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Cancer Cell Articles & Analysis

270 articles found

Abandoned oncology drugs -Identifying new indications using active machine learning and a biobank of patient derived dissociated tumor cells (DTCs)

Abandoned oncology drugs -Identifying new indications using active machine learning and a biobank of patient derived dissociated tumor cells (DTCs)

Many oncology drugs have been abandoned by pharmaceutical companies due to poor performance in phase I, II, or III clinical trials. These drugs represent untapped potential treatments for indications outside of those initially investigated. With research and development costs for a single new drug estimated between $2–3 billion, abandoned drugs represent an opportunity to bring drugs to ...

ByPredictive Oncology Inc.


Repurposing Drugs for Cancers of the Breast, Colon, and Ovary using Active Machine Learning and Biobank of DTC’s

Repurposing Drugs for Cancers of the Breast, Colon, and Ovary using Active Machine Learning and Biobank of DTC’s

Population growth, aging populations and increases in cancer incidence have necessitated new approaches to identifying effective treatments. ...

ByPredictive Oncology Inc.


Immortalized Human Ovarian Epithelial Cells-SV40: A Key Tool in Cancer Research

Immortalized Human Ovarian Epithelial Cells-SV40: A Key Tool in Cancer Research

Human ovarian epithelial cells play a crucial role in ovarian function and have become a significant focus in cancer research, specifically ovarian cancer. ...

ByCreative Bioarray


What is the Role of tRNA Methylation Modification in the Cell Cycle?

What is the Role of tRNA Methylation Modification in the Cell Cycle?

Post-transcriptional modifications of RNA molecules include methylation, acetylation deamination, isomerization, glycosylation, thiolation and pseudouracil modification among other types. Methylation represents the predominant post-transcriptional modification found within transfer RNA (tRNA) molecules. tRNA methylation has maintained its evolutionary conservation while also exhibiting dynamic ...

ByCreative Diagnostics


CRISPR/Cas9 Lentivirus Production Service: Revolutionizing Gene Editing

CRISPR/Cas9 Lentivirus Production Service: Revolutionizing Gene Editing

Unlike other viral vectors, lentiviruses can transduce both dividing and non-dividing cells, broadening the scope of potential applications. This property is particularly beneficial for targeting tissues that are not actively dividing, such as neurons and certain types of stem cells. ...

ByCreative Biogene


Adenovirus Production Services: A Comprehensive Overview

Adenovirus Production Services: A Comprehensive Overview

Adenoviruses are a group of viruses that have gained significant attention in recent years, particularly in the fields of gene therapy, vaccine development, and cancer treatment. With their ability to deliver genetic material into cells effectively, adenoviruses serve as valuable vectors in various biomedical applications. ...

ByCreative Biogene


Monodispersed PEG Linkers Enhance Antibody–Drug Conjugates (ADCs)

Monodispersed PEG Linkers Enhance Antibody–Drug Conjugates (ADCs)

Antibody-drug conjugates (ADCs) combine potent small-molecule drugs with monoclonal antibodies for targeted cancer therapy. A major challenge is loading enough drug onto each antibody without compromising solubility or circulation time. ...

ByBiopharma PEG Scientific Inc


Understanding the BCL2 Gene Family: Function, Research Highlights, and Medical Relevance

Understanding the BCL2 Gene Family: Function, Research Highlights, and Medical Relevance

It belongs to a larger BCL2 gene family, which includes both pro-apoptotic and anti-apoptotic proteins that maintain a delicate balance between cell survival and cell death. Dysregulation of this gene family is implicated in a variety of diseases, most notably cancer. ...

ByCreative BioMart


Exploring Popular API Types: A Comprehensive Overview

Exploring Popular API Types: A Comprehensive Overview

These specialized compounds often target cancer by interfering with cell division, signal transduction, or angiogenesis processes. Modern oncology APIs include targeted therapies like kinase inhibitors and monoclonal antibodies that precisely attack cancer cells while minimizing damage to healthy tissues. The manufacturing of ...

