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Targeted Protein Equipment Supplied In Usa
71 equipment items found
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Manufactured by:Bertin Technologies based inMontigny-le-Bretonneux, FRANCE
Myelotracker® is an innovative fluorescent tool designed to easily identify neutrophils, key cells of the immune system, in blood and tissues. It provides researchers with a reliable solution for studying inflammation, infections, and immune responses. ...
Manufactured by:Elabscience based inHouston, TEXAS (USA)
Western Blot (WB) is one of the most conventional biological experiments. SDS-PAGE gel is used to transfer the separated proteins to the membrane (such as PVDF membrane). Then, the target protein is detected by the specific antibody that recognizes the target protein, and the specific antibody is recognized by ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
Agonist refers to substances that activate a specific target protein. It can easily be viewed as the opposite of inhibitor. Until now, Deargen's drug-target interaction (DTI) was predicted based on the binding affinity between the substance and the target protein, which causes barrier to distinguish between the ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
PROTAC-Proteolysis targeting chimera is a technology that induces the Ubiquitin-Proteasome System (UPS) to degrade the target protein. When the target protein (Protein of Interest (POI)) is ubiquitinated by the ligase of E1, E2, E3, the proteasome recognizes that part of the ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
To hinder or inhibit the function of proteins that cause disease, many pharmaceutical companies develop drugs called inhibitors. Each of the 20,000 proteins in the human body has its own unique functions. Depending on the function of the protein, it can be classified into enzyme proteins, ion channel proteins, ...
by:LifeSensors Inc based inMalvern, DELAWARE (USA)
Ubiquitin is a small polypeptide that is conjugated via its C-terminus to an ε-amino group of lysine on a target protein; this conjugation is referred to as monoubiquitylation. Subsequently, additional ubiquitin moieties can be conjugated to the initial ubiquitin, utilizing any of seven lysine residues (K6, K11, K27, K29, K33, K48, K63) on the surface of ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
ADC (Antibody-drug conjugate) is a next-generation antibody-drug conjugate that has improved efficacy over existing antibodies. This drug combines the advantages of two factors: target specificity, which is a characteristic of an antibody, and cytotoxicity, which is a characteristic of a drug. Specifically, this is a technology focused on targeting and killing ...
Manufactured by:LifeTein, LLC based inHillsborough, NEW JERSEY (USA)
LifeTein’s unique coupling chemistry enables fast and efficient conjugation of amino (-NH2) or thiol (-SH) containing proteins and peptides, to the solid core with iron oxide clusters. All steps in the coupling are performed at physiological conditions and at room temperature with high yields and short reaction times. The Amine-Terminated Magnetic Beads are silica-based ...
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
CISH (Cytokine Inducible SH2 Containing Protein) contains a SH2 domain and a SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CISH may be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
NX-5948 (BTK-IN-24) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. ...
Manufactured by:Rockland Immunochemicals, Inc. based inLimerick, PENNSYLVANIA (USA)
Rabbit IgG TrueBlot® is a unique horseradish peroxidase conjugated Anti-Rabbit IgG monoclonal secondary antibody. Rabbit IgG TrueBlot® enables detection of immunoblotted target protein bands, without hindrance by interfering immunoprecipitating immunoglobulin heavy and light chains. It is easy to generate publication-quality IP/Western Blot data with ...
by:NanoPin Technologies Inc. based inNew Orleans, LOUISIANA (USA)
This approach has several advantages, since serum digestion cleaves all factors that may interact with a biomarker target to remove their masking effect and increase the amount of target protein available for analysis, while pathogen-derived peptides biomarker peptides produced during this digestion can be used to uniquely distinguish highly ...
by:Vir Biotechnology, Inc. based inSan Francisco, CALIFORNIA (USA)
Moving beyond more traditional approaches that are used to evoke adaptive immunity or that directly target pathogens, where the development of resistance can occur, we plan to target host proteins as a means of creating host-directed therapies with high barriers to resistance. We believe that by leveraging the power of innate immunity, we can ...
by:Vaxxinit based inDallas, TEXAS (USA)
We are developing an anti-tau product candidate that has the potential to address multiple neurodegenerative conditions, including AD, by targeting abnormal tau proteins alone and in potential combination with other pathological proteins such as Aβ to combat multiple pathological processes at ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Revvity’s gene delivery team, where SIRION Biotech’s expertise lives on, has been partnering with pharma and biotech organizations for many years to provide improved viral vectors using our AAV ...
Manufactured by:Aurinia Pharmaceuticals Inc. based inVictoria, BRITISH COLUMBIA (CANADA)
AUR200 is a recombinant Fc fusion protein designed to specifically block B-cell Activating Factor, known as BAFF, and A Proliferation-Inducing Ligand, known as APRIL. BAFF and APRIL promote B cell survival and differentiation and have been shown to play a prominent role in the pathogenesis of certain autoimmune and nephrology conditions. AUR200 is currently undergoing pre-clinical development ...
Manufactured by:CD BioSciences based inShirley, NEW YORK (USA)
Full length Clone DNA of Rhesus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide with C terminal His ...
by:BellBrook Labs based inMadison, WISCONSIN (USA)
AptaFluor SAH Methyltransferase Assay directly measures SAH produced by methyltransferase enzymes during methylation. These enzymes methylate a variety of substrates using S-adenosylmethionine (SAM) as the methyl donor, leaving the common product S-adenosylhomocysteine (SAH). These SAH measurements allow researchers to effectively determine the activity of the methyltransferase enzyme. The ...
Manufactured by:CD BioSciences based inShirley, NEW YORK (USA)
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ, and η that have been identified in ...
Manufactured by:CD BioSciences based inShirley, NEW YORK (USA)
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ, and η that have been identified in ...