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- FluidFM for CRISPR cell line development Accelerate your CRISPR gene editing and cell line engineering
- Single-cell omics with Live-seq
- Mechanobiology and single-cell adhesion measurements with FluidFM
- FluidFM for Neuroscience Pattern, stimulate, inject into, and analyze single neurons
- FluidFM for Virology Study viral entry and replication on a single virion-single cell level
- Excitation-Contraction-Energy (ECE) Coupling Analysis for Cardiac Physiology
Disease Modeling Services Available In In Canada
29 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
It is indispensable and effective to use animal disease models in experimental medical research. Animal models of neurological disease provide a convenient and reliable platform for developing new therapies and drugs for such diseases. Creative Bioarray uses animal models of different ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
In vitro retinal disease modelling for retinal therapy. Newcells offers a fast and reliable in vitro safety and efficacy service for the evaluation of novel compounds for retinal therapy using complex human retinal organoid or RPE models developed in house. Both models are iPSC derived allowing gene-edited lines to be engineered ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
We mainly use the three approaches to abrogate gene function in zebrafish: stable lines carrying mutations (mutants); morpholino-based knock-down of gene function; and use of CRISPR/Cas9 gene editing to disrupt gene function in injected embryos. Many human pathological conditions from Alzheimer's disease to metabolic syndrome have been successfully modelled in ...
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio has a repository of iPSC’s for disease modeling and proprietary technologies for differentiating these cells into myoblasts and cardiomyocytes. Curi has developed in vitro 3D disease models for multiple disease phenotypes. In addition, Curi has the capability of generating new gene-edited iPSC ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has long-standing experience in conducting preclinical zebrafish model studies of cardiovascular disease. We offer consultancy and preclinical zebrafish models of cardiovascular disease including hypertension, arrhythmia, heart failure and atherosclerosis, etc. Similar to other animal models, ...
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio’s iPSC Repositories Available for Services. Custom Panel of Different Gender and Ethnicities. Disease Model Pairs. Patient-derived iPSC-lines. Isogenic DMD/WT Myoblasts. Isogenic DMD/WT ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Rodent disease models are widely used for a broad range of project objectives, which involve investigation of pathological process and mechanism of disease, pre-clinical tests of potential therapeutic agents, ...
Manufactured by:TissUse GmbH based inBerlin, GERMANY
TissUse offers high-value service contracts to create custom solutions for safety evaluation of drugs, cosmetics and chemicals, and pre-clinical human disease modelling. Any new chip design serving customer needs with a specific organ arrangement can be prototyped and produced at short notice due to a proprietary rapid prototyping procedure established at ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We work with partners to develop new disease models and new biomarkers of disease. We can also use our disease models to identify new drug targets and screen chemical compounds to identify potential new drug candidates. CENTOGENE provides companies with tools to accelerate drug discovery. From population ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current ...
Manufactured by:SCIREQ - an emka TECHNOLOGIES Company based inMontreal, QUEBEC (CANADA)
VAAD is a new innovative technique using the flexiVent, introduced to improve in vivo aerosol administrations for drug delivery and disease modelling. The VAAD approach minimizes subject-to-subject variability, and fosters a highly homogenous aerosol deposition within the lung. This optimized aerosol protocol is synced with mechanical ventilation to standardize ...
Manufactured by:Cytosurge AG based inGlattbrugg, SWITZERLAND
Custom CRISPR cell line engineering service based on our FluidFM® ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both side-effect profiling and efficacy according to your requirement. ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to ...
Manufactured by:SCIREQ - an emka TECHNOLOGIES Company based inMontreal, QUEBEC (CANADA)
Surgical skills are needed for all our implanted telemetry and for some in vitro isolated organs ...
by:Selvita S.A. based inKrakow, POLAND
Having experience in both pharma and biotech R&D, we are well aware of what it means to discover a hit and transform it into a drug. You can best benefit from this “insider” experience through our integrated drug discovery services built ...
Manufactured by:Destiny Pharma plc based inBrighton, UNITED KINGDOM
Work on earlier programmes investigating infections in areas such as respiratory, dermal, ocular and biofilms carries on as research projects, including academic and/or commercial collaborations and grant funded ...
by:elminda Ltd. based inHerzliya, ISRAEL
CNS drugs exhibit the lowest approval success rates due to multiple challenges such as lack of efficacy in early and advanced stages of development, Poor target selection / engagement, poor translation from pre-clinical models and disease heterogeneity. BNA may contribute in CNS research and drug development by adding new objective endpoints, assisting in ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
In vitro and in vivo methods to provide a study setup that thoroughly determines safety and efficacy. ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Custom In Vivo Models and Testing Solutions. Selecting the appropriate in vivo model for your assays is critical for the success of your preclinical research program. At Nexelis, a Q² Solutions Company, we designed and developed disease specific in vivo models alongside bespoke personalized model development ...