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Retinal Cell Equipment & Supplies
35 equipment items found
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
Ocugen’s modifier gene therapy platform is a cutting-edge technology licensed from the Schepens Eye Research Institute of Massachusetts Eye and Ear (Harvard Medical School) and involves targeted delivery and expression of one or more nuclear hormone receptor genes (NHRs) in the disease tissues. NHRs play a vital role in regulating retinal cell development, ...
Manufactured by:Ikarovec based inNorwich, UNITED KINGDOM
Age-related macular degeneration (AMD) is a painless eye condition that leads to the gradual loss of central vision and is the most common cause of sight loss in the developed world and the third most common globally. Around 600,000 people in the UK currently have sight loss caused by AMD and around 70,000 new cases are diagnosed every year. Macular degeneration develops when the macula (the part ...
Manufactured by:Diopsys, Inc. based in, NEW JERSEY (USA)
Diopsys® PERG (pattern electroretinography) vision tests provide you with objective, functional information on the performance of retinal ganglion cells. These test results help you identify “stressed” cells at a subclinical stage, when the cells have become dysfunctional but are still alive.1 By starting ...
Manufactured by:Konan Medical USA, Inc. based inIrvine, CALIFORNIA (USA)
Visual electrophysiology is an objective, non-invasive method of assessing function in various mechanisms of the entire visual pathway. Designed for a broad range of visual function assessments, EvokeDx uses conventional as well as novel, proprietary stimuli to illicit responses from discrete sub-divisions of neural visual pathways. ...
Manufactured by:The Electrospinning Company Ltd. based inDidcot, UNITED KINGDOM
Culture of retinal pigment epithelium cells on the Mimetix scaffold. The aim of this case study was to evaluate whether the Mimetix scaffold can mimic Bruch’s membrane and assess the attachment, proliferation and differentiation of human RPE cells (ARPE-19) cells within it as a treatment option for age-related macular ...
Manufactured by:Topcon Europe Medical BV based inCapelle aan den IJssel, NETHERLANDS
Introducing automated OCT, true color fundus photography and automated OCT Angiography in one compact instrument. With the touch of a button, OCTA provides you instantaneous vascular structure information – from our world-renowned, multi-modal OCT ...
Manufactured by:Lineage Cell Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
On December 20, 2021, Lineage announced that it has entered into an exclusive worldwide collaboration and license agreement with Roche and Genentech, a member of the Roche Group, for the development and commercialization of OpRegen for the treatment of ocular disorders, including advanced dry age-related macular degeneration (dry AMD) with geographic atrophy (GA) in a transaction worth up to $670 ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
A functional monolayer in vitro model of retinal pigment epithelial cells generated from human iPSCs for accurate prediction of clinical outcomes. The retinal pigment epithelial (RPE) cell model is composed of a monolayer of RPE cells cultured in 24-well Transwell® plates. RPE characterisation includes: ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Light responsive retinal organoids for accurate prediction of clinical outcomes. The retinal organoids recapitulate the complex structure of the human retina with laminar cell organisation mimicking embryonic development. They contain the outer photoreceptor segment of the retina that responds to light. Available analytical readouts: ...
Manufactured by:Lutronic Vision based inBillerica, MASSACHUSETTS (USA)
R:GEN is the only retinal laser proven to deliver safe, efficacious and precise targeting of Retinal Pigment Epithelium (RPE) cells. R:GEN’s proprietary Real-Time Feedback, Dual Dosimetry, and Auto Ramp-up technologies ensure precise targeting of RPE cells without damage to ...
by:PIXIUM VISION based inParis, FRANCE
The Prima System is intended to partially replace the normal physiological function of the eye’s photoreceptor cells by electrically stimulating the nerve cells of the inner retina, which then transmit the visual information to the brain via the optic ...
Manufactured by:Diopsys, Inc. based in, NEW JERSEY (USA)
The Diopsys® ffERG (full field electroretinography) module includes several important protocols to help you detect disease early and manage patient care. Understanding how your patient is responding to treatment is important. Is their visual function improving? Is their disease progressing? Diopsys® ffERG / Flicker vision tests provide objective, functional information about global ...
Manufactured by:HEALIOS K.K. based inTokyo, JAPAN
The retina is a light-sensitive nerve layer (similar in function to the film in a camera), lining the inner surface of the human eye. In the retina, light signals are converted to electrical signals and transmitted to the brain via the optic nerve. Eventually, light signals are processed as vision in the visual cortex. In the center of the posterior pole of the human retina, there is a special ...
Manufactured by:NeuroScientific Biopharmaceuticals Ltd. based inCottesloe, AUSTRALIA
EmtinB is the lead candidate that has shown to closely mimic the neuroprotective and neuroregenerative ability of MT-II. ...
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
OCU400 (AAV-NR2E3) is a novel gene therapy product candidate with the potential to be broadly effective in restoring retinal integrity and function across a range of genetically diverse inherited retinal diseases (“IRDs”). It consists of a functional copy of a nuclear hormone receptor (“NHR”) gene, NR2E3, delivered to target ...
Manufactured by:HEALIOS K.K. based inTokyo, JAPAN
Induced pluripotent stem cells (iPSCs) are established by introducing several factors to somatic cells such as skin cells. iPSCs can differentiate into the cells of a various tissues or organs (pluripotency) and grow indefinitely (proliferation). The objective of iPSC regenerative medicine is to restore cellular function by replacing dysfunctional tissues with cell therapy medicines, which are ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is a potent, selective and orally active PKC inhibitor with IC50s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCε, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
BML-280 (VU0285655-1) is a potent and selective phospholipase D2 (PLD2) inhibitor. BML-280 has the ability to prevent caspase-3 cleavage and reduction in cell viability induced by high glucose. BML-280 can be used for rheumatoid arthritis ...