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Gene Therapy Equipment Supplied In Usa
84 equipment items found
Manufactured by:Novartis International AG based inBasel, SWITZERLAND
Our investigational gene therapy, GT005, is designed to restore balance to a part of our immune system called the complement ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
ImmTOR has significant potential to mitigate unwanted immune responses and induce AAV-specific tolerance to enable redosing of gene therapies. ImmTOR has the potential to administer multiple low doses to achieve therapeutic benefit without risk of overdosing, the ability to treat patients typically excluded from these treatments and is a novel approach to ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Engineered with membrane-bound IL15, Eliminates toxic IL2 regimen, increasing patient accessibility to TIL therapy, Drives improved persistence, IL15 expression controlled by acetazolamide (ACZ), via cytoDRiVE® ...
Manufactured by:Clearside Biomedical based inAlpharetta, GEORGIA (US) (USA)
We believe our platform offers the potential for safer, targeted ocular gene therapy without some of the risks of surgery and subretinal administration. Suprachoroidal administration of gene therapy could ultimately enhance access to care because it does not require specialized gene therapy ...
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
OCU410 (AAV-RORA) is a modifier gene therapy product candidate being developed for the treatment of dry age-related macular degeneration (Dry AMD). OCU410 utilizes an AAV delivery platform for the retinal delivery of the RORA (RAR Related Orphan Receptor A) gene. Various genes associated with AMD are regulated by RORA. ...
Manufactured by:Unchained Labs based inPleasanton, CALIFORNIA (USA)
Stunner is the only system that pulls together UV/Vis concentration, Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) data from the same 2 μL sample. Dig in to your AAV to get the total capsid titer and empty/full ratio, or rack up payload concentration and size data on any nanoparticle all at once. Nail down your protein quality by knocking concentration, hydrodynamic size, ...
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
OCU400 (AAV-NR2E3) is a novel gene therapy product candidate with the potential to be broadly effective in restoring retinal integrity and function across a range of genetically diverse inherited retinal diseases (“IRDs”). It consists of a functional copy of a nuclear hormone receptor (“NHR”) gene, NR2E3, delivered to ...
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
Ocugen’s modifier gene therapy platform is a cutting-edge technology licensed from the Schepens Eye Research Institute of Massachusetts Eye and Ear (Harvard Medical School) and involves targeted delivery and expression of one or more nuclear hormone receptor genes (NHRs) in the disease tissues. ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
Selecta’s wholly owned gene therapy program for the treatment of ornithine transcarbamylase (OTC) deficiency is expected to enter the clinic in 2022. OTC deficiency is a genetic disorder urea cycle that causes ammonia to accumulate in the blood. The most severe form of the disorder presents within the first few days of life. ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
Selecta’s first ImmTORTM + gene therapy candidate MMA-101 for methylmalonic acidemia (MMA) is expected to enter clinical trials the end of 2021. MMA is a rare metabolic disease that may lead to metabolic acidosis and hyperammonemia and is associated with long-term complications including feeding problems, developmental delay, intellectual disability, and ...
Manufactured by:XyloCor Therapeutics based inWayne, PENNSYLVANIA (USA)
XC001 is an investigational gene therapy for the treatment of patients with refractory angina with no treatment options. Patients who have exhausted pharmacologic options and are not eligible for PCI or coronary artery bypass grafts become sedentary because of their symptoms and this can exacerbate comorbidities causing rapid deterioration of their health status ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genetic diseases are caused by defective genes. Gene replacement therapy aims to treat such diseases by introducing a corrective gene into a patient’s body; the corrective gene can be a normal copy of the defective gene, or a copy that is engineered to provide enhanced biological activity; ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genome editing technologies enables permanent modifications to the genome by harnessing the activities of certain enzymes (e.g. nucleases and integrase) and invoking DNA repair mechanisms at specific locations in the genome. As a therapeutic modality, genome editing can correct a defective gene, disrupt a deleterious gene, or target a therapeutic gene to a precise location in the genome for safe ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
Gene therapy holds the promise of treating the unmet needs of patients who suffer from a rare genetic disease. An estimated 4,000 medical conditions are a result of gene disorders with no previous targeted treatments. Gene therapy offers new options away from the conventional symptomatic approach to disease ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
Plasmid DNA is a critical raw material for advanced therapeutics including mRNA- and viral vector-based cell and gene therapies and vaccines. To support your therapeutic programs, the Catalent team has broad expertise in developing customized plasmid DNA manufacturing solutions, from plasmid R&D services to large-scale CGMP plasmid production. ...
Manufactured by:Charter Medical, LLC based inWinston-Salem, NORTH CAROLINA (USA)
Charter Medical’s Advect® Fluid Transfer Sets are designed to support the quality and manufacturing requirements of personalized care. The transfer sets are intended for sterile transfer of bone marrow mononuclear cells from one container to another. ...
Manufactured by:Krishgen Biosystems based inMumbai, INDIA
Adeno-Associated Virus (AAV) is a nonpathogenic virus that is widely used as vector in gene therapy. KRISHGEN currently provides full range of adeno-associated virus (AAV) assay kits that specifically recognize intact virus capsids as well as antibodies specific to AA-viral subunits and replicases. Titration ELISA kits for various AAV subtypes are also ...
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Manufactured by:AB Sciex LLC based inFramingham, MASSACHUSETTS (USA)
Perform consistent and compliant biotherapeutics characterization faster than ever. With the PA 800 Plus system, you can confidently safeguard the success of your biologics. Run multiple characterizations from a single system that biopharma labs depend on, and produce qualitative and quantitative analyses, with speed and ...
Manufactured by:Alfa Wassermann Separation Technologies (AWST) based inWest Caldwell, NEW JERSEY (USA)
The KII system is designed to expertly perform in FDA approved processes for the manufacture of viral vaccines, particulate proteins, gene therapies and ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Manufacturers of adeno-associated viral (AAV) vectors need to scale up quickly and cost-effectively to meet the increasing demand from the gene therapy market. But testing and optimizing multiple catalog media takes time and expertise. What if you had a panel of media and an expert in media optimization to help ...