In Vivo System Articles & Analysis
6 articles found
In the fast-evolving landscape of biotechnology and systems biology, understanding the dynamic processes that sustain life at a cellular level is crucial for advancing research and therapeutic applications. ...
Professor Bertozzi opened up the field of bioorthogonal chemistry, allowing researchers to modify molecules in living systems by chemical methods without interfering with the original biochemical pathway. ...
Our goal in design is to find a set of promising variants that’s small enough to test in vitro/vivo (scale) while maximizing the fraction of capsids in this set which are viable (efficiency). ...
An additional challenge with the standard paradigm of studying only systemic PK outputs is the loss of insight into tissue-specific kinetics that can drive compound safety/tox dynamics10. ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. ...
The first one is an -galactosidase gene (melA), which facilitates the rapid identification of in vivo-induced genes. Second, the bacterial luciferase genes (luxAB) are transcriptionally coupled to the resolvase gene, which allows rapid validation and characterization of in vivo-induced genes. The system is implemented and validated in the ...