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Human Cancer Services
9 services found
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
MRTX0902 is a potent SOS1 inhibitor which can be used for the therapeutic intervention of KRAS-driven (Kirsten rat sarcoma virus driven) cancers. Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with KRAS being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Nude rat xenograft models provide a more appropriate platform that conquers the limitations of traditional in vivo models and more precisely represent human cancer features especially in relation to metastasis and drug ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing its payload efficacy. However, prior to in vivo deployment, information regarding basic biochemical characteristics and in vitro efficacy must be acquired for a proper ...
Manufactured by:Advanced Cell Diagnostics, Inc. based inNewark, CALIFORNIA (USA)
ACD has curated a collection of dozens of pre-sourced validated and un-validated tissue blocks, available to our PAS customers, to support the development of ISH probes and assays. ...
Manufactured by:BioMark Diagnostics Inc. based inRichmond, BRITISH COLUMBIA (CANADA)
Liquid Biopsy Metabolic Panels Being Developed for Other Cancers; Glioblastoma (GBM), Breast Cancer, Head & Neck ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Pharmaceutical chemical and biology researchers need to develop new methods and models to improve the predictivity of preclinical discovery phases and increase the number of good molecules in clinic. INOVOTION’s unique in vivo technology will allow you to raise the global number of drug candidates tested in clinic without increasing your ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
One of the main obstacles in drug development is how to deliver drugs effectively to target cells. In general, macromolecules such as proteins and mRNA cannot penetrate the cell membrane because the cell membrane has acquired protective mechanisms through evolution. However, viruses can deliver their genetic material into cells. Therefore, viruses and virus-like particles are widely used to ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...