Chemotherapeutic Agent Articles & Analysis
10 articles found
Leukocyte membrane-encapsulated NPs could circumvent phagocyte conditioning, delaying the mononuclear macrophage system's infiltration, selectively binding to the site of inflammation, and encouraging the chemotherapeutic agent to transit through the endothelial cell, bypass the lysosomal pathway, accumulate more drugs in tumour tissue and extend ...
Nanobodies can be engineered to specifically target tissues or cells of interest by conjugating them to therapeutic agents. This targeting ability minimizes off-target effects and increases the efficacy of the drug. For example, nanobodies have been successfully used to deliver chemotherapeutic agents to tumor cells, resulting in improved cancer ...
These assays are used to evaluate the efficacy of chemotherapeutic agents by measuring their ability to induce apoptosis in cancer cells. ...
Persistent activation of NF-κB can also lead to anti-apoptotic cell death and resistance to the apoptosis-inducing effects of chemotherapeutic agents. The above several NF-κB-mediated cancer formation mechanisms can coordinate with each other and interact at different signaling levels to jointly promote tumorigenesis and progression. ...
Applications of Cell-Penetrating Peptides Treatment of tumors CPPs can use their membrane-penetrating effects to carry chemotherapeutic drugs or biologic agents into the body, and release the carrier in the cytoplasm or target action sites to maximize the effectiveness of the treatment of the resulting tumor cells. Dubikovskaya et al. linked the penetrating ...
There was no concern from radiology or oncology review that the fractures were metastatic in nature; rather bilateral insufficiency fractures likely secondary to the chemotherapeutic agents and/or radiation ...
Liposomes vary in size, composition and charge and can be used as carriers for a wide range of drug molecules, such as chemotherapeutic agents, antimicrobial and antiviral drugs, antiparasitic drugs, genetic material, vaccines, therapeutic proteins, and anti-inflammatory agents. ...
Treatment of Tumors CPPs can use their membrane-penetrating effects to carry chemotherapeutic drugs or biologic agents into the body and release the carrier in the cytoplasm or target action sites to maximize the effectiveness of the treatment of the resulting tumor cells. Through a biolysable disulfide ligand, the cell-penetrating peptide R8 can be linked to ...
Omega-3 PUFA may exert anti-cancer effects by inhibiting tumor cell proliferation and inducing apoptosis, and by promoting the sensitivity of tumor cells to chemotherapeutic agents. Creative Proteomics provides fatty acid analysis services. ...
These Listeria monocytogenes remain in tumor tissue and are cleared by healthy tissue, activating T cells to kill the tumor, which, when combined with chemotherapeutic agents like gemcitabine, rapidly cleared pancreatic cancer cells, reduced cancer metastasis by 87%, and dramatically extended life. ...