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Brain Barrier Services
12 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
They extend their processes along capillaries, pre-capillary arterioles and post-capillary venules. Pericytes regulate blood-brain barrier (BBB) permeability, angiogenesis, clearance, cerebral blood flow (CBF), neuroinflammation and stem cell ...
by:EnClear Therapies based inNewburypor, MASSACHUSETTS (USA)
Localized CNS delivery of therapeutics & monitoring of CSF to ensure effective & personalized ...
by:SonALAsense based inBerkeley, CALIFORNIA (USA)
Glioblastoma multiforme (GBM) patients face a dismal prognosis, with recurrence virtually inevitable. RGBM has no currently effective means of ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Certain proteins including α-synuclein can form disease-specific fibrillar amyloid aggregates. The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded proteins or ...
Manufactured by:NeoClone based inMadison, WISCONSIN (USA)
NeoClone is fast becoming a leader in the single domain antibody library field. We offer a wide range of unique services, including construction of immunized single domain antibody libraries using our llamas, bio-panning of naïve or immunized single domain antibody libraries and large scale production of single domain antibodies ...
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
Pion Analytical Services offers comprehensive support for drug development activities by providing sophisticated assays, analyses, and interpretations that help in understanding pharmacokinetic parameters at an early stage in the development process. With our advanced instrumentation, in vivo-level insights can be obtained in vitro. Our services include establishing primary characteristics of ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Including Pharmacokinetics and Immunogenicity. Designed to be an extension of your laboratory, Nexelis, a Q² Solutions Company, supports bioanalysis in all phases with agile assay development to validation mindset. Whether we design a custom bioanalytical assay or support a client’s technology transfer, our method development process results in an optimized assay compliant with global ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Parenteral formulation development for drugs delivered by injection or infusion is the fastest and the second most common route of drug administration. These formulations must achieve good compatibility of the drug substances with the excipients and the primary container. Successful formulation development can determine drug patentability, lifecycle, and overall market success. With growing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Endocannabinoids are amphipathilic molecules synthesized from phospholipids in the nervous system. They are a part of the endocannabinoid system, which includes G protein-coupled receptors. The most extensively studied endocannabinoids are N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Parenteral formulation development for drugs delivered by injection or infusion is the fastest and the second most common route of drug administration. These formulations must achieve good compatibility of the drug substances with the excipients and the primary container. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in cellular function. Receptors are categorized based on their cellular location into cell surface receptors and intracellular receptors. Each receptor typically has two active sites: one that recognizes and binds to the ligand and another ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...