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Leukemia Aml Equipment Supplied In Usa Massachusetts

4 equipment items found
In MassachusettsAvailable In MassachusettsNear Massachusetts

Intellia - Ex Vivo Therapies

Intellia - Ex Vivo Therapies

by:Intellia Therapeutics, Inc.   based inCambridge, MASSACHUSETTS (USA)
We plan to initiate patient screening for a first-in-human Phase 1 study of NTLA-5001, a WT1-directed TCR T cell therapy for the treatment of AML, by the end of 2021. Our first ex vivo development candidate seeks to treat acute myeloid leukemia (AML) by engineering autologous T cell receptors (TCR) directed towards the Wilms’ Tumor 1 (WT1) ...
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Sumitomo - Model DSP-5336 - Menin-MLL Binding Inhibitor

Sumitomo - Model DSP-5336 - Menin-MLL Binding Inhibitor

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
DSP-5336 is a small molecule inhibitor against the binding of menin and mixed-lineage leukemia (MLL) protein. Menin is a scaffold nuclear protein that plays various key roles in biological pathways, including cell growth regulation, cell cycle control, genomic stability, bone development, and hematopoiesis.26,27 Binding of menin to MLL fusion and wildtype proteins leads to the upregulation of ...
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VOR - Model VOR33 (CD33) - Hematopoietic Cells

VOR - Model VOR33 (CD33) - Hematopoietic Cells

by:Vor Biopharma   based inCambridge, MASSACHUSETTS (USA)
VOR33 is our lead eHSC product candidate designed to replace the standard of care in transplant settings. Once the VOR33 cells have engrafted, we believe that patients can be treated with anti-CD33 therapies, such as Mylotarg or VCAR33, with limited on-target toxicity, leading to durable anti-tumor activity and potential cures. In preclinical studies, we have observed that the removal of CD33 ...
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Model ClearSeq AML - NGS Disease Research Panels

Model ClearSeq AML - NGS Disease Research Panels

Manufactured by:Agilent Technologies, Inc.   based inSanta Clara, CALIFORNIA (USA)
The ClearSeq AML panel targets 20 genes identified by leading researchers to be frequently mutated in acute myeloid leukemia (AML). It is designed for full coverage of target regions with multiple amplicons covering each target for greater confidence in somatic variant calling. ...
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