ByAlfa Chemistry


Innovative Preclinical Alfa Cytology alfaCAR-T Solutions: Revolutionizing the CAR-T Development Platform

Innovative Preclinical Alfa Cytology alfaCAR-T Solutions: Revolutionizing the CAR-T Development Platform

Cancer treatment has witnessed transformative advancements over the past few decades, notably with the emergence of CAR-T (Chimeric Antigen Receptor T-cell) therapy. This revolutionary therapy harnesses the body's immune system by genetically engineering T-cells to target and destroy cancer cells. Among the ...

ByAlfa Cytology


Alfa Cytology Introduces Specialized Therapeutic Development Services Targeting FAP for Precision Oncology Treatments

Alfa Cytology Introduces Specialized Therapeutic Development Services Targeting FAP for Precision Oncology Treatments

The conventional treatment approaches fail to accurately target cancer cells, which results in numerous adverse effects while diminishing treatment success. ...

ByAlfa Cytology


Antibody Drug Design: Advancements and Innovations

Antibody Drug Design: Advancements and Innovations

Researchers are increasingly focused on engineering antibodies that can selectively target specific cancer cells or diseased tissues while minimizing off-target effects. ...

ByCreative Biogene


Understanding Circulating Tumor Cells (CTCs) and the Role of FISH

Understanding Circulating Tumor Cells (CTCs) and the Role of FISH

Circulating Tumor Cells, or CTCs, are cancer cells that have shed from the primary tumor and enter the bloodstream, where they can travel and potentially lead to metastasis. ...

ByCreative Bioarray


Research on Platelet Drug Delivery System

Research on Platelet Drug Delivery System

When PD-1 molecules on platelets interact with anti-PD-1 on tumor cells they release drugs that eliminate regulatory T cells while boosting CD8+ T cell functions which helps decrease tumor recurrence and metastasis after surgery. ...

ByCD Bioparticles


Alfa Cytology Introduces Full-Scale ADCs Development Services Focused on Cancer Therapy

Alfa Cytology Introduces Full-Scale ADCs Development Services Focused on Cancer Therapy

The pioneering initiative represents a major advancement in targeting cancer treatments to destroy malignant cells effectively while reducing damage to healthy tissues. ...

ByAlfa Cytology


Advancing Cancer Treatment: The Role of Radioactive Drug Conjugate Development Services and Pre-Clinical Analysis Services for RDCs

Advancing Cancer Treatment: The Role of Radioactive Drug Conjugate Development Services and Pre-Clinical Analysis Services for RDCs

These innovative therapeutic agents combine the targeting capabilities of antibodies with the cytotoxic effects of radioactive isotopes, providing a powerful strategy for precision cancer treatment. Understanding Radioactive Drug Conjugates Radioactive drug conjugates are engineered to deliver radiation directly to cancer cells while sparing ...

ByAlfa Cytology


ADC Development and Production: Innovations and Best Practices

ADC Development and Production: Innovations and Best Practices

The monoclonal antibody is designed to bind specifically to cancer cells, ensuring that the toxic drug is delivered directly to the tumor, thereby minimizing damage to healthy cells. ...

ByCreative Biogene


Hydroxyapatite: Revolutionizing Biomedical and Environmental Applications

Hydroxyapatite: Revolutionizing Biomedical and Environmental Applications

For instance, HA-based scaffolds are being developed to promote bone regeneration, while HA nanoparticles are engineered to deliver drugs directly to cancer cells, minimizing side effects. l Nanotechnology and Surface Engineering The synthesis of nano-sized HA particles has opened new doors for precision medicine. ...

ByMatexcel


Introduce the Use of Radiopaque Markers in Modern Medicine

Introduce the Use of Radiopaque Markers in Modern Medicine

One of these impressive solutions is radiopaque markers – small devices used to diagnose and treat a variety of conditions, ranging from cardiovascular problems to cancer. Not only do they help doctors better understand what’s going on inside patients’ bodies, but they also provide an important bridge between traditional medicine and modern alternatives by ...

ByEdgetech Industries LLC


BIOPHARMA PEG Showcases DSPE-PEG-Mannose: A Cutting-Edge Polymer for Drug Delivery and Biomedical Applications

BIOPHARMA PEG Showcases DSPE-PEG-Mannose: A Cutting-Edge Polymer for Drug Delivery and Biomedical Applications

Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose is composed of three key ...

ByBiopharma PEG Scientific Inc

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