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In Vitro Model Equipment Supplied In Usa
41 equipment items found
Manufactured by:Cayman Chemical based inAnn Arbor, MICHIGAN (USA)
It also prevents glucose-oxygen deprivation-induced increases in reactive oxygen species (ROS) and lactate dehydrogenase (LDH) release in primary rat cortical neurons in an in vitro model of ischemia when used at a concentration of 10 µM.3 SP-8356 (5 µM) inhibits the migration and invasion of MDA-MB-231 breast cancer ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
We develop 3D InSight™ Microtissues using the most advanced 3D cell culture technologies available to produce highly predictive, fully QC’d organotypic in vitro models ready to use in pharma drug discovery, efficacy and safety. These microtissues form the foundation of our 3D InSight™ platforms for drug discovery and safety, which we rely on in ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. The quad-culture Emulate Liver-Chip combines four human cell types in a dynamic microenvironment to support in vivo like gene expression, ...
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
The Scissor N3 is an advanced in vitro model designed to simulate the subcutaneous injection of biopharmaceuticals. This device is particularly useful during the formulation development phase, enabling researchers to perform rank ordering of formulations and excipient screening. It allows for a thorough understanding of how a drug behaves post subcutaneous ...
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
Combining class I and class II engineering to create Universal Donor Cells (UDCs) that are appropriate for developing numerous differentiated cell ...
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Automated sorting and isolation of single spheroids and organoids. A game-changer in drug screening and other applications where standard 3D models will gradually replace traditional animal models. spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling. Using precision dispensing technology together with advanced image-based sorting ...
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
T4, a mouse mammary gland tumor cell line, has been widely used in cancer research and drug development in vitro and in vivo. 4T1/firefly luciferase (CMV) stable cells express transgenically firefly luciferase under the control of the CMV promoter. The proliferation and trafficing of the cells could be monitored in Bioluminescence imaging in small animal xenograft ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
A standardized in vitro rat islet model for translational diabetes studies and toxicity testing. InSphero 3D InSight™ Rat Islet Microtissues are currently in the final stages of product development and quality control testing. If you are interested in beta testing this product to help us further characterize the model and develop useful ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Custom 3D InSight™ Animal Liver Microtissues are available only on request for research partners, who perform translational toxicology studies on a regular basis. We offer fully tested and highly standardized monkey, dog, and rat liver toxicology models produced using species-specific primary hepatocytes and non-parenchymal liver cells. Ideal for studying species-specific ...
Manufactured by:Regenerative Medical Solutions Inc. (RMS) based inMadison, WISCONSIN (USA)
ILC Cells kit contains islet like cells and supplement media. This product has been specially formulated to contain cryopreserved single cells that are frozen in vials. The islet like cells in this kit are derived from human iPSC and closely resemble human cadaveric islets from a morphological and functional ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking to add functionality to your existing microscopy setup? The BioFlux 200 expands on BioFlux One by enabling up to 24 temperature-controlled flow cell assays in parallel. The dual flow control capability enables more complicated 2-phase flow assays. It is also compatible with the BioFlux Quattro for up to 96 parallel flow ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking for a simple microfluidic solution for your current microscope? The BioFlux One can run up to 24 simultaneous flow cell experiments and is ideal for platelet aggregation, leukocyte adhesion, and biofilm analysis. It works with your existing inverted microscope and is compatible with fluorescence, brightfield, phase and confocal ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Fail early, fail fast! Assess Risk of Liver Injury Due to Compound Exposure with 3D InSight. 3D InSight Human Liver Microtissues are pharma-validated, preclinical co-culture liver models for toxicology testing that have been shown to achieve 2X higher sensitivity for DILI prediction compared to traditional 2D PHH. These advanced 3D liver models, which combine multi-donor diversity with ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ATP-adenosine pathway. The anti-CD39 ...
Manufactured by:Fluxion Biosciences Inc based inAlameda, CALIFORNIA (USA)
Looking for a simple, fully integrated solution? The BioFlux DCIS integrates the BioFlux controller with a digital microscope, fluorescence, and two cameras. The easy-to-use live cell imaging system been designed with advanced capabilities to simplify demanding cell-based imaging applications with convenience and ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis to liver inflammation and ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
An in vitro PDX model with in vivo-like heterogeneity. 3D InSight™ Tumor Microtissues from Patient-Derived Xenografts (PDX) are custom assay-ready 3D in vitro tumor models engineered to reflect complex tumor biology without the use of artificial matrices. Ideal for early stage cancer drug efficacy testing and screening ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Research mechanisms of neuroinflammation and evaluate the effect of therapeutics in a comprehensive model of the neurovascular ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 ...