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Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Dexmedetomidine hydrochloride is a white or almost white powder that is freely soluble in water and has a pKa of 7.1. Dexmedetomidine hydrochloride is a potent α2-adrenoceptor agonist, which produces and analgesia, about 8 times higher selective affinity for the α2/α1-adrenoceptor than clonidine. Alfa Chemistry offers high quality of dexmedetomidine hydrochloride which meets the CP & EP ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Hydrocortisone butyrate is a synthetic glucocorticoid. Binding and activation of the glucocorticoid result in the activation of lipocortin that inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, a precursor for inflammatory mediators prostaglandins and leukotrienes, thereby inhibiting inflammation. In addition, glucocorticoid also stimulates ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
PF-06821497 is a potent EZH2 Inhibitor which can be used for the treatment of relapsed/refractory SCLC (small cell lung cancer), castration resistant prostate cancer, and follicular lymphoma. Alfa Chemistry offers high quality of PF-06821497 which can be a potent EZH2 Inhibitor for the treatment of relapsed/refractory SCLC (small cell lung cancer), castration resistant prostate cancer, and ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Nitrocellulose (NC) membranes are a series of paper-like matrices with micro-scale porous structures. Due to their good biocompatibility, unique physical and chemical properties, and the ability to immobilize various biomolecules, NC membranes have been widely used in the biomedical field. For example, NC membranes are commonly used to immobilize nucleic acids in southern blots and northern ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Oseltamivir phosphate is hydrolyzed in the liver to its active form and which is a potent and selective inhibitor of influenza virus neuraminidase. This enzyme is important for the entry of the virus into uninfected cells, the release of newly formed virus from infected cells, and the further spread of the infectious virus in the body. Thus, oseltamivir phosphate treats influenza by reducing ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Antibody Detection Raw Materials: SARS-CoV-2 infection can stimulate the body to produce specific antibodies. This means that researchers can determine whether a person has been infected with SARS-CoV-2 by detecting the presence of immunoglobulin G (IgG) or immunoglobulin M (IgM). IgG is the most abundant neutralizing antibody that persists in the blood from two weeks to four months after onset, ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
MRTX0902 is a potent SOS1 inhibitor which can be used for the therapeutic intervention of KRAS-driven (Kirsten rat sarcoma virus driven) cancers. Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with KRAS being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in human cancers and is present in 35% of lung adenocarcinomas ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
SARS-CoV-2 Detection Raw Materials: Nucleic acid detection, antigen detection and antibody detection are key tools for the diagnosis of COVID-19. Alfa Chemistry has the expertise and experience to provide you with the various raw materials needed in the diagnostic process. According to different detection methods, our products are classified as ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
The manufacture and composition of vaccines are complex and are strictly regulated to maximize potency and safety. In addition to antigens, vaccines also contain some important substances—vaccine excipients. Vaccine excipients comprise all chemical compounds used in the production of vaccines, such as vaccine stabilizers, vaccine emulsifiers, preservatives and vaccine ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Acetazolamide is a white to yellowish-white fine crystalline powder that is slightly soluble in acetone, insoluble in chloroform, diethyl ether and carbon tetrachloride. The chemical name of it is 2-acetamido-1,3,4-thiadiazole-5-sulfonamide. Acetazolamide is a first-generation carbonic anhydrase (CA) inhibitor, which is most commonly used in the treatment of glaucoma. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Catalysis and Reaction Mechanism Calculation: The reaction energy and reaction rate constant is analyzed through the atomic charge analysis of several important atoms participating in the reaction. In terms of complete reaction mechanism calculation, bond breaking, bond formation, transition state, and sometimes catalysis are necessarily taken into ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Generally, according to the source from which they are generated, pharmaceutical chemicals are considered as biobased (or natural), synthetic, or semi-synthetic. The natural environment remains a significant origin of novel therapeutic agent compounds. Biobased pharmaceutical chemicals are prepared from compounds found occurring in nature, containing active components in extract form obtained ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
As one of the best medicinal chemistry team in the world, Alfa Chemistry offer comprehensive medicinal chemistry support to biotech and pharmaceutical companies engaged in drug discovery and research. We can provide service for all stages of medicinal chemistry activities including hit generation and target validation, hit-to-lead optimization, lead optimization and preclinical development. We ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Drug Discovery and Research: Alfa Chemistry aims to support efforts to generate novel drugs by serving as a one-stop platform for the variety of services and expertise needed for drug discovery and development. We will collaborate through a combination of integrated, multidisciplinary drug discovery expertise and capabilities across modality targets, platforms and therapeutic areas. We use a ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Clinical Testing Laboratory: In order to provide an accurate and scientific basis for animal investigations, Alfa Chemistry's clinical testing laboratory performs clinical testing services such as animal biochemistry, hematology, coagulation, urinalysis, urine sediment microscopy, lymphocyte typing, in vitro hemolysis, and metabolite analysis. Our laboratory has highly automated tests and manual ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
In chemical concepts, dominant skeleton refers to the core structure of small molecules. In computational chemistry and medicinal chemistry, the skeleton also has the same meaning. The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of molecules, but also help pharmaceutical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
ORD Simulation Prediction: Optical rotation refers to when a beam of polarized light passes through a substance,the plane of polarized light rotates at a certain angle relative to its own direction of motion. The property of rotating polarized light that a substance has is called optical rotation. Materials with optical rotation include crystals, spin-polarized molecules and chiral molecules. For ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are improved by modifying the chemical structures of compounds ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Alfa CDMO's CRO offers custom services for research, optimization, and development phases of your project. ANTIBODY ENGINEERING CHEMICAL SYNTHESIS ANTIBODY DRUG CONJUGATION SCREENING ADC Assay and Mechanism Study Learn more: ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cyclophosphamide: Cyclophosphamide, also known as cytophosphane, appears as a white to almost white crystalline powder with a slightly bitter taste. The chemical name of it is p-[N,N-bis-(2-chloroethyl)]-1-oxo-3-nitrogen-2-phosphocyclohexane-p-oxide monohydrate. Cyclophosphamide is a synthetic alkylating agent chemically related to nitrogen mustard with antineoplastic and immunosuppressive ...