scientists and engineers with diverse skill sets, ranging from biology and chemistry to statistics and machine learning. We work with both small startups and big pharmas to leverage digital power in order to enable the development of new therapies. We contribute to the entire ...
Manufactured by:BTX - Harvard Bioscience, Inc. based inHolliston, MASSACHUSETTS (USA)
Get a multifunctional electrofusion and square wave electroporation generator that meets your exact needs. Available product configurations by application, such as embryo manipulation or hybridoma production, make choosing the right system easy. For the ultimate in performance and convenience the ECM 2001+ offers advanced programming functions, preset protocols, and the most experimental ...