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Neurodegenerative Services In North America
21 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Amyotrophic lateral sclerosis is a neurodegenerative disorder leading to loss of voluntary muscle movement, paralysis, and eventually death. There is now an urgent need for the development of effective treatment for ALS. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Neurodegenerative diseases (NDs) comprise a diverse set of pathological processes involving progressive neuronal dysfunction, degeneration, and death, leading to incurable and debilitating diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in neurodegeneration-related mitochondria ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene provides the fractionated mitochondrial magnetic separation (FMMS) method to increase the production of brain-derived mitochondria compared with the UC method and can better detect mitochondrial damage in the central nervous system injury and neurodegenerative ...
Manufactured by:RareStone Group based inShanghai, CHINA
Rare neurological diseases include developmental defects of the nervous system, genetic and metabolic diseases, neuroimmune diseases, neurological tumors, special types of infectious diseases of the nervous system, neurodegenerative diseases, and neuromuscular diseases. At present, more than 7,000 rare diseases have been found in humans, about 60% of which are neurological ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of human MS as it is especially useful to investigate neuroinflammatory pathways and often serves as a "proof-of-principle" model for the efficacy of novel treatment strategies. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as ...
Manufactured by:Neurodigitech, LLC based inEncinitas, CALIFORNIA (USA)
The NDT teams in specialized in both non-GLP and GLP compliant pre-clinical assessments of CNS disease therapeutics using a variety of biomarkers, including histology, immunohistochemical and histochemical methods. In particular, NDT is dedicated to custom-designed neuropathological assessments for the neurodegenerative diseases, such as Alzheimer's, Parkinson's, ALS, and brain ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary gene-editing technology that can precisely modify the genomic sequence. ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Biomarker specializations include Alzheimer’s and dementia, Parkinson’s and basal ganglia disorders, mood disorders and other neurodegenerative and neuropsychiatric diseases. ...
by:IOS Press based inAmsterdam, NETHERLANDS
Here you will find information about our ejournals and ebooks in terms of collections/subject areas, pricing, terms and conditions and a FAQ ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative diseases, but also provide a unique chemical knockdown tool for biological research in a catalytic, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human iPSC-derived Microglia provide a reproducible, physiologically-relevant model in an easy-to-use, assay-ready format for investigating neuroglia involvement in neurodegeneration and neurodevelopment. We also offer a fully optimized serum-free Microglia Maintenance Medium to promote and support the maintenance of microglia. The method for generating iPSC-derived microglia mimics the in vivo ...
Manufactured by:vivoVerse Inc. based inAustin, TEXAS (USA)
C. elegans is recognized as a useful alternative in vivo model. The vivoChip® enables the use of C. elegans for high-content, multi-parametric analysis of neurodegeneration phenotypes from high-resolution fluorescence images of neurons. To demonstrate our unique capabilities, we studied dendritic neurodegeneration of dopaminergic neurons in C. elegans induced by a well-accepted neurotoxicant, ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Among the many experimental models, C. elegans is particularly effective because of its morphological, behavioral, and genetic advantages. The C. elegans model is suitable for the research of bioactive compounds in various fields, such as anti-aging research, anti-neurodegeneration, anti-obesity, anti-infection and intestinal health. Besides those, the technological development of C. elegans in ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Autophagy is a catabolic mechanism which sequesters cytoplasmic components for lysosomal-mediated degradation, including protein inclusions and damaged organelles. Autophagy has an important role in diverse physiological processes such as adaptation to nutrient starvation, cell death, embryonic development, energy metabolism, and antigen presentation, among other events. Moreover, autophagy has ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knockout mice are animal models that have been genetically modified to delete or inactivate a specific gene. The term ‘knockout’ refers to knocking out the functionality of the target gene. These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
Manufactured by:Arthus Biosystems, LLC based inChantilly, VIRGINIA (USA)
Our team of scientists performs integrated research, development, and technical support to market the antibodies against S-adenosylmethionine, or the SAM molecule. We are dedicated to develop several formats of immunoassays to detect SAM and S-adenosylhomocysteine (SAH) from biosamples efficiently. Immunoassays have been approved to be easy to use without requiring costly equipment, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostanoids, also known as eicosanoids, are a family of signaling molecules produced and secreted by various types of cells under both normal and pathological conditions. In the human body, these metabolites are excreted into body fluids such as plasma and urine. The precursors of prostanoids are 20-carbon polyunsaturated fatty acids (PUFAs) like arachidonic acid (C20:4), which are esterified in ...