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Aptamer Equipment & Supplies Near Micronesia
15 equipment items found
Manufactured by:LifeTein, LLC based inHillsborough, NEW JERSEY (USA)
LifeTein’s unique coupling chemistry enables fast and efficient conjugation of amino (-NH2) or thiol (-SH) containing proteins and peptides, to the solid core with iron oxide clusters. All steps in the coupling are performed at physiological conditions and at room temperature with high yields and short reaction times. The Amine-Terminated Magnetic Beads are silica-based superparamagnetic ...
by:Base Pair Biotechnologies, Inc. based inPearland, TEXAS (USA)
The determination of aptamer-target binding characteristics is an important tool in the aptamer discovery process. Affinity determination with Bio-Layer Interferometry (BLI) can be used to select aptamer candidates for specific downstream applications, identify matched aptamer pairs, and optimize buffer formulations. BLI is routinely used for characterization of aptamer candidates and ...
by:BellBrook Labs based inMadison, WISCONSIN (USA)
AptaFluor SAH Methyltransferase Assay directly measures SAH produced by methyltransferase enzymes during methylation. These enzymes methylate a variety of substrates using S-adenosylmethionine (SAM) as the methyl donor, leaving the common product S-adenosylhomocysteine (SAH). These SAH measurements allow researchers to effectively determine the activity of the methyltransferase enzyme. The ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Utilizing our proprietary Sword Swift™ Method Development Process and Sword Swift™ Detection Reagents, our scientists can develop sensitive quantitative assays to measure the amounts of free or bound drug in preclinical or clinical samples with high accuracy and ...
by:Alfa Cytology based inU.S. VIRGIN ISLANDS
P12FR2 aptamer sodium is a 2'-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. The P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in a wound healing assay and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer ...
by:AptaMatrix, Inc. based inSyracuse, NEW YORK (USA)
Aptamers are DNA/RNA molecules that have affinities for their targets similar to antibodies. Aptamers have shown great potential to replace antibodies in biosensors, point-of-care diagnostics, therapeutics, and all of the areas currently dominated by antibodies. Once aptamers have been identified, they can be produced for less than 10% of the cost of antibodies. The commercial value of antibodies ...
by:CIS Pharma AG based inBubendorf, SWITZERLAND
CIS Pharma develops novel antibody-drug- conjugates (ADCs) based on our proprietary polymer carrier platform. Our polymers serve as carriers that are loaded with cytotoxic drugs, radioisotopes or other active entities. The carrier together with its cargo is conjugated to a target-specific antibody using site-directed linker chemistry, different from the linker chemistry used to attach the ...
by:Taiwan Liposome Company, Ltd. (TLC) based inNangang Distric, TAIWAN
TLC is committed to creating solutions for longstanding challenges in drug development by enabling new therapies with entirely unique properties. TLC has proprietary solution for pharmaceutical product development called LipAD®. LipAD® allows the design of medicines at the nanometer scale, improving drug solubility, protecting molecules from degradation, or targeting drug delivery to ...
Manufactured by:RayBiotech Life, Inc. based inPeachtree Corners, GEORGIA (US) (USA)
The Cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4) Epitope Mapping Peptide Array is a semi-quantitative array displaying 177 synthesized peptides representing the full-length CTLA4. It is suitable for antibody epitope mapping and detection of IgG, IgA, IgM, IgE, etc. in serum, plasma, and many other liquid sample types. ...
Manufactured by:Qualigen Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
QN-247, formerly referred to as ALAN (Aptamer Linked Anti Nucleolin), is an aptamer-based investigational drug candidate currently under development and evaluation with the potential to treat a variety of different cancer types, including liquid and solid tumors. A key component of this drug candidate, the QN-165 aptamer, has been tested in over 100 cancer patients and is well tolerated with no ...
by:Pure Biologics SA based inWroclaw, POLAND
Myasthenia gravis (MG) is an autoimmune condition classified as a rare disease. Accordingly, myasthenic patients lack effective treatment options, as this rare disease is not a primary interest of the pharmaceutical industry. However, considerable social and institutional support exists for the development of new therapies to treat rare diseases. The PB005 (AptaMG) project aims to develop a novel ...
Manufactured by:Manzanita Pharmaceuticals, Inc. based inWoodside, CALIFORNIA (USA)
Nervelight™, a topical, intraoperative nerve imaging agent that is selective for at-risk nerve tissue in cancer ...
by:Pure Biologics SA based inWroclaw, POLAND
Neuromyelitis optica (NMO) is an neurological autoimmune condition classified as a rare disease. Because of this classification, NMO lacks effective treatment options, since it is not of primary interest to the pharmaceutical industry. However, considerable social and institutional support exists for developing new therapies for such rare diseases. The PB002 (AptaPheresis) project aims to ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell ...