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Disease Mechanisms Articles & Analysis
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Infectious diseases are disorders caused by organisms — such as bacteria, viruses, or parasites. A vaccine is a specialized biological formulation that triggers the immune system to recognize and activate protective responses against specific disease-causing agents. With the global landscape of infectious diseases continually evolving, ...
Chronic Obstructive Pulmonary Disease (COPD) is a global health burden characterized by persistent airflow limitation and progressive lung damage. ...
This precise dissociation is pivotal for advancing studies on immune response and related disease mechanisms. Read the application note EPISODE 1: THE HEART EPISODE 2: THE LUNG EPISODE 3: THE LIVER ...
Obtaining viable single cells from lung tissue is essential for understanding respiratory function and disease mechanisms. Despite its importance, isolating these cells remains challenging. ...
This enhancement aims to offer more precise and comprehensive glycoprotein analysis, catering to the growing demands in the fields of biomedical research, disease biomarker discovery, and therapeutic development. Protein glycosylation, a major post-translational modification, significantly impacts protein folding, stability, and activity. Changes in glycoprotein abundance and ...
These models have been specifically designed to enable research on different types of diabetes including type 1, type 2, and gestational diabetes, providing valuable insights into disease mechanisms and potential treatment options. Diabetes mellitus is a chronic, systemic, metabolic disease caused by the long-term combination of genetic factors ...
Ace Therapeutics is a preclinical contract research provider engaged in metabolic disorders, infectious diseases and parasites, neurological disorders, ophthalmic diseases, gastrointestinal disorders, and immune system diseases. ...
Whether you are investigating the role of citrate synthase in disease mechanisms, optimizing biofuel production, or exploring the intricacies of mitochondrial function, this enzyme from Creative Enzymes is a powerful tool that can propel your research forward. ...
This comprehensive collection provides researchers with a unique resource to study various neurological conditions and accelerate their investigations into neurological diseases and disorders. CD Bioscience has been developing imaging technologies for many years and uses high content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging and other technologies ...
In the pursuit of advancing disease research and its treatment, animal cognitive behavior is studied in a wide range of animal species. ...
Depression is commonly seen in neurodegenerative and neurodevelopmental diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and autism spectrum disorders. Although the exact mechanisms are not fully understood, it is believed that anxiety and depression are caused by a combination of ...
This state-of-the-art technology enables scientists to pinpoint and characterize actively degrading RNA molecules, shedding new light on essential regulatory mechanisms. Key Highlights of CD Genomics' Degradome Sequencing Service: High-Precision Data: CD Genomics employs a cutting-edge sequencing platform that produces high-precision data with exceptional resolution. ...
Investigation of Complex Genomic Regions: LAA empowers scientists to delve into complex genomic regions that hold critical biological insights, such as regulatory elements, disease-related genes, and repetitive sequences. 3. Targeted Gene Analysis: Offering an economical and efficient solution for targeted gene analysis, LAA proves ideal for studying specific regions of ...
Gaining a deeper understanding of these intricate interactions is essential for deciphering disease mechanisms and identifying potential therapeutic targets. Far-Western Blot Analysis emerges as a powerful tool, allowing researchers to delve into the intricacies of protein networks, uncovering vital information about protein binding partners and unraveling the ...
The analysis of exosomal RNA content is crucial for unraveling their roles in health and disease. CD Genomics' Exosomal RNA Sequencing service utilizes state-of-the-art next-generation sequencing (NGS) technologies, enabling high-throughput and cost-effective analysis of exosomal RNA samples. ...
About HemoShear Therapeutics HemoShear Therapeutics, Inc. is a privately held clinical stage company developing treatments for rare diseases with significant unmet patient need. HemoShear’s drug discovery platform, REVEAL-Tx™, enables the Company’s scientists to create best-in-class, biologically relevant human disease models to uncover the ...
About HemoShear Therapeutics HemoShear Therapeutics, Inc. is a privately held clinical stage company developing treatments for rare diseases with significant unmet patient need. HemoShear’s drug discovery platform, REVEAL-Tx™, enables the Company’s scientists to create best-in-class, biologically relevant human disease models to uncover the ...
Despite affecting over 400 million people around the globe, rare diseases have largely been overlooked by traditional drug discovery methods. This is because traditional model often prioritise disease areas where there is a greater understanding of the basic underlying biology and which, in turn, generally come from the larger patient populations associated with more common diseases. This is part ...
CY6463 is an oral, first-in-class, central nervous system (CNS)-penetrant sGC stimulator that is being developed for neurological and neuropsychiatric diseases associated with cognitive impairment. CY6463 was designed to address multiple pathophysiological features of these disorders. ...
The Benevolent Platform™ is disease agnostic, meaning it can be applied to any disease, and is capable of generating novel targets at scale. Scientists and technologists from both companies will use the Benevolent Platform™ and biomedical Knowledge Graph — which uniquely includes AstraZeneca proprietary data with public and licensed data from ...