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Disease Mechanisms Services

9 services found

MedGenome - TCR Sequencing Service

MedGenome - TCR Sequencing Service

Manufactured by:MedGenome Inc.    based inCounty of New Castle, DELAWARE (USA)
TCR profiling holds great potential not only for understanding the mechanisms of development of the normal immune response, but also in providing insights into disease mechanisms and development of new therapeutics and treatment modalities in infectious diseases, autoimmunity and in immuno-oncology. However, identification of all ...
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Cecum Ligation and Puncture (CLP)-Induced Sepsis Model

Cecum Ligation and Puncture (CLP)-Induced Sepsis Model

Manufactured by:Creative Biolabs   based inShirley, NEW YORK (USA)
Rodent disease models are widely used for a broad range of project objectives, which involve investigation of pathological process and mechanism of disease, pre-clinical tests of potential therapeutic agents, ...
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Transformative Research Services

Transformative Research Services

by:Amgen Inc.   based inThousand Oaks, CALIFORNIA (USA)
Understanding the fundamental biological mechanisms of disease is a defining feature of Amgen's discovery research efforts—and a major contributor to the development of Amgen's deep and broad pipeline of potential new medicines. Amgen's "biology first" approach permits its scientists to first explore the complex molecular pathways of ...
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Creative Biogene - Multi-omics Analysis of Mitochondria

Creative Biogene - Multi-omics Analysis of Mitochondria

Manufactured by:Creative Biogene-Mitochondrial Research   based inNY, NEW YORK (USA)
To further meet the needs of multi-group joint analysis, through the integrated analysis of multi-group data, Creative Biogene provides a systematic and overall solution for global researchers, such as mitochondrial regulation mechanism, disease target screening, biomarker discovery, and so on. We provide new ideas for researchers studying mitochondrial molecular ...
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Disease Model Customized Service

Disease Model Customized Service

Manufactured by:Cloud-Clone Corp.   based inKaty, TEXAS (USA)
The development of human disease is very complex, to itself as experimental object to in-depth study of the mechanism of disease, the accumulation of clinical experience not only in time and space are limited and many experiments on the moral are restricted. Animal models can provides the basic platform for the study of safety research of drugs, ...
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Drug Development Partnerships Services

Drug Development Partnerships Services

Manufactured by:Mimetas B.V.   based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
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MtoZ Biolabs - Olink Analysis Service

MtoZ Biolabs - Olink Analysis Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
With the increasing focus on personalized healthcare, there is a growing demand for biomarkers for early diagnosis, prognosis, patient stratification, or monitoring treatment response. Compared with genetic biomarkers, protein biomarkers provide higher degrees of differential information. Olink proteomics is based on a unique proximity extension assay (PEA) technique that enables simultaneous ...
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MtoZ Biolabs - mRNA 3’ poly(A) Tail Analysis Service

MtoZ Biolabs - mRNA 3’ poly(A) Tail Analysis Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
In eukaryotic cells, the 3' end of mRNA is often extended with a poly(A) tail, a sequence of purine nucleotides. The poly(A) tail is a long chain of adenosine nucleotides of variable length. This tail is crucial for mRNA stability, transport, and translation. The analysis of mRNA's 3' poly(A) tail is a vital technique in studying the polyadenylation at mRNA molecules' 3’ ends, with significant ...
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Enginered Tissue-Based High Content Analysis - Drug Discovery Services

Enginered Tissue-Based High Content Analysis - Drug Discovery Services

Manufactured by:InvivoSciences, Inc. (IVS)   based inMadison, WISCONSIN (USA)
Human engineered tissue (EHT)-based high content analysis can be applied to drug discovery projects at their compound screening and lead optimization stage. Mass-produced human engineered tissues will recapitulate physiological functions of native tissues in micro tissues growing in 96-well plates or 384-well plates (coming soon). Patient-derived cells can also be used to fabricate engineered ...
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