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Cytotoxic Services In Europe
18 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Antibody-drug conjugates employ the specific monoclonal antibodies (mAbs) to achieve targeted delivery of the conjugated cytotoxic molecules to tumor cells. This delicate design increases the payload efficacy against tumor cells and in the meantime, reduces the cytotoxicity of the otherwise highly toxic payload to normal tissues comparing to traditional ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload). A payload drug can be attached to different sites on an antibody using diverse conjugation chemistry. Multiple endogenous amino acids can serve as potential conjugation sites. However, to achieve more precisely ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload). A payload drug can be attached to different sites on an antibody using diverse conjugation chemistry. Multiple endogenous amino acids can serve as potential conjugation sites. However, to achieve more precisely ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload). A payload drug can be attached to different sites on an antibody using diverse conjugation chemistry. Multiple endogenous amino acids can serve as potential conjugation sites. However, to achieve more precisely ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. LU99 Cell ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. LK 2 Cell ...
Manufactured by:Sanquin based inAmsterdam, NETHERLANDS
Our proprietary technology for UV-induced MHC-peptide exchange is ideally suited for high-throughput screening of peptide-binding to the MHC class I complexes. Moreover, combinatorial coding enables fast finding of relevant peptide-specific cytotoxic T ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. The C106 cell line was established from a ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains. Compared to αβ T cells, γδ T cells without MHC restriction on tumor antigen recognition have strong cytotoxic effects on tumor cells. γδ T cells have been considered as wonderful effector cells for cancer immunotherapy. Creative Biolabs is an excellent expert in γδ T cell research ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Radiopharmaceutical therapies represent an effective way to treat solid cancers by using tumor targeting small molecules, peptides or biologics to deliver a cytotoxic payload that induces DNA damage in tumor cells, while limiting damage to normal and healthy tissue. Streamlined development, evaluation and clinical translation of radiopharmaceuticals requires a partner that has ...
Manufactured by:Hybrisan Ltd. based inPort Talbot Talbot, UNITED KINGDOM
Hybrisan antimicrobial technology is a platform which offers an alternative to existing technologies such as silver, compatible with a range of materials and manufacturing processes. Hybrisan antimicrobial technology is the result of extensive collaboration between industry and research ...
Manufactured by:Quay Pharma based inFlintshire, UNITED KINGDOM
We are fully equipped and accredited to manufacture a wide range of products for Phase 2 and small-scale Phase 3 trials. We provide this service to pharmaceutical and biopharmaceutical clients throughout the ...
Manufactured by:Elos Medtech. based inRosenheim, GERMANY
Medical devices demand the highest degree of safety, functionality and efficiency. A well planned and performed validation program is the basis for a safe and efficient product and a successful product approval. puracon can support you not only in setting up a product-based validation program, but also in organizing and performing the selected validation program in-house or with expert partners. ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
At Catalent, our methodologies work toward reducing the overall costs and time it takes to get your product to the clinic. With decades of experience in analytical development, we understand our clients’ needs, the current regulatory environment, and have a history of the development and qualification of analytical methods. We operate with a forward-looking methodology by deploying robust ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology's ex vivo 3D co-culture platform for Immuno-Oncology therapeutic testing. Champions Oncology has launched an innovative new platform enabling Immuno-Oncology researchers the ability to test their therapeutics in a 3D organoid assay that can mimic mechanism of action. The Autologous TIL platform is an ex vivo 3D co-culture platform developed and optimized to interrogate the ...
Manufactured by:ITM Isotope Technologies Munich SE based inGarching / Munich, GERMANY
Targeted Radionuclide Therapy (TRT) or Peptide Receptor Radionuclide Therapy (PRRT) is a medical specialty using very small amounts of radioactive compounds, called radiopharmaceuticals, to diagnose and treat various diseases, like cancer. Once injected into the patient, the radiopharmaceutical finds its way to the tumor through the bloodstream and binds to the tumor specific receptor according ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
We move your identified hits forward into in vivo testing and lead optimization. As a critical phase in your drug development journey, the hit to lead phase will determine which of your promising compounds will be characterized against your targets. With a lean ethos, InnoSer is dedicated to combining our expertise with your drug development goals in the most resource efficient way. During this ...