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Phenotyping Services In Europe
19 services found
by:OracleBio based inGlasgow, UNITED KINGDOM
Adding value to Immuno-Oncology studies with Quantitative Digital Pathology. Quantitative Digital Pathology provides deep insights into the tumor microenvironment (TME), a knowledge which is crucial for understanding the mechanism of action of new oncology immunotherapies or for investigating new biomarkers. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has developed human highly immortalized differentiated cell lines from various human tissues that show stable growth characteristics and phenotypes and have a high potential for production of complex biopharmaceuticals such as recombinant proteins, vaccines or extracellular vesicles. Creative Bioarray provides already established cell lines to get ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Our Non-Alcoholic Fatty Liver Disorder (NAFLD)/NASH in vitro Services offer a preclinical tool to test therapeutics in a human-relevant model, replicating key disease phenotypes including fibrosis and reporting clinical biomarkers to allow translatability to clinical trials. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Activated fibroblasts differentiate into myofibroblasts, a process known as fibroblast-to-myofibroblast transition (FMT). This persistent myofibroblast phenotype leads to an increased synthesis of extracellular matrix proteins, and their deposition within the lung parenchyma, causing progressive scarring, increased lung stiffness and a loss in lung function. ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Both models are iPSC derived allowing gene-edited lines to be engineered using CRISPR/Cas9 for direct comparison between WT and mutant phenotypes after differentiation. Targeted mutations can model retinopathies, more specifically monogenic inherited retinopathies such as retinitis pigmentosa (RP), Stargardt disease, Usher’s syndrome and Leber congenital ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Blood collection, shipping and processing is often the first point of failure for cell based immunology assays, such as ELISpot, flow cytometric phenotyping and functional cell based assays. When these assays are planned as part of multi-center clinical trials, setting up processes for collecting processing, shipping, preserving blood incorrectly can have catastrophic ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Drug design is engineering at the molecular scale. Every position of every atom and every bond determines the future success of a ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
by:Indica Labs Inc. based inAlbuquerque, NEW MEXICO (USA)
Leveraging our own image analysis and image management solutions, HALO, HALO AI and HALO Link, as well as the expertise of our PHARMA SERVICES and algorithm development teams, we offer a wide range of analysis services to pharmaceutical, contract research organizations and research institutes around the world. Whether you require an end-to-end solution or à la carte analysis services, we ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
At Catalent, our methodologies work toward reducing the overall costs and time it takes to get your product to the clinic. With decades of experience in analytical development, we understand our clients’ needs, the current regulatory environment, and have a history of the development and qualification of analytical methods. We operate with a forward-looking methodology by deploying robust ...
by:Oncodesign based inDijon, FRANCE
EXPLORE, a new service to identify and validate therapeutic targets, primarily cancer treatments – an area of expertise and excellence at Oncodesign to discover and investigate preclinical proofs of concept involving a wide variety of different approaches and anti-cancer mechanisms of action. EXPLORE, is the combination of our OncoSNIPER platform and a tailored and well established ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology's ex vivo AML co-culture platform for Immuno-Oncology therapeutic testing. Champions Oncology has launched an innovative new platform enabling Acute Myeloid Leukemia (AML) researchers the ability to better understand their therapeutic mechanism of action. The Autologous AML Platform is an ex vivo co-culture assay developed and optimized to interrogate the responses of your ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Only with continual feedback between experiment and prediction can machine learning models be refined and deliver against complex therapeutic ...
by:Oncodesign based inDijon, FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign has been a player known for its experience and ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
The fastest and most comprehensive genetic testing available for newborns, infants and children less than 24 months old in intensive care. CentoICU – Genetic Testing When Every Moment Counts. Up to one-third of all babies and children admitted to the ICU have a genetic disease. For many patients, early identification can make a difference in their immediate and long-term ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics is developing Adoptive Cell Therapies, which are designed to leverage the power of T cells to actively infiltrate tumor tissue and kill tumor cells in a specific and serial ...