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Alzheimer Equipment Supplied In Usa
147 equipment items found
Manufactured by:C2N Diagnostics based inSt. Louis, MISSOURI (USA)
The test aims to help physicians better determine the presence or absence of amyloid plaques in the brain, a hallmark sign of Alzheimer’s ...
Manufactured by:Vitruvian BioMedical, Inc. based inAddison, TEXAS (USA)
VITRUVIAN has obtained the Exclusive Global License for a Therapeutic Vaccine for the Prevention of Alzheimer's Disease. YM7555 - Alzheimer’s Disease Therapeutic Vaccine targeting ABeta and TAU. VITRUVIAN has received an Exclusive Global License for YM7555 which is a Therapeutic Vaccine technology for the prevention of Alzheimer’s ...
by:Vaxxinit based inDallas, TEXAS (USA)
Targets toxic forms of aggregated Aβ in the brain to fight Alzheimer’s. Phase 1, Phase 2a and Phase 2a LTE trials have shown UB-311 to be well tolerated in early AD subjects over three years of repeat dosing, with a safety profile comparable to placebo, with no cases of amyloid-related imaging abnormalities-edema (“ARIA-E”) in the main study. ...
Manufactured by:Vivid Microscopy, LLC based inWauwatosa, WISCONSIN (USA)
Cell sorting is a very important aspect in numerous diseases. Results show SEMKUR-cell sorting probe being used to differentiate Alzheimer's cells that have been treated with a prospective drug. ...
by:Oligomerix, Inc. based inWhite Plains, NEW YORK (USA)
There exist numerous rare diseases that tau dysfunction is associated with known as tauopathies. While Alzheimer’s is the largest tauopathy, other tauopathies are rare diseases that present accelerated regulatory pathways and significant near-term commercial opportunities. These rare diseases shown in Chart A below have a tau etiology similar to AD. Oligomerix’s 1st ...
Manufactured by:MagQu LLC USA based inSurprise, ARIZONA (USA)
Amyloid β (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is being cut by certain enzymes to yield Aβ. One of the most common ...
Manufactured by:C2N Diagnostics based inSt. Louis, MISSOURI (USA)
The PrecivityAD® test measures the concentrations of amyloid beta 42 and 40 (Aβ42 and Aβ40), as well as the presence of Apolipoprotein E (ApoE) isoforms in the blood. The test indicates if an individual is likely to have amyloid plaques in the brain, a hallmark of Alzheimer’s disease. ApoE4 genotype is a significant risk factor for brain amyloid accumulation ...
Manufactured by:Woolsey Pharmaceuticals, Inc. based inNew York City, NEW YORK (USA)
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are rare neurodegenerative disorders associated with the accumulation of insoluble deposits of predominantly 4 microtubule binding domain repeat (4R) tau protein in specific brain regions, mainly in the absence of other pathogenic proteins including β-amyloid, which is found in Alzheimer’s ...
Manufactured by:Leucadia Therapeutics based inRiverside, CALIFORNIA (USA)
Cerebrospinal fluid (CSF) clears toxic metabolites from intercellular spaces in the brain, much as the lymphatic system does in the rest of the body. The first regions of the brain to be impacted by Alzheimer's disease are cleared by CSF that drains across a porous bone called the cribriform plate. Aging and life events can occlude the cribriform plate and reduce the ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
mGlu2 NAM for the treatment of mild neurocognitive disorders, or mNCD. We are developing mGlu2 NAM as a novel orally available treatment for mNCD associated with Alzheimer’s disease, Parkinson’s disease and depressive disorders. The program is in clinical candidate selection phase and we expect to enter IND enabling studies early in H2 ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Neuroscience is a heterogeneous field, requiring integrated analysis of multiple cell types, tissues and organs using diverse techniques. Prevention and effective treatment of neurological disorders like Alzheimer's and Parkinson's diseases has been a major medical challenge. ...
Manufactured by:BioXcel Therapeutics, Inc. based inNew Haven, CONNECTICUT (USA)
It is being investigated for at-home use for the acute treatment of agitation in bipolar and schizophrenia patients, for agitation in Alzheimer’s disease, and as an adjunctive treatment for major depressive ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
Reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Orally active and brain penetrant.http://www.creative-peptides.com/product/pmx-item-10-101-154-33641.html ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Alkahest, with its partner Grifols, is developing lead clinical candidates, GRF6019 and GRF6021, as potential treatments for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease with cognitive impairment. Designed to safely replenish regenerative positive chronokines that decrease with age, GRF6019 and GRF6021 are highly selected human ...
Manufactured by:MagQu LLC USA based inSurprise, ARIZONA (USA)
When tau proteins become defective, It will result in the self-assembly of tangles in brain and increased some neurodegenerative diseasesincluding Alzheimer’s disease (AD)?Pick's disease?Parkinson's disease (PD)?Progressive supranuclear palsy(PSP) and Corticobasal degeneration ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length ...
Manufactured by:SOFIE based inDulles, VIRGINIA (USA)
Neuraceq is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer’s Disease (AD) and other causes of cognitive decline. ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
An alpha (α)-secretase modulator for ameliorating Alzheimer’s Disease pathophysiology and cognitive impairment with neuroprotection. Aphios is developing APH-1104, a more potent analog of Bryostatin-1, which is neuroprotective by α-secretase activation via novel PKC isoforms, down-regulation of pro-inflammatory and angiogenic processes and the substitution of ...
Manufactured by:Cirtec Medical based inBrooklyn Park, MINNESOTA (USA)
Signaling a Better Life: Neuromodulation devices are changing the game for treatment of spinal pain, hearing and vision loss, as well as stroke rehabilitation and tremor management. Further research is targeting treatment of Alzheimer’s disease, sleep disorders, arthritis and other chronic ...
Manufactured by:C2N Diagnostics based inSt. Louis, MISSOURI (USA)
The PrecivityAD® test identifies whether a patient is likely to have the presence or absence of amyloid plaques in the brain, a pathological hallmark of Alzheimer’s disease. The test relies on precise and robust quantitation of Amyloid Beta 42/40 ratio (Aβ 42/40) and detection of Apolipoprotein E proteotype (equivalent to ApoE genotype) in blood samples, using ...
