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Targeted Molecular Equipment Supplied In Usa
26 equipment items found
Manufactured by:CMR Naviscan Corporation based inCarlsbad, CALIFORNIA (USA)
The Stereo Navigator™ enables physicians to target and guide biopsy devices toward abnormalities visible on Breast PET, facilitated by the biopsy software that displays needle target position and suggested trajectory to obtain tissue samples for pathologic evaluation. The cutting edge in targeted molecular imaging of ...
Manufactured by:MuseChem based inPaoli, PENNSYLVANIA (USA)
Hydrocortisone(CAT: A000475), also known as cortisol, is extracted from the adrenal cortex and is the adrenocortical hormone with the strongest effect on carbohydrate metabolism, which is a kind of glucocorticoid. This product is mainly used in medical research and development and other scientific research ...
Manufactured by:Elabscience based inHouston, TEXAS (USA)
Western Blot (WB) is one of the most conventional biological experiments. SDS-PAGE gel is used to transfer the separated proteins to the membrane (such as PVDF membrane). Then, the target protein is detected by the specific antibody that recognizes the target protein, and the specific antibody is recognized by the labeled second antibody. The technique is widely used to detect the expression of ...
by:T2 Biosystems, Inc. based inLexington, MASSACHUSETTS (USA)
T2MR® technology powers all of the diagnostic innovations at T2 Biosystems. T2MR is a diagnostic detection method utilizing miniaturized magnetic resonance technology which measures how water molecules react in the presence of magnetic fields. Over 200 studies published in peer-reviewed journals have featured T2MR in a breadth of applications, including direct detection and measurement in ...
by:AptaMatrix, Inc. based inSyracuse, NEW YORK (USA)
Aptamers are DNA/RNA molecules that have affinities for their targets similar to antibodies. Aptamers have shown great potential to replace antibodies in biosensors, point-of-care diagnostics, therapeutics, and all of the areas currently dominated by antibodies. Once aptamers have been identified, they can be produced for less than 10% of the cost of antibodies. The commercial value of antibodies ...
Manufactured by:Accelerate Diagnostics, Inc. based inTucson, ARIZONA (USA)
MALDI prep. Simplified. Automated rapid clean-up of blood cultures for direct ID by ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
Allosteric modulators are an emerging class of orally available small molecule therapeutic agents that may offer a competitive advantage over classical ...
Manufactured by:Axial Therapeutics Inc. based inWoburn, MASSACHUSETTS (USA)
Addressing Unmet Medical Needs in Autism Spectrum Disorder. According to the Centers for Disease Control and Prevention (CDC), approximately 1 in 54 children has been identified with Autism Spectrum Disorder (ASD). Core symptoms of ASD include impairments in social interaction, communication, and the presence of stereotyped repetitive behaviors. Co-occurring conditions that impact quality of life ...
Manufactured by:Kura Oncology, Inc. based inSan Diego, CALIFORNIA (USA)
With the advent of precision medicines that can target unique molecular or genetic features of a patient’s tumor, the field of oncology has a host of alternatives to one-size-fits-all treatments. This is a major advance over traditional chemotherapy, which can be as potent against healthy tissue as it is against cancer. Using tumor genomic profiling and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM)[1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of ...
Manufactured by:RayBiotech Life, Inc. based inPeachtree Corners, GEORGIA (US) (USA)
Combining direct antigen-labeling technology with our vast library of array-validated antibodies, RayBiotech has created our largest antibody array to date: the Human L6000 Array. With the L-Series high density array platform, researchers can now detect up to 6000 proteins simultaneously, obtaining a broad, panoramic view of protein expression. Our newly expanded panel includes a wide variety of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
IMS2186 is an anti-choroidal neovascularization (CNV) agent that inhibits angiogenesis upstream of VEGF. IMS2186 can arrest cancer cell cycle in G2/M phase, thus exerting anti-proliferation and anti-angiogenesis effects. IMS2186 has no intraocular toxicity and reduces the amount of eye leakage and diseased ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC). Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, ...
Manufactured by:RayBiotech Life, Inc. based inPeachtree Corners, GEORGIA (US) (USA)
Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays. The RayBio® Membrane-Based Antibody Arrays (C-Series) are tools for screening and comparing expression levels of many cytokines, growth factors, proteases, soluble receptors, and other proteins in a wide variety of sample types. The C-Series Arrays utilize the sandwich immunoassay principle, wherein a panel of capture antibodies is ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection ...