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Phenotyping Analysis Articles & Analysis

6 articles found

Preclinical Animal Models as A Resource to Explore Rare Diseases

Preclinical Animal Models as A Resource to Explore Rare Diseases

So far, some biotech giants have established a series of research and development technologies for genetically modified animal models, such as gene cloning, gene knockout plasmid construction, experimental animal embryonic stem cell manipulation, strain breeding, and phenotype analysis. Combined with these technologies, there would be more stable and reliable ...

ByProtheragen


How do you validate a pathway analysis method? How do you compare such methods?

How do you validate a pathway analysis method? How do you compare such methods?

My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? ...

ByAdvaita Bioinformatics


Research Highlight: Stanford University - Case Study

Research Highlight: Stanford University - Case Study

AdvaitaBio’s IPathwayGuide plays significant role in the research of a Stanford investigator. Stanford University is one of the world’s leading research and teaching institutions. With a 1.69 billion dollar annual sponsored research budget, Stanford has been delivering breakthrough discoveries in numerous domains. For over 6 years, Dr. Linda Yip has been conducting research at ...

ByAdvaita Bioinformatics


CD Genomics Perspective: NGS-Based Gene Panels for Cancer Research

CD Genomics Perspective: NGS-Based Gene Panels for Cancer Research

Gene panels make NGS and data analysis more economical, flexible and efficient. The use of them can improve the detection of genetically heterogeneous disorders and diseases with overlapping phenotypes, while assessing multiple potential genetic causes of suspicion. ...

ByCD Genomics


Rationale, Design, and Methodological Aspects of the BUDAPEST-GLOBAL Study (Burden of Atherosclerotic Plaques Study in Twins-Genetic Loci and the Burden of Atherosclerotic Lesions)

Rationale, Design, and Methodological Aspects of the BUDAPEST-GLOBAL Study (Burden of Atherosclerotic Plaques Study in Twins-Genetic Loci and the Burden of Atherosclerotic Lesions)

Abstract The heritability of coronary atherosclerotic plaque burden, coronary geometry, and phenotypes associated with increased cardiometabolic risk are largely unknown. ...

ByG3T Therapeutics


Unconventional genomic architecture in the budding yeast saccharomyces cerevisiae masks the nested antisense gene nag1

Unconventional genomic architecture in the budding yeast saccharomyces cerevisiae masks the nested antisense gene nag1

NAG1 encodes a 19-kDa protein, detected by Western blotting of hemagglutinin (HA)-tagged Nag1p with anti-HA antibodies and by β-galactosidase analysis of a NAG1-lacZ fusion. NAG1 is evolutionarily conserved as a unit with YGR031W in bacteria and fungi. Unlike the YGR031WP protein product, however, which localizes to the mitochondria, Nag1p localizes to the cell periphery, ...

ByAmerican Society for Microbiology (ASM)

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