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Computational Biology Articles & Analysis

12 articles found

The Journey of Drug Design: From Computational Modeling to Therapeutic Innovation      

The Journey of Drug Design: From Computational Modeling to Therapeutic Innovation    

The development of new and effective drugs is a complex and multifaceted process that requires the collaboration of scientists from diverse fields, including chemistry, biology, and computational modeling. At the heart of this endeavor lies the art of drug design - the strategic and methodical approach to creating molecules that can effectively target and ...

ByCD ComputaBio


Drug Discovery: Unraveling the Mysteries of Therapeutic Agents

Drug Discovery: Unraveling the Mysteries of Therapeutic Agents

The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. At the heart of this endeavor lies the intricate relationship between drugs, their targets, and the diseases they aim to treat. ...

ByCD ComputaBio


In Silico Sorcery: Envisioning Tomorrow's Drugs Today with Computational Design

In Silico Sorcery: Envisioning Tomorrow's Drugs Today with Computational Design

Through its integration of computer science, chemistry, biology, and physics, CADD has proven to be a pivotal force in driving the efficiency and precision of drug discovery processes. Understanding the Landscape of Computer-Aided Drug Design (CADD) Computer-Aided Drug Design, abbreviated as CADD, constitutes a ...

ByCD ComputaBio


Understanding Drug-Disease Relationship Analysis: A Key to Drug Discovery

Understanding Drug-Disease Relationship Analysis: A Key to Drug Discovery

Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the fascinating world of drug-disease relationship analysis, an essential component of drug discovery, ...

ByCD ComputaBio


National Institutes of Health – Perinatology Research Branch - Case Study

National Institutes of Health – Perinatology Research Branch - Case Study

The Perinatology Research Branch (PRB) is the only Clinical Branch in the Division of Intramural Research (DIR) of the National Institutes of Health (NIH) to focus its research on human pregnancy and unborn children. It is currently housed at the Detroit Medical Center in Detroit, Michigan through a service contract. The Branch has thrived in this environment, earning a national and international ...

ByAdvaita Bioinformatics


Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

Recently, Professor Yi Wen's research group and Professor Zhou Ruhong's research group from the School of Life Sciences, Zhejiang University jointly published a research paper titled: O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1 in Nature Chemical Biology. This study revealed the molecular mechanism of O-GlcNAc glycosylation regulating ...

ByCD BioGlyco.


Adaptive MRD Chief Commercial Officer Nitin Sood Shares How His Personal Journey Has Shaped His Career Path

Adaptive MRD Chief Commercial Officer Nitin Sood Shares How His Personal Journey Has Shaped His Career Path

Some of my earliest memories are of accompanying her to medical school classes, which inspired me to eventually pursue a PhD in molecular biology and biochemistry. My studies brought me to the U.S., where my interests shifted towards computer science and after school, I landed a role where I could apply both my software engineering and molecular ...

ByAdaptive Biotechnologies


A Computer Scientist`s Quest for Meaningful Work

A Computer Scientist`s Quest for Meaningful Work

As a 17-year-old, of course, I wanted to be cool, so I decided to pursue computer science and engineering rather than medicine. I was one of few classmates who had an email address, but had only gotten my first computer a number of days before school started. ...

ByRecursion


90 Days as a Recursionaut

90 Days as a Recursionaut

For almost a decade, I have wanted to work in the field of computational biology. I wanted to learn and grow in that space, and always hoped to work at a place where my contributions could impact a greater cause. ...

ByRecursion


New blood-based CRC test is more than 90% accurate, study says

New blood-based CRC test is more than 90% accurate, study says

The test uses single target sequence analyses of multiomics markers, computational biology and machine learning. "We have built a test that can 'read' cancer’s tissue-specific signal in blood on a fragment level," Universal Diagnostics' managing director, Christian Hense, said. ...

ByUniversal Diagnostics SL


Dr Parag Mallick in conversation with Adam M Hill. `Extra Time` podcast.

Dr Parag Mallick in conversation with Adam M Hill. `Extra Time` podcast.

Having originally trained as an engineer biochemist, Parag's research is diverse and spans computational and experimental systems biology, cancer biology, and nanotechnology. ...

ByOncimmune Holdings PLC


Identification and analysis of epitope-based malarial vaccine targets using computational biology

Identification and analysis of epitope-based malarial vaccine targets using computational biology

Malaria is a vector-borne infectious disease caused by protozoan parasite of the genus Plasmodium. The malaria vaccine which has been studied is designed to induce immunity to the sporozoite and to kill sporozoite-infected liver cells. A combination of bioinformatics approach and computational tools are used to screen and select antigen sequences as potential T-cell epitopes of supertype human ...

ByInderscience Publishers

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