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Genetic Mutation Equipment & Supplies
12 equipment items found
Manufactured by:TIB Molbiol Syntheselabor GmbH based inBerlin, GERMANY
In 2005 we developed our first LightMix Kit detecting bird flu Influenza A H5N1. Since then, we have created many kits testing for different pathogens, hematology markers, genetic mutations and polymorphisms. ...
Manufactured by:Genetic Signatures Ltd. based inNewtown, AUSTRALIA
A full list of the essential respiratory pathogen targets is listed in the table below. User friendly medium to high-throughput systems are available that support Genetic Signatures’ full range of unique 3base™ assays for detecting infectious disease. This patented 3base™ technology has many advantages over conventional 4-base assays, including improved sequence ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
CRISPR/Cas9 genome editing can make permanent, precisely targeted changes in patients’ chromosomes and repair the underlying genetic mutation, whereas more traditional gene therapy typically involves introducing a non-permanent copy of a gene into patients’ cells. These attributes of CRISPR/Cas9 provide a significant therapeutic edge over other gene ...
Manufactured by:KORU Medical Systems based inMahwah, NEW JERSEY (USA)
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic, life-threatening blood disorder characterized by the complement-mediated destruction (hemolysis) of oxygen-carrying red blood cells. The disease is caused by a genetic mutation in the DNA and causes red blood cells to be missing a critical protein responsible for protecting them. Hemolysis occurs in ...
by:Gain Therapeutics, Inc. based inBethesda, MARYLAND (USA)
Protein misfolding is the root of many diseases, including lysosomal storage disorders and neurodegenerative ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
OncoPeptTUME — A novel in-silico approach to model the tumor microenvironment and predict treatment efficacy and long-term survival benefits for immunotherapy applications. Cancer immunotherapy is now established as a major therapeutic modality. Cancer immunotherapy drugs elicit their anti-tumor immune response in a subset of the treated patients by activating CD8 T-cells and provide ...
Manufactured by:Advanced Molecular Diagnostics based inNottingham, UNITED KINGDOM
More than 1,000 mutations in the CFTR gene have been associated with cystic fibrosis. Most of these mutations in the CFTR gene change the production, structure, or stability of the chloride channel. All of these charevent the channel from functioning properly, which impairs the transport of chloride ions and the movement of water into and out of cells, resulting in cells lining the passageways of ...
by:Tesis Biosciences based inScottsdale, ARIZONA (USA)
CGx Testing is a preventative gene test that looks for specific inherited changes (mutations) in a person’s genetic make-up. Harmful mutations may increase a persons’ chance, or risk, of developing a disease such as cancer. These conditions are considered hereditary. Appropriate genetic testing may be used to ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:EGFR，KRAS，BRAF，PIK3CA，NRAS，HER2，MET，AKT1，KIT，PDGFRA，ALK，ROS1，RET（Detetion of 13 genes） Detection Significance:Guiding the selection of targeted drugs for lung cancer ...
Manufactured by:Therawis based inMunich, GERMANY
Exosomes (30-150 nm) are the smallest type of extracellular microvesicles (EMV), produced through inward budding multivesicular bodies (MVB), resulting in intra-luminal vesicles (ILV). ILVs are released into the extracellular media by exocytosis. Exosome-associated proteins are used to isolated microvesicles from biological fluids such as blood, urine or cerebral fluid and to identify the source ...
Manufactured by:Scopus BioPharma based inNew York, NEW YORK (USA)
Our licensed gene therapy, CO-sTiRNA™, is a dual-action STAT3 inhibitor. STAT3 is a gene that drives tumor cell growth and anti-tumor immune suppression. CO-sTiRNA™ is a highly selective and targeted gene therapy that silences the activity of the STAT3 gene by way of RNA interference. CO-sTiRNA™ also stimulates TLR9 receptors to activate the body’s immune defense to ...
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
Our lymph node-targeted mKRAS cancer vaccine; Our Amphiphile (AMP)-powered lead candidate, ELI-002, generates a robust immune response against mutant Kristen rat sarcoma (mKRAS), with the potential to offer patients a stronger fight against the most aggressive cancers. Preliminary data have shown that ELI-002 produces a potent mKRAS-specific T-cell response, including both CD4+ and CD8+ ...