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Tumor Mutation Equipment & Supplies
40 equipment items found
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ...
Manufactured by:Tempus based inChicago, ILLINOIS (USA)
648 gene panel + Whole transcriptome RNA sequencing with validated fusion detection, Enriched for clinically relevant genes and genes of emerging clinical relevance, Immunotherapy Metrics: MSI Status, Tumor Mutational Burden (TMB), IHC Options: Mismatch Repair (MMR), PD-L1 (22C3, SP142, and 28-8 clones), Available Add-on Tests: Tumor Origin (TO), ...
by:Evaxion Biotech A/S based inHørsholm, DENMARK
PIONEER is our proprietary AI platform for the rapid discovery and design of patient-specific neoepitopes used to derive immuno-oncology therapies. It has been shown that neoepitopes, which arise from patient-specific tumor mutations, play a critical role in T-cell mediated antitumor immune ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:BCR-ABL gene T315I mutation detection. Detection Significance:Detect the resistance mechanism of conventional targeted drugs in patients with chronic myeloid ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
FocuSCOPE is a high-throughput single cell multi-omics sequencing solution that can detect both genetic variants and transcriptome from the same single cells. Thus, FocuSCOPE® provided a tool to decipher the connection between genotype and phenotype at single cell ...
by:Castle Biosciences, Inc. based inFriendswood, TEXAS (USA)
Our DecisionDx-UMSeq is a 7-gene test that uses next-generation sequencing (NGS) to identify somatic mutations relevant to uveal melanoma. Researchers believe that identifying mutations in tumor genes may someday help guide treatment decisions. Because the amount of tumor biopsy tissue is limited, it is important to gain as much ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:RET gene (12 fusion mutations). Detection Significance:Guiding the selection of RET inhibitor ;Reclassification of follicular ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:7 MGMT promoter region methylated loci. Detection Significance:Predicting the therapeutic effect of Temozolomide;Auxiliary prognosis of patients with ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:MLH1 methylated loci. Detection Significance:Presence of MLH1 hypermethylation is consistent with sporadic ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Adaptate Biotherapeutics is focussed on therapeutic antibodies which harness the potential of patients’ own gamma delta T cells in situ. Gamma delta T cells play a critical role in immune surveillance, recognising malignant/transformed cells through a pattern of stress markers and exerting potent and selective cytotoxicity. The recognition mechanism is not MHC restricted and not ...
Manufactured by:EntroGen, Inc. based inWoodland Hills, CALIFORNIA (USA)
The KRAS gene encodes a small GTPase that plays a key role in transducing signals from the epidermal growth factor receptor (EGFR) to downstream effectors. KRAS mutations have been commonly found in several types of human malignancies, such as metastatic colorectal cancer (mCRC), lung adenocarcinoma and thyroid cancer. The most common mutations are found in ...
Manufactured by:Tempus based inChicago, ILLINOIS (USA)
Tempus xE (version 2) is a whole exome next-generation sequencing assay that analyzes the entire coding region (exome) of the patient’s genome, combined with whole transcriptome RNA sequencing. Clinical sequencing is performed to 500x depth of coverage for tumor specimens and 150x for normal specimens for the clinically enhanced regions (648 genes). Non-enhanced regions are performed at ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:BRCA1, BRCA2 whole exome sequencing and Includes ±20 bp regions at exon-intron junctions. Detection Significance:Predicting prognosis ;Auxiliary diagnosis;Guiding the selection of ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
OncoPeptTUME — A novel in-silico approach to model the tumor microenvironment and predict treatment efficacy and long-term survival benefits for immunotherapy applications. Cancer immunotherapy is now established as a major therapeutic modality. Cancer immunotherapy drugs elicit their anti-tumor immune response in a subset of the treated patients by activating CD8 T-cells and provide ...
Manufactured by:Sysmex Partec GmbH based inGoerlitz, GERMANY
Highly sensitive down to 0.06 % MAF, Able to detect 6 MM with 95 % confidence across all mutations (absolute quantification), High flexibility of between 2-16 samples/run, Fast TAT (2 days), Convenient software. Plasma-SeqSensei (PSS) BC RUO Kit allows for the highly sensitive and specific detection of mutations in circulating tumour DNA (ctDNA) from the plasma of patients with breast cancer. The ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:K-ras (covering 21 loci related to targeted drugs). Detection Significance:Guiding the selection of KRAS G12C inhibitor , anti-EGFR and ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:EGFR (covering exons 18, 19, 20 and 21, total 30 loci related to targeted drugs). Detection Significance:Guide the selection of ...
Manufactured by:Elicio Therapeutics based inBoston, MASSACHUSETTS (USA)
ELI-008 is a multivalent lymph node–targeted AMP peptide vaccine developed to target p53 hotspot mutations. p53 is a tumor-suppressing protein that controls the cell cycle, DNA replication, and uncontrolled cell division during tumor growth.4 Mutations in the p53 protein lead to uncontrolled ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:B-raf（V600）(7 mutations). Detection Significance:Guiding the selection of BRAF/MEK inhibitor , anti-EGFR and anti-HER2 ; Auxiliary ...
Manufactured by:BridgeBio Pharma, Inc. based inPalo Alto, CALIFORNIA (USA)
SHP2, encoded by the PTPN11 gene, links growth factor signaling with the downstream RAS/ERK/MAPK pathway to regulate cell growth and division. Over-activity of this pathway, often driven by distinct gene mutations, causes or contributes to many human cancers. Inhibiting SHP2 offers a new approach to treat tumors relying on this pathway. SHP2 also suppresses ...