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Alfa Chemistry Medical Services In North America
61 services found
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Vibration Circular Dichroism (VCD) Spectrum Prediction: As a new method for measuring the circular dichroism of molecules in the infrared wavelength region, VCD has greatly expanded the application range of circular dichroism. Scientists use it to accurately predict chirality through conformational search and quantum chemical calculations, and the chromatogram of the vibrational circular ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Benzhexol hydrochloride is a class of antimuscarinic drug with the chemical name (±)-a-cyclohexyl-1-phenyl-3-(1-piperidinyl)-propanol hydrochloride. It was approved by the FDA for the treatment of Parkinson's disease (PD) in the United States in 2003. By improving muscle stiffness, benzhexol hydrochloride allows the body to move normally. Alfa Chemistry offers high quality benzhexol ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Drug Research Service Platforms: Due to Alfa Chemistry's deeply ingrained research and development capabilities, we have been able to advance technologically in both research and development. In addition, we have been able to provide an integrated service platform for our customers' novel medication development ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
All combinatorial library methods include the following three main steps: library preparation, library components screening, and chemical structures of active compounds determination. The goal of chemical compound library design is to reduce the number of molecules as well as maintain the diversity of the library. Combinatorial library therefore has the potential of finding leads more rapidly ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
The Alfa Chemistry platform integrates predictive methods with various computational techniques to accelerate drug discovery. Our iterative process is designed to accelerate evaluation and optimization of chemical matter in silico ahead of synthesis and assay. The most promising compounds emerging from each round of experimental project chemistry are then further optimized through additional ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Donepezil is a white or almost white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile, and practically insoluble in ethyl acetate and in n-hexane. Donepezil is a potent, selective, noncompetitive, and rapidly reversible inhibitor of acetylcholinesterase (AChEI) licensed for the treatment of ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Vaccine adjuvants are ingredients in vaccines added to improve the immune response after immunization. Modern vaccines usually contain only a portion of bacteria or viruses as their antigens and therefore require the help of adjuvants to induce a protective immune response. Vaccine adjuvants are of a diverse family, and hence, cannot be defined using a single integrated ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Phospholipids as Nucleic Acid Delivery Excipients: Phospholipids are unique and versatile molecules that are a key component of all cell membranes. A phospholipid consists of two basic parts: the hydrophilic head and the hydrophobic tail. The hydrophilic head consists of a glycerol molecule bound to a phosphate group. These groups are polar and are attracted to water. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Fluorouracil is a white to nearly white crystalline powder that is sparingly soluble in water and alcohol. The chemical name of it is 5-fluoro-2,4(1H,3H)-pyrimidinedione. Fluorouracil is a cytotoxic chemoradiotherapy medication used to treat rectal cancer, head and neck cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer by intravenous injection. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Tamoxifen citrate is an estrogen receptor antagonist and partial agonist which has been shown to induce apoptosis in human malignant glioma cells and to block VEGF production in breast cancer cells. Alfa Chemistry offers high quality tamoxifen citrate to customers which meets the CP & USP standards. Please feel free to contact us for APIs or technical services. Learn more at ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Calculation of Thermodynamic Data for Individual Chemical Reactions: Thermodynamic data for chemical reactions deals with the energy change in accordance with the laws of thermodynamics. This represents macroscopic properties of the system, that is the initial and final states not involving the mechanism. It is of great benefit to understand thermodynamic properties of chemical reactions for the ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
In chemical concepts, dominant skeleton refers to the core structure of small molecules. In computational chemistry and medicinal chemistry, the skeleton also has the same meaning. The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of molecules, but also help pharmaceutical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
ORD Simulation Prediction: Optical rotation refers to when a beam of polarized light passes through a substance,the plane of polarized light rotates at a certain angle relative to its own direction of motion. The property of rotating polarized light that a substance has is called optical rotation. Materials with optical rotation include crystals, spin-polarized molecules and chiral molecules. For ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are improved by modifying the chemical structures of compounds ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Alfa CDMO's CRO offers custom services for research, optimization, and development phases of your project. ANTIBODY ENGINEERING CHEMICAL SYNTHESIS ANTIBODY DRUG CONJUGATION SCREENING ADC Assay and Mechanism Study Learn more: ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cyclophosphamide: Cyclophosphamide, also known as cytophosphane, appears as a white to almost white crystalline powder with a slightly bitter taste. The chemical name of it is p-[N,N-bis-(2-chloroethyl)]-1-oxo-3-nitrogen-2-phosphocyclohexane-p-oxide monohydrate. Cyclophosphamide is a synthetic alkylating agent chemically related to nitrogen mustard with antineoplastic and immunosuppressive ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Vaccine Stabilizers: Successful vaccine stabilization strategies include both empirical efforts to screen and identify appropriate stabilizers and environmental conditions and more rational approaches toward developing an understanding of the causes and mechanisms of vaccine inactivation. Among these, determining the appropriate stabilizer is a critical means of maintaining vaccine potency and ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Vaccine Emulsifiers: Emulsifiers, also known as surfactants, can reduce the surface tension of the liquid, thereby increasing the diffusion and wetting properties. An emulsifier consists of a polar (or hydrophilic) head and a hydrophobic tail which can be dissolved in both polar and non-polar solvents. These emulsifiers have physicochemical properties of self-aggregation, solubilization or ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Epalrestat is a carboxylic acid derivative and a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy, which is one of the most common long-term complications in patients with diabetes mellitus. Alfa Chemistry offers high quality epalrestat to customers which meets the CP & JP standards. Please feel free to contact us for APIs or technical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Tofacitinib citrate, chemically named as (3R,4R)-3-[4-methyl-3-[N-methyl-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropionitrile citrate, is a white or almost white powder, which is lightly soluble in water, very slightly soluble in methanol, and practically insoluble in acetone. Tofacitinib citrate is a novel, oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid ...