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In Vitro Equipment Supplied In Usa Massachusetts
38 equipment items found
Manufactured by:BMP Medical based inSterling, MASSACHUSETTS (USA)
BMP Medical has been producing components for In-Vitro Diagnostic (IVD) medical device testing for over 30 years. Many of the parts that we have developed with our customers have very intricate designs and features that set them apart from other products on the market. We work closely with our customers to provide support on the design and the ability to manufacture their ...
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
The Scissor N3 is an advanced in vitro model designed to simulate the subcutaneous injection of biopharmaceuticals. This device is particularly useful during the formulation development phase, enabling researchers to perform rank ordering of formulations and excipient screening. ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
APH-0912 is a combination of a Taxotere® prodrug and monoclonal antibody targeted to treat metastatic cancer. The prodrug is a combination of a docetaxel molecule, the potent anticancer drug, and a sugar molecule to enhance solubility covalently linked to a tumor-specific antibody. This molecular combination is not bioactive prior to administration. After infusion and adsorption onto targeted ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
Poor Solubility and Associated Formulation and Bioavailability Difficulties. Although paclitaxel is an effective anticancer drug, its solubility is low (~ 0.4 µg/mL), which limits its medical utility to intravenous applications. Docetaxel (Taxotere®) was developed as a paclitaxel derivative having improved water solubility; its solubility, however, is only ~ 14 µg/mL. Several ...
Manufactured by:NanoEnTek, Inc. based inGuro-gu, SOUTH KOREA
Quantitative immunoassay analyzing instrument that utilizes disposable cartridge to provide in vitro diagnostics ...
Manufactured by:Siemens Healthcare GmbH based inErlangen, GERMANY
The PFA-100® System measures the complex process of primary hemostasis and aids in the rapid detection of platelet dysfunction. It is the first commercially available in vitro testing system to incorporate high-shear flow in which the process of platelet adhesion and aggregation following a vascular injury is simulated ...
Manufactured by:CELLINK based inBoston, MASSACHUSETTS (USA)
PCL provides a reinforcing structure to load-bearing tissue constructs, including bone grafts and osteochondral plugs developed for in vitro and in vivo studies. It can also provide a temporary scaffold for overhanging ...
Manufactured by:Sekisui Diagnostics, LLC based inBurlington, MASSACHUSETTS (USA)
FastPack® IP Free PSA immunoassay is a chemiluminescent immunoassay for the in-vitro quantitative determination of free prostate-specific antigen (free PSA) in human serum. FastPack® IP Free PSA immunoassay is designed for use in conjunction with the FastPack® IP System for calculating the ratio of free/total PSA, expressed as a percentage (percent free ...
Manufactured by:BTX - Harvard Bioscience, Inc. based inHolliston, MASSACHUSETTS (USA)
The Gemini Twin Wave Electroporators are flexible systems allowing both square wave and exponential decay wave electroporation in a single unit. Ideal for all of your electroporation needs, including CRISPR, in vivo, in vitro, in ovo and more. Systems for cuvettes or plates. These waveform combinations enable researchers to easily and efficiently electroporate eukaryotic and ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. The quad-culture Emulate Liver-Chip combines four human cell types in a dynamic microenvironment to support in vivo like gene expression, functionality, and ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro has spent 20 years specializing in neuroscience imaging solutions for preclinical, early phase and late phase clinical studies. Our capabilities span from in vitro assays to in vivo imaging using PET, SPECT and MRI imaging biomarkers in CNS drug development and CNS clinical trials. We have expertise in coordinating worldwide multi-center imaging studies, and providing ...
Manufactured by:TargetMol Chemicals Inc. based inWellesley Hills, MASSACHUSETTS (USA)
GLPG3312 is a selective and potent pan-SIK inhibitor with the advantage of oral activity, with IC50=0.6-2.0 nM for SIK1, SIK2 and SIK3, and exhibits anti-inflammatory and immunomodulatory activity in both human primary myeloid cells and mouse ...
Manufactured by:Genovis Group based inKävlinge, SWEDEN
GlyCLICK is a site-specific conjugation technology for IgG using Fc glycan remodeling and click-chemistry. The technology generates stable and homogenous antibody conjugates for IgG from several species and subclasses. Fc-glycan remodeling by complete deglycosylation of the antibody allows for site-specific conjugation using robust click-chemistry, resulting in a degree of label (DOL) or ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
TP-0184 is an investigational inhibitor of activin receptor-like kinase 2 (ALK2) and ALK5 (also known as TGFβR1). This bimodal inhibitor is believed to downregulate multiple TGF-β superfamily signaling pathways and has shown antitumor activity in several ...
Manufactured by:NanoEnTek, Inc. based inGuro-gu, SOUTH KOREA
BUDDI™ is an image analyzer that evaluates the line signal intensities on the test ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Adenoviral vectors offer high levels of transgene expression in broad cell types, including dividing and non-dividing cells. Adenoviral vectors are the method of choice whenever fast and transient gene expression for a very large gene or several genes is required, since the expression cassette has a total capacity of 7.5 kb. This provides space for flexible vector design with multiple transgenes ...
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Automated sorting and isolation of single spheroids and organoids. A game-changer in drug screening and other applications where standard 3D models will gradually replace traditional animal models. spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling. Using precision dispensing technology together with advanced image-based sorting ...
by:OSSIO Inc based inWoburn, MASSACHUSETTS (USA)
OSSIOfiber® Cannulated and Solid-Core Fixation Nails allow surgeons to offer patients a strong and biointegrative solution for a wide range of surgical techniques. Comprised of OSSIOfiber® Intelligent Bone Regeneration Technology, Fully integrates into native anatomy without adverse inflammation,, as proven in pre-clinical studies, Rivals performance of metal headless cannulated ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
DSP-0390 is an emopamil-binding protein (EBP) inhibitor. EBP is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis.47 When functional, EBP mediates de novo cholesterol synthesis for cell membrane structure and signaling, enabling aberrant growth of tumors.47-50 Inhibition of EBP causes an accumulation of its substrates zymostenol and zymosterol, which contributes to ...