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Creative Biogene Disease Modeling Services
3 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
We mainly use the three approaches to abrogate gene function in zebrafish: stable lines carrying mutations (mutants); morpholino-based knock-down of gene function; and use of CRISPR/Cas9 gene editing to disrupt gene function in injected embryos. Many human pathological conditions from Alzheimer's disease to metabolic syndrome have been successfully modelled in ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has long-standing experience in conducting preclinical zebrafish model studies of cardiovascular disease. We offer consultancy and preclinical zebrafish models of cardiovascular disease including hypertension, arrhythmia, heart failure and atherosclerosis, etc. Similar to other animal models, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current ...