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Creative Bioarray Rss Services In North America
58 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
As compounds move from discovery to development, the need for even more detailed and precise metabolite data becomes increasingly important, both to understand the characteristics of the candidate drug in humans and to fulfill the regulatory requirements that will underpin a successful drug registration. Creative Bioarray has deep expertise in the profiling, identification and structural ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications for the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications for the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Microglia, one of the glial cell types in the CNS, is an important integral component of neuro-glial cell network. They have been observed in the brain parenchyma from the early stage of development to the mature state. Human Microglia (HM) act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vivo studies are done toward the end of the lead optimization process on selected candidates for final characterization and selection. GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both side-effect profiling and efficacy according to your requirement. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Kupffer cells are resident liver macrophages and play a critical role in maintaining liver function. Under physiological conditions, they are the first innate immune cells that protect the liver from bacterial infection. Under pathological conditions, they are activated by different components and can differentiate into M1-like (classical) or M2-like (alternative) macrophages. The metabolism of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
EBs are three-dimensional aggregation of three germ layer cells. The formation of Embryoid Body is a routine method for the differentiation of hiPSCs into different cell lineages. One of the major advantages of this method is that it is performed in vitro with standard tissue culture approaches and materials, thereby avoiding the regulatory problems and substantial costs associated with ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Migration is a key property of live cells and critical for normal development, immune response, and disease processes such as cancer metastasis and inflammation. Methods to examine cell migration are very useful and important for a wide range of biomedical research such as cancer biology, immunology, vascular biology, cell biology and developmental biology. With comprehensive list of cell lines ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human CD34+ Progenitor Cells, a transmembrane glycoprotein expressed on the surface of hematopoietic progenitor cells and small vascular endothelial cells, is considered to be a marker of hematopoietic stem cells and hematopoietic progenitor cells. CD34+ cells have been shown to possess colony-forming potential in short-term assays, maintain long-term colony-forming potential in in vitro culture, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The SUP-T1 established from the pleural effusion of an 8-year-old boy with T-lymphoblastic lymphoma in relapse. These cells are E-rosette, Leu 5, OKT9 and CALLA negative. They also express β2M, Leu 1, 2, 3a, 4, 6, 9 and OKT10 antigens and are CD4 positive. These cells are negative for Tac, HLA-DR and surface immunoglobulin. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray's tumor cell panels are based on key component of cell signaling pathways or by cancer genes. Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Tissue microarray (TMA) refers to the relocation of multiple tissues blocks to observe multiple samples on the same slide. TMA contains biomolecules such as proteins, lipids, carbohydrates, DNA or RNA in their preserved state, providing a high-throughput platform for quick analysis of molecular markers associated with disease diagnosis, prognosis or physiological status. Our in-house ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Diabetic Type I and Type II Human Skeletal Muscle Myoblasts (HSMM) are isolated from donors diagnosed with either Diabetes Type I or Diabetes Type II. Additional donor information is available by contacting Scientific Support. Diseased cells are tested in the same SkGM™-2 Skeletal Muscle Growth Media as the normal cells allowing for easy comparisons between diseased and normal tissue. Both are ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has developed human highly immortalized differentiated cell lines from various human tissues that show stable growth characteristics and phenotypes and have a high potential for production of complex biopharmaceuticals such as recombinant proteins, vaccines or extracellular vesicles. Creative Bioarray provides already established cell lines to get proof-of-principle for new ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
As sentinels of the immune system, Normal Human Dendritic Cells (DCs) are located in all tissues, especially those at the interface between the external environment and the body, such as lung, intestine, and skin. DCs are divided into plasmacytoid DCs (pDCs) and conventional DCs (cDCs), cDCs are further split into type 1 (cDC1) and type 2 (cDC2). Functionally, cDCs include two states: immature ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human cord leukocyte cell line established by co-cultivation with human ATL cells. Tumor Cells MT-2Org ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cat.No. CSC-C9100W Description The Farage cell line was adapted to culture in 1990 from a lymph node biopsy of a patient with diffuse large cell non-Hodgkin's lymphoma (DLCL). Species Human Source lymph ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
With a few exceptions, the immune system of humans and experimental animals are very similar. Most drugs that inhibit the immune system in humans produce similar results in rodents, and the mechanisms for immunosuppressive action are similar. Creative Bioarray has validated and implemented a series of standardized immunotoxicity testing protocols based on experimental animal models, which are ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The different regulations of cosmetics and the increase in consumer awareness have prompted researchers to investigate the effects of the chemicals content and the active ingredients on human health in more depth. Creative Bioarray is an industry leader in bioanalysis services for the cosmetics industry. More than half of our scientific staff have Doctor/Master degrees and boast 10+ years of ...