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Phenotyping Equipment Supplied In Europe
63 equipment items found
by:EraCal Therapeutics Ltd. based inSchlieren, SWITZERLAND
EraCal’s platform enables unbiased and large-scale in vivo drug discovery in zebrafish larvae. The journal Science Advances published part of EraCal’s translational proof of concept. Such phenotypic strategies are capable of identifying novel mechanisms of actions and, consequently, are a prime choice to discover first-in-class ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
The CentoPharma platform provides intelligent access to our comprehensive data repository that combines phenotype, genotype and biochemistry information with epidemiological data and clinical information from a global cohort originating from more than 120 countries. Dynamic search criteria enable the targeted compilation of individual customized cohorts based on desired ...
Manufactured by:Creative Diagnostics based inShirley, NEW YORK (USA)
In 1957, Conrad Waddington coined a term “Epigenetics” to describe how a gene interacts with its surrounding to produce a phenotype. Since then, people use Epigenetic to define a phenomenon that changes the final outcome of gene expression without changing the underlying DNA sequence. In recent decades, the mechanism of Epigenetics can be mainly classified into three groups: DNA ...
by:STALICLA based inGeneve, SWITZERLAND
DDU validates ASD phenotype groups and drug candidates through observational studies and investigational trials. DDU combines expertise in operations, medicine, drug and clinical development, to bring STALICLA’s clinical-stage treatment options closer to ...
Manufactured by:The Menarini Group based inFlorence, ITALY
FLT3 internal tandem duplication (FLT3-ITD) is one of the most common genetic lesions in acute myeloid leukemia patients (AML) and is associated with a poor prognosis. PIM kinases are thought to be one of the major drivers of the resistance phenotype to FLT3 inhibitors and their inhibition in relapsed samples restores cell sensitivity to FLT3 inhibitors these ...
Manufactured by:Sartorius CellGenix GmbH based inFreiburg, GERMANY
CellGenix GMP DC is an optimized, serum-free medium used for the generation of human dendritic cells (DCs). It promotes high yields of mature dendritic cells with the desired ...
Manufactured by:MTC INVITRO DIAGNOSTICS AG based inBensheim, GERMANY
MTC offers a complete product line of Bloodgrouping reagents. Conventional liquid reagents for blood grouping of AB0 and Rh phenotyping with different clone lines, Bloodgrouping reagents for rare bloodgroups from monoclonal and polyclonal origin with a wide selection of rare antisera blood types. Blood typing reagent red cell products for AB0 reverse typing, ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Disease specific in vitro models for your research. Skimune AD: Our advanced Skimune® model stimulated to demonstrate an AD phenotype through addition of inflammatory cytokines and autologous immune ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
FocuSCOPE is a high-throughput single cell multi-omics sequencing solution that can detect both genetic variants and transcriptome from the same single cells. Thus, FocuSCOPE® provided a tool to decipher the connection between genotype and phenotype at single cell ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Our Non-Alcoholic Fatty Liver Disorder (NAFLD)/NASH in vitro Services offer a preclinical tool to test therapeutics in a human-relevant model, replicating key disease phenotypes including fibrosis and reporting clinical biomarkers to allow translatability to clinical trials. ...
Manufactured by:Microbiotica Limited based inLittle Chesterford, UNITED KINGDOM
Thus metagenomics routinely can classify only 50 % of gut bacterial sequences, meaning that a very large fraction of gut bacteria are not seen, compromising the association between particular bacteria and biology or patient ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Gibco CTS OpTmizer Pro SFM is a novel medium, developed for the growth and expansion of human T lymphocytes (e.g., CD4+, CD8+, polyclonal cells, or antigen specific T cells) used in allogeneic cell therapies. CTS OpTmizer Pro SFM improves central memory phenotype and cell growth by shifting the cell’s metabolism. The result is a larger population of central memory cells in ...
Manufactured by:Rarecells Diagnostics SAS based inParis Cedex 06, FRANCE
The solution relies on the larger size of all types of CTCs as compared to the majority of leukocytes. ISET system successfully captures CTCs that are presenting, by definition, heterogeneous phenotypic profiles. ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Our team can manufacture astrocytes at scale from the iPSC that best fits your project or work with off-the-shelf Ncyte Astrocytes to model relevant disease-phenotypes and support your drug discovery campaigns. ...
Manufactured by:Elthera AG based inSchlieren, SWITZERLAND
L1CAM expression increases the malignancy of these tumors by promoting cellular proliferation, metastatic spread, tumor angiogenesis, and resistance to chemotherapy. Accordingly, L1CAM-positive tumors show a highly malignant and invasive phenotype, leading to a poor prognosis for the affected patients. ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Assessment of immune activation: Alcyomics has a wide range of cell phenotypic services for your research needs, to benefit both drug discovery and validation. With our in-house state-of-the-art instrumentation, we can analyse and deliver accurate analyses of T-cell proliferation responses and perform multiplex cytokine analysis. ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
In addition, many epithelial tumours, such as breast, ovarian, gastrointestinal and prostate switch from expression of cytokeratin to vimentin during metastasis in a process known as epithelial mesenchymal transition (EMT). This change in phenotype enables the cell to become mobile and metastasize to new locations in the ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
These glycan structures form the “glycome” and play an integral role in cell-to-cell and cell-to-matrix interactions through modulation of adhesion and cell trafficking. Glycosylation is increasingly recognised as a modulator of the malignant phenotype of cancer cells, where the interaction between cells and the tumour micro-environment is altered to facilitate ...
by:STALICLA based inGeneve, SWITZERLAND
STALICLA is advancing a robust pipeline of both proprietary and partnered therapeutic ...
Manufactured by:ViennaLab Diagnostics GmbH based inVienna, AUSTRIA
Genetic variants of the drug-metabolizing enzyme CYP2C9 lead to high inter-individual dose response variability of certain drugs, in particular coumarin-based anticoagulants. The CYP2C9 mpx RealFast™ Assay allows for the simultaneous detection of CYP2C9*2 and CYP2C9*3 variants exhibiting impaired enzyme ...