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Neurodegenerative diseases | ELISA kits and antibodies for detection of pathological related markers for Alzheimer, Parkinson and ...
EAPII (also called TTRAP, TDP2) originally was identified as an interacting partner of oncogene ETS1, a founding member of ets transcription factor, and the cytoplasmic domain of CD40, a member of the tumor necrosis factor (TNF) receptor family. EAPII significantly represses ETS1 transcriptional activity and the synergistic transactivation by ETS1 and AP-1 or by ETS1 and NFκB. EAPII/TTRAP ...
The relative inaccessibility of human brain tissues has largely hampered the understanding of human neurological diseases and impeded drug development. ...