Metabolic Pathway Articles & Analysis
25 news found
Creative Proteomics, a leader in proteomics and metabolomics services, has officially launched its innovative Central Carbon Metabolism (CCM) Analysis Service, designed to transform the study of cellular energy dynamics and metabolic pathways in both health and disease. ...
By enhancing insulin production, Semaglutide enables exploration into methods of regulating blood sugar levels, making it a focal point for researchers investigating metabolic regulation. Its approval nod from the FDA Advisory Committee further underscores its potential, with Semaglutide holding a considerable molecular weight of 4114 and a complex formula of C187H291N45O59. ...
In metagenomics, where researchers deal with a multitude of libraries derived from diverse microbial populations, even minor errors can skew the analysis of protein functions and metabolic pathways associated with specific genes. Therefore, implementing a rigorous quality control (QC) protocol is essential to ensure the reliability of the data. ...
Focus on Pharmacokinetics and Toxicology Understanding a drug's absorption, distribution, metabolism, and excretion (ADME) in animal bodies is crucial for determining appropriate dosages and minimizing adverse effects. CD Formulation's pharmacokinetic services provide detailed analyses of these processes, catering to the distinct metabolic ...
By generating high-quality, contiguous sequences, researchers can uncover the intricate details of fungal genomes, including the identification of novel genes, the elucidation of metabolic pathways, and the exploration of evolutionary relationships. ...
This cutting-edge enzyme is poised to revolutionize research in cellular metabolism, bioenergetics, and a wide range of life science applications. ...
To help scientists better understand the regulation and role of mTOR in metabolic regulation and to address some of the major unanswered questions, CD BioSciences has developed a series of research solutions, empowering researchers to delve into the intricate world of metabolic signaling pathways. ...
CD BioGlyco, a biotechnology company that provides multi-omics analysis of cancer cell glycolysis including genomics, proteomics, metabolomics and metabolic fluxomics, now offers analysis of glycolytic enzymes in cancer cells, enabling thorough understanding of cancer cell glycolysis pathways. ...
Bacterial/fungal/viral/parasitic resistance studies: the metabolic state of bacteria is associated with a range of genetic and phenotypic resistance mechanisms. Thus, metabolomics is used to determine the relationship between antimicrobial resistance (AMR) mechanisms and microbial metabolism. 2. Tumor drug resistance studies: tumor cells develop drug resistance ...
As one of the most common molecules in cells, proteins are of great significance for regulating various metabolic pathways and numerous biological processes in cells. In general, proteins do not function individually, but through interactions with each other, known as protein-protein interactions (PPIs), to accomplish their corresponding tasks. ...
"Compounds labeled with stable isotopes maintain physicochemical properties, allowing consistent interactions within biochemical pathways. This method applies to many molecules as well as carbohydrates," the chief technician of BOC Sciences explained, "isotope-labeled carbohydrates can trace the entire molecule or specific atom to reveal quantitative and qualitative analysis of ...
These new signaling pathways and previously launched metabolic signaling pathways, such as insulin signaling pathway and mTOR pathway, will help support scientists in all aspects of cell death study. 5' AMP-activated protein kinase, or AMPK, plays a central role in cellular energy homeostasis. ...
These data and data published previously in the New England Journal of Medicine suggest that a two-pronged approach for the treatment of rCDI, with standard-of-care antibiotics to kill vegetative C. difficile bacteria followed by investigational agent SER-109 to repair the disrupted microbiome through engraftment of Firmicutes bacteria and the modulation of multiple metabolic ...
For example, bacterial expression profiling has identified major changes in the expression of metabolic pathways relevant to disease pathogenesis in the human microbiome. ...
Tarka worked at GlaxoSmithKline in the Metabolic Pathways and Cardiovascular Therapeutic Area. She has been on the faculty and had numerous major teaching and clinical responsibilities at the University of Pennsylvania and affiliated hospitals. ...
Targeted proteomics can be applied to system-level studies of post-translational modification, protein conformation, protein-protein interaction, kinetics, and metabolic and signal transduction pathways. Targeted proteomics quantitative technology mainly includes MRM (multiple reaction monitoring) and PRM (parallel reaction monitoring). ...
By using stable isotope (such as 2H, 13C and 15N) labels, MFA can identify and quantitatively evaluate the metabolic effects of metabolic pathways by observing the position of the isotope labels along the metabolic pathway. ...
Metabolomics is the study of metabolite changes in organisms, which can provide information on the metabolism of microorganisms in the gut. By detecting metabolites in various body fluids (e.g., urine, plasma, and feces), functional profiles of common metabolites of gut microbes and hosts can be obtained, which can help to study metabolic ...
Adjacent cells or distant cells bind to recipient cells through exosomes, releasing biologically active molecules such as lipids, proteins, and nucleic acids, which can exchange genetic or metabolic information. Lipids not only play an important role in the structure of exosomal membranes, but also play an important role in the formation and release of exosomes into the ...
(Fractyl), a life sciences company dedicated to novel therapeutic interventions that can reverse the metabolic disease epidemic, today announced a first close of $55 million in a Series E financing. ...