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Human Disease Services In North America
24 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Drug discovery has been considered as a high-cost and time-consuming process to treat different kinds of human ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The nucleic acid drug, as a novel therapeutic modality, can achieve long-lasting or even curative effects via gene regulations, replacement or editing. They have great potential to treat human diseases such as viral infections, cancers, and genetic ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Recently developed CRISPR/Cas9-based screening methods have great potential for revealing the mechanisms and treatment strategies of human diseases, but there are still some biological studies that are not suitable for CRISPR knockout screening. CRISPRa and CRISPRi screening opens up many new possibilities. CRISPR/Cas9 PlatformCB provides custom libraries for ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Drug discovery and development is an attractive strategy for treating various human diseases. In particular, different types of drugs, such as vaccines, antibodies, have been generated and tested in many preclinical and clinical trials. ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
The development of human disease is very complex, to itself as experimental object to in-depth study of the mechanism of disease, the accumulation of clinical experience not only in time and space are limited and many experiments on the moral are restricted. Animal models can provides the basic platform for the study of safety research of drugs, ...
by:Amgen Inc. based inThousand Oaks, CALIFORNIA (USA)
Understanding the fundamental biological mechanisms of disease is a defining feature of Amgen's discovery research efforts—and a major contributor to the development of Amgen's deep and broad pipeline of potential new medicines. Amgen's "biology first" approach permits its scientists to first explore the complex molecular pathways of disease before ...
by:The Ecological Society of America (ESA) based inWashington, DISTRICT OF COLUMBIA (USA)
Ecologists have discovered that many plants and animals produce chemicals that protect them from predators and diseases. Some of these same chemicals have been synthesized by scientists or harvested from the organism and used to treat human diseases. For example, the Pacific Yew tree produces a substance which is used in cancer treatments. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs is focusing on the model animal genome targeted transformation technology, contributing to building models of human diseases, functional genomics research, and drug screening services and related products. Creative Biolabs offers vectors for transgene expression in a variety of species including mammals, zebrafish, Drosophila, plants, bacteria, ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Strict control of enzyme activity is essential for homeostasis. Any malfunction of key enzymes (mutation, overproduction, underproduction or deletion) can lead to diseases. Therefore, enzymes have long been considered as important drug targets for the treatment of major human ...
by:Nautilus Biotechnology based inSeattle, WASHINGTON (USA)
As we begin to scratch the surface of the true complexity and nuance of human health and disease, a breakthrough increase in proteomics analysis throughput will allow researchers to measure at the scale needed to power the studies needed to quickly and cost effectively discover these new diagnostic ...
by:Doris Duke Charitable Foundation (DDCF) based inNew York, NEW YORK (USA)
Doris Duke was a significant supporter of medical research, making contributions to hospitals and research centers throughout her life. In her will, she expressed her interest in supporting “medical research designed to effectuate cures of major diseases.” ...
by:Vertex Pharmaceuticals based inBoston, MASSACHUSETTS (USA)
Vertex is focused on discovering, developing and commercializing innovative medicines so people with serious diseases can lead better lives. Our scientists don’t see the impossible as an obstacle; they see it as a good place to start. These studies are investigating treatments or outcomes that have not all received approval from a health authority. The information presented is not intended ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, ...
Manufactured by:Galera Therapeutics, Inc. based inMalvern, PENNSYLVANIA (USA)
The cornerstone of our work is the recognition that oxygen metabolic pathways play important roles in human biology and ...
Manufactured by:nVector based inPhoenix, ARIZONA (USA)
The direct medical costs and indirect costs of TBI, such as lost productivity, totaled an estimated $60 billion in the US for the year 2000 (Source: US Department of Health and Human Services, Centers for Disease Control and Prevention, ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
EX VIVO Human Platforms for Cardiovascular Drug Discovery. Broadly defined, cardiovascular disease is the leading cause of death for men and women across most racial and ethnic groups in the United States with one person dying approximately every 34 seconds1. To drive successful clinical translation of new cardiovascular medicine, AnaBios develops relevant ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Humanized mice broadly refers to mice expressing human genes via transgenesis to gain relevant insights in the in vivo context for the understanding of human-specific physiology and pathology. Whilst many basic biological insights have been obtained from mouse studies, there are limitations to mouse models when investigating human biology. There are components of mouse biology systems that are ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
On the basis of extensive experience in peptide synthesis, Creative Peptides proudly offers the most comprehensive glycopeptides synthesis services to our worldwide clients. Our scientists are committed to deliver high quality glycopeptides which will go through strict mass spectral and HPLC analysis to meet our customers’ demands. ...