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Neurodegenerative Equipment Supplied In North America
106 equipment items found
by:Vaxxinit based inDallas, TEXAS (USA)
We are developing an anti-tau product candidate that has the potential to address multiple neurodegenerative conditions, including AD, by targeting abnormal tau proteins alone and in potential combination with other pathological proteins such as Aβ to combat multiple pathological processes at ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
mGlu3 PAM for the treatment of neurodegenerative disorders. We are developing mGlu3 PAM as a novel orally available treatment for neurodegenerative disorders. We are currently optimizing multiple chemical series of highly selective mGlu3 PAMs, with compounds in early lead optimization. ...
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Manufactured by:Bertin Technologies based inMontigny-le-Bretonneux, FRANCE
Bertin Bioreagent offers primary and secondary antibodies for laboratories. As essential tools, they are particularly versatile when properly ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Protein misfolding is the root of many diseases, including lysosomal storage disorders and neurodegenerative ...
by:LIXTE Biotechnology Holdings, Inc. based inPasadena, CALIFORNIA (USA)
We have also developed another class of compounds that are novel histone deacetylase inhibitors (HDACi). Designated as our LB-200 series of compounds, these have potential use in the prevention and treatment of neurodegenerative diseases. The series has the potential to be the most effective in its class and may be useful for the treatment of chronic hereditary diseases, such as ...
Manufactured by:Woolsey Pharmaceuticals, Inc. based inNew York City, NEW YORK (USA)
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are rare neurodegenerative disorders associated with the accumulation of insoluble deposits of predominantly 4 microtubule binding domain repeat (4R) tau protein in specific brain regions, mainly in the absence of other pathogenic proteins including β-amyloid, which is found in Alzheimer’s ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Parkinson’s disease is a neurodegenerative disorder that affects more than 6 million people worldwide. In most cases, the exact cause of Parkinson’s disease is unknown; however, mutations in GBA1, the gene that encodes the beta-glucocerebrosidase (GCase) enzyme, have been tied to the disease. ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Krabbe disease is a severe neurodegenerative disorder caused by mutations in GALC, the gene that encodes the galactosylceramidase (GALC) enzyme. These mutations cause GALC misfolding and dysfunction, which leads to the toxic buildup up fats in the central nervous system (CNS) and ultimately leads to the demyelination and death of neurons. ...
Manufactured by:MuseChem based inPaoli, PENNSYLVANIA (USA)
Methylene Blue also has antimicrobial properties, making it useful in treating infections. Additionally, it is studied for its neuroprotective effects in neurodegenerative diseases and its potential as a photosensitizer in cancer therapy. Its wide range of uses makes it a versatile compound in clinical and research ...
Manufactured by:AVEO Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
Scientific literature has implicated the Notch 3 receptor pathway in multiple diseases, including cancer, cardiovascular diseases and neurodegenerative ...
Manufactured by:Alkahest, Inc. based inSan Carlos, CALIFORNIA (USA)
Alkahest, with its partner Grifols, is developing lead clinical candidates, GRF6019 and GRF6021, as potential treatments for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease with cognitive impairment. Designed to safely replenish regenerative positive chronokines that decrease with age, GRF6019 and GRF6021 are highly selected human ...
Manufactured by:MagQu LLC USA based inSurprise, ARIZONA (USA)
When tau proteins become defective, It will result in the self-assembly of tangles in brain and increased some neurodegenerative diseasesincluding Alzheimer’s disease (AD)?Pick's disease?Parkinson's disease (PD)?Progressive supranuclear palsy(PSP) and Corticobasal degeneration ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length ...
Manufactured by:KinesisDx based inBrea, CALIFORNIA (USA)
Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length ...
Manufactured by:Woolsey Pharmaceuticals, Inc. based inNew York City, NEW YORK (USA)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. ALS is part of a wider group of disorders known as motor neuron diseases. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body, governing voluntary movements and muscle control. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's ...
Manufactured by:Caprico Biotechnologies, Inc. (CBI) based inNorcross, GEORGIA (US) (USA)
EAPII has been demonstrated to have promiscuous protein associations, broad responsiveness to various extracellular signals, and pleiotropic functions in the development of human diseases including cancer and neurodegenerative ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Nervonic acid exerts anti-inflammatory activity by inhibiting NF-κB signaling. Nervonic acid can be used in the study of neurodegenerative ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
DUB-IN-3 (compound 22c) is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. DUB-IN-3 is promising for research of cancer, neurodegenerative diseases, inflammation, viral infection and cardiovascular ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
THX-B is a potent and non-peptidic p75NTR (neurotrophin receptor p75) antagonist. THX-B can be used in the research of diabetic kidney disease, neurodegenerative and inflammatory ...