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Alfa Chemistry Active Pharmaceutical Ingredients Services Available In Canada
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Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
MRTX0902 is a potent SOS1 inhibitor which can be used for the therapeutic intervention of KRAS-driven (Kirsten rat sarcoma virus driven) cancers. Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with KRAS being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in human cancers and is present in 35% of lung adenocarcinomas ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Acetazolamide is a white to yellowish-white fine crystalline powder that is slightly soluble in acetone, insoluble in chloroform, diethyl ether and carbon tetrachloride. The chemical name of it is 2-acetamido-1,3,4-thiadiazole-5-sulfonamide. Acetazolamide is a first-generation carbonic anhydrase (CA) inhibitor, which is most commonly used in the treatment of glaucoma. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Sulfamethoxazole, a sulfanilamide, is a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase and inhibits the conversion of PABA to dihydrofolic acid. Inhibition of this pathway ultimately prevents the synthesis of folate that is a critical role during DNA synthesis. Therefor, sulfamethoxazole can inhibit the growth and replication of ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Chlorquinaldol is monohydroxyquinoline, or quinolin-8-ol that is substituted by a methyl group at position 2 and chlorine at positions 5 and 7. It is a solid insoluble in water and the chemical name of chlorquinaldol is 5,7-dichloro-2-methyl-8-hydroxyquinoline. Chlorquinaldol is an antimicrobial agent used in the treatment of bacterial vaginosis. Alfa Chemistry offers high quality chlorquinaldol. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cyclophosphamide: Cyclophosphamide, also known as cytophosphane, appears as a white to almost white crystalline powder with a slightly bitter taste. The chemical name of it is p-[N,N-bis-(2-chloroethyl)]-1-oxo-3-nitrogen-2-phosphocyclohexane-p-oxide monohydrate. Cyclophosphamide is a synthetic alkylating agent chemically related to nitrogen mustard with antineoplastic and immunosuppressive ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Methotrexate, one of the earliest cancer chemotherapy agents, which is extensively used in the treatment of cancer, including breast cancer, leukemia, lung cancer, lymphoma, osteosarcoma and so on. The efficacy of methotrexate mainly due to its inhibitory effect on dihydrofolate reductase (DHFR)[1]. DHFR catalyzes the conversion of dihydrofolate to the active tetrahydrofolate that is needed for ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Benzhexol hydrochloride is a class of antimuscarinic drug with the chemical name (±)-a-cyclohexyl-1-phenyl-3-(1-piperidinyl)-propanol hydrochloride. It was approved by the FDA for the treatment of Parkinson's disease (PD) in the United States in 2003. By improving muscle stiffness, benzhexol hydrochloride allows the body to move normally. Alfa Chemistry offers high quality benzhexol ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cytarabine Hydrochloride: Cytarabine hydrochloride is a white to off-white crystalline with the chemical name 1-β-D-arabinofuranosyl-4-amino-2(1H)-pyrimidinone hydrochloride. Cytarabine hydrochloride is used in chemotherapy for white blood cell cancers, especially acute myeloid leukemia (AML). ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Ancitabine Hydrochloride: Ancitabine hydrochloride is a white needle-like crystal or crystalline powder that is freely soluble in water, slightly soluble in methanol and ethanol, and almost insoluble in ether, benzene and chloroform. The chemical name of it is 2-methanolyl 2,3,3a,9a-tetrahydro-3hydroxy-6-imino-6H furan-(2',3',4,5)-oxazole(3,2a) pyrimidine hydrochloride. Ancitabine hydrochloride ...