- Home
- Services
- north america
- active pharmaceutical ingredient
Show results for
Refine by
Active Pharmaceutical Ingredient Services In North America
33 services found
by:Bureau Veritas North America, Inc. based inNew York, NEW YORK (USA)
What are APIS and should I Be Concerned about Them? Active pharmaceutical ingredients (APIs) are defined as any substance or a mixture of substances that when used in the production of a drug, becomes an active ingredient in the drug product. Unlike most chemical hazards in the workplace for which health effects ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
MRTX0902 is a potent SOS1 inhibitor which can be used for the therapeutic intervention of KRAS-driven (Kirsten rat sarcoma virus driven) cancers. Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with KRAS being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in human cancers and is present in 35% of lung adenocarcinomas ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Acetazolamide is a white to yellowish-white fine crystalline powder that is slightly soluble in acetone, insoluble in chloroform, diethyl ether and carbon tetrachloride. The chemical name of it is 2-acetamido-1,3,4-thiadiazole-5-sulfonamide. Acetazolamide is a first-generation carbonic anhydrase (CA) inhibitor, which is most commonly used in the treatment of glaucoma. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Sulfamethoxazole, a sulfanilamide, is a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase and inhibits the conversion of PABA to dihydrofolic acid. Inhibition of this pathway ultimately prevents the synthesis of folate that is a critical role during DNA synthesis. Therefor, sulfamethoxazole can inhibit the growth and replication of ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Chlorquinaldol is monohydroxyquinoline, or quinolin-8-ol that is substituted by a methyl group at position 2 and chlorine at positions 5 and 7. It is a solid insoluble in water and the chemical name of chlorquinaldol is 5,7-dichloro-2-methyl-8-hydroxyquinoline. Chlorquinaldol is an antimicrobial agent used in the treatment of bacterial vaginosis. Alfa Chemistry offers high quality chlorquinaldol. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cyclophosphamide: Cyclophosphamide, also known as cytophosphane, appears as a white to almost white crystalline powder with a slightly bitter taste. The chemical name of it is p-[N,N-bis-(2-chloroethyl)]-1-oxo-3-nitrogen-2-phosphocyclohexane-p-oxide monohydrate. Cyclophosphamide is a synthetic alkylating agent chemically related to nitrogen mustard with antineoplastic and immunosuppressive ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Methotrexate, one of the earliest cancer chemotherapy agents, which is extensively used in the treatment of cancer, including breast cancer, leukemia, lung cancer, lymphoma, osteosarcoma and so on. The efficacy of methotrexate mainly due to its inhibitory effect on dihydrofolate reductase (DHFR)[1]. DHFR catalyzes the conversion of dihydrofolate to the active tetrahydrofolate that is needed for ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Benzhexol hydrochloride is a class of antimuscarinic drug with the chemical name (±)-a-cyclohexyl-1-phenyl-3-(1-piperidinyl)-propanol hydrochloride. It was approved by the FDA for the treatment of Parkinson's disease (PD) in the United States in 2003. By improving muscle stiffness, benzhexol hydrochloride allows the body to move normally. Alfa Chemistry offers high quality benzhexol ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963.7 It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.5,8 Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cytarabine Hydrochloride: Cytarabine hydrochloride is a white to off-white crystalline with the chemical name 1-β-D-arabinofuranosyl-4-amino-2(1H)-pyrimidinone hydrochloride. Cytarabine hydrochloride is used in chemotherapy for white blood cell cancers, especially acute myeloid leukemia (AML). ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosamine sulfate, in the human body is secreted by mast cells and naturally exists in the blood. Heparin sodium Chemicalbook can prevent platelet aggregation and destruction, inhibit the transformation of fibrinogen into fibrin monomer, inhibit the ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Ancitabine Hydrochloride: Ancitabine hydrochloride is a white needle-like crystal or crystalline powder that is freely soluble in water, slightly soluble in methanol and ethanol, and almost insoluble in ether, benzene and chloroform. The chemical name of it is 2-methanolyl 2,3,3a,9a-tetrahydro-3hydroxy-6-imino-6H furan-(2',3',4,5)-oxazole(3,2a) pyrimidine hydrochloride. Ancitabine hydrochloride ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Meropenem with sodium carbonate is a salt form of Meropenem, a β-lactam antibiotic of the carbapenem subclass that has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci. This compound demonstrates the ability to also affect strains of 11 species of streptococci. Mechanistic studies suggest that Meropenem′s antimicrobial activity is based on its high ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Active Pharmaceutical Ingredients (APIs) are substances or mixtures employed in the production of drugs. They have pharmacological effects or directly contribute to diagnosing, treating, mitigating symptoms, controlling, or preventing diseases, in addition to influencing the structure or function of the body. ...
Manufactured by:Nephron Pharmaceuticals Corporation based inWest Columbia, SOUTH CAROLINA (USA)
Our team of experts ensure every substance that enters and exits our facility is safe for use. When active pharmaceutical ingredients arrive on site, our quality assurance department samples and reviews the ingredients before they are released for use. We perform another quality check after we formulate products, reviewing ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Among them, physical modification methods include eutectic method in addition to nano-grinding and micronization. Co-crystal refers to the crystal formed by the combination of active pharmaceutical ingredient (API) and co-crystal former (CCF) under the action of hydrogen bonds or other non-covalent bonds, wherein the pure state of API and CCF is ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
Bioavailability of active pharmaceutical ingredients (APIs) is a key factor in successful drug development. By choosing API physical modification services, we can support your solution, improve poor water solubility, and control optimized release characteristics to help increase your productivity and return on investment. ...
Manufactured by:Regis Technologies Inc. based inMorton Grove, ILLINOIS (USA)
Expedite your discovery-to-market timeline by partnering with Regis Technologies to produce your Active Pharmaceutical Ingredients (APIs) and intermediates. We are committed to advancing your projects from initial process development, scale-up development through final validation and commercial manufacturing. Partner with Regis to bring your ...
Manufactured by:CD Formulation based inShirley, NEW YORK (USA)
CD Formulation can provide you with dissolution profiles of active pharmaceutical ingredients in various solvents (including inorganic solvents with different pH values, organic solvents, simulated intestinal juice or gastric juice, and other solvents) according to your needs. In addition, our scientists specialize in providing solubility ...
Manufactured by:Ceutical Labs based inFlower Mound, TEXAS (USA)
There are several distinct markets that are served by the Analytical Testing Division. They include Pharmaceutical, Nutraceutical, Medical Device, API (Active Pharmaceutical Ingredient), NDI (New Dietary Ingredient) and Post Sterilization Testing. Two of these categories, API and NDI require additional ...