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In Vivo Human Equipment & Supplies
27 equipment items found
by:Alloy Therapeutics, Inc. based inLexington, MASSACHUSETTS (USA)
ATX-Gx™, our first platform, is a royalty-free suite of immunocompetent transgenic mice enabling best-in-class in vivo human antibody discovery. There are three ways to access the ATX-Gx™ ...
Manufactured by:Episkin based inLyon Cedex 7, FRANCE
EpiSkin is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on a collagen matrix at the air-liquid interface. This model exists at different stages of maturity. This model is histologically similar to the in vivo human ...
Manufactured by:Episkin based inLyon Cedex 7, FRANCE
SkinEthic RHE is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. This model exists at different stages of maturity. This model is histologically similar to in vivo human ...
Manufactured by:Episkin based inLyon Cedex 7, FRANCE
SkinEthicTM RHEACF is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. Improved production so every single process is guaranteed devoid of any animal constituents and tissue production now guaranteed devoid of any animal components with ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GSK2983559 free acid (compound 3) is an orally active and potent receptor interacting protein 2 (RIP2) kinase inhibitor. GSK2983559 free acid can block many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant ...
Manufactured by:Futura Medical based inGuildford, UNITED KINGDOM
Scientific advisory meeting held with MHRA confirming the need of a Phase 3 study to support the improved skin permeation including potential superior efficacy claims. Exploring the feasibility of a clinical study to satisfy the Phase 3 requirements for both UK and US approval. Development currently on ...
Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA
Fully humanized anti-human 4-1BB monoclonal antibody. Agonistic effect of EU101 promotes cytotoxic T lymphocyte response and it leads to eradication of ...
Manufactured by:Eutilex Co.,Ltd. based inSeoul, SOUTH KOREA
Fully humanized therapeutic monoclonal antibody. This could convert type II macrophage to Type I. Anti-tumor efficacy of the antibody can be achieved by modulating tumor ...
by:Zucara Therapeutics Inc. based inToronto, ONTARIO (CANADA)
Zucara Therapeutics is developing ZT-01, a first-in-class, once-daily therapeutic to prevent insulin-induced hypoglycemia in patients using insulin therapy. ZT-01 is designed to inhibit somatostatin, a pancreatic hormone that impairs the glucagon response to hypoglycemia in people with insulin dependent diabetes. ZT-01 restores glucagon secretion to prevent hypoglycemia, which could dramatically ...
Manufactured by:3D Bioprinting Solutions based inMoscow, RUSSIA
FABION is the first Russian-made 3D bioprinter of original design and make for printing live and functional tissue and/or organ constructs, allowing precise layer-by-layer deployment of tissue spheroids (bioink) in hydrogel (biopaper) according to a programmed digital model. Thanks to the unique design and engineering solutions developed by the 3D Bioprinting Solutions Laboratory, FABION is a ...
Manufactured by:NuLiv Science based inBrea, CALIFORNIA (USA)
InnoSlim® is a pharmaceutical-grade glucose and lipid metabolic regulator through activation of the adiponectin and AMPK signaling ...
Manufactured by:Angany Inc. based inSt-Jean, QUEBEC (CANADA)
We aim to provide safe, dependable and lasting relief from allergy. We have developed a unique therapeutic approach based on a proprietary allergy vaccine technology to address the specific challenge of allergy (eBioparticle-Potentiated ...
Manufactured by:Acuitas Therapeutics based inVancouver, BRITISH COLUMBIA (CANADA)
Acuitas specializes in the development of lipid nanoparticle delivery systems for molecular therapeutics. Our scientists have synthesized over 500 novel cationic lipids which have been evaluated in in vivo models including non-human primate (NHP) models. This evaluation characterizes the potency and safety of these LNP carriers for delivery of nucleic acid ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
UNBS5162 is a pan-antagonist of CXCL chemokine expression, with anti-tumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Meisoindigo (Dian III), a derivative of Indirubin (HY-N0117), halts the cell cycle at the G0/G1 phase and induces apoptosis in primary acute myeloid leukemia (AML) cells. Meisoindigo exhibits high antitumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM). Degarelix acetate (FE 200486) is used for the research of prostate ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate ...
Manufactured by:Genenta Science based inMilano, ITALY
After apheresis collection, a functional copy of the therapeutic gene is inserted into the patient’s own HSPCs using a non-replicating lentiviral vector. This is an ex-vivo process called transduction. We believe that LVVs are the first choice for ex-vivo gene therapy in humans because they can efficiently transduce HSPCs with potentially ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
W-7 hydrochloride is a selective calmodulin antagonist. W-7 hydrochloride inhibits the Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 μM and 51 μM, respectively[1][2]. W-7 hydrochloride induces apoptosis and has antitumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Isoacteoside is a natural product that can significantly inhibit the formation of glycation end products. Isoacteoside regulates the AKT/PI3K/m-TOR/NF-κB signaling pathway, induces apoptosis in OVCAR-3 cell. Isoacteoside exhibits antitumor, anti-inflammatory, anti-obesity and neuroprotective ...