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Therapeutic Potential Services
20 services found
Manufactured by:Sartorius AG based inGoettingen, GERMANY
Unlock the full therapeutic potential of your biopharmaceuticals. Albumin is a well-documented, safe, multifunctional formulation excipient for biopharmaceuticals and advanced therapies enabling it to address key formulation and stability challenges not possible with classical formulation strategies. ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
The field of bioconjugation has had a considerable impact on academic research, clinical diagnostics and the production of therapeutics. Peptides are an important type of molecules for derivatization by bioconjugation. Peptide–drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving ...
Manufactured by:RoosterBio, Inc. based inFrederick, MARYLAND (USA)
As a raw material in emerging cell, gene, and exosome based therapies, understanding the key quality attributes of your hMSC, such as phenotype, function, and growth kinetics are vital to understanding expansion and therapeutic potential. At RoosterBio Inc., we have years of experience in hMSC isolation, manufacturing, and characterization. Leverage this ...
by:Oncodesign based inDijon, FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign has been a player known for its ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
While the normal expression and function of miRNAs are vital for physiological processes, aberrant expression of miRNAs has been proved to be closely related to the occurrence of various cancers. Perturbation of endogeneous miRNAs helps to study the function of specific miRNAs and holds the potential for therapeutics. Synbio Technologies offers a wide range of ...
by:Bionique Testing Laboratories, Inc. based inSaranac Lake, NEW YORK (USA)
Resistance to antibiotics whether inherent or acquired is a well known characteristic of mycoplasmas. The antibiotic sensitivity profile developed in this assay provides information regarding potential therapeutic agents targeted for an individual. Sample Requirements: Test sample must currently be on test by a direct culture method at ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Rodent disease models are widely used for a broad range of project objectives, which involve investigation of pathological process and mechanism of disease, pre-clinical tests of potential therapeutic agents, ...
by:Genome Biologics based inFrankfurt am Main, GERMANY
Therefore, regenerative approaches to replenish the lost cardiomyocytes are necessary to recover the contractile capacity of the heart and prevent death. Targeting cardiomyocyte proliferation is a potential new therapeutic strategy for myocardial regeneration and repair. Using our platform, we have uncovered novel therapeutic RNAi approaches that ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Primary T cell, as an important class of immune cells system, play an extremely important role in immunity system. It holds great potential for therapeutic applications to engineer genome in primary T cells. However, genome engineering in primary T cells is still a challenge due to low delivery efficiency and limited expression of CRISPR/Cas9 components. In order ...
Manufactured by:NaviGate Cardiac Structures, Inc., (NCSI) based inLake Forest, CALIFORNIA (USA)
Tricuspid Valve insufficiency (regurgitation) is a medical condition where the valve between the right ventricle (pumping chamber) and the right atrium does not close properly. This allows blood to reverse instead of moving towards the pulmonary artery for reoxygenation in the lungs. As this condition worsens, blood is backed up and creates edema of the lower extremities, damage to ...
Manufactured by:Sage Therapeutics based inCambridge, MASSACHUSETTS (USA)
Sage stepped up to fill an innovation void by thinking differently about brain health disorders and how we approach the discovery and development of new ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
EX VIVO Human Platforms for Cardiovascular Drug Discovery. Broadly defined, cardiovascular disease is the leading cause of death for men and women across most racial and ethnic groups in the United States with one person dying approximately every 34 seconds1. To drive successful clinical translation of new cardiovascular medicine, AnaBios develops relevant human ex vivo platforms for many ...
by:Oncodesign based inDijon, FRANCE
EXPLORE, a new service to identify and validate therapeutic targets, primarily cancer treatments – an area of expertise and excellence at Oncodesign to discover and investigate preclinical proofs of concept involving a wide variety of different approaches and anti-cancer mechanisms of action. EXPLORE, is the combination of our OncoSNIPER platform and a tailored and well established ...
Manufactured by:Kura Oncology, Inc. based inSan Diego, CALIFORNIA (USA)
Kura Oncology’s clinical trial programs represent the next step toward our goal of realizing the full potential of precision medicine. Our investigational trials are studying innovative therapeutic candidates with the potential to help patients with certain cancers live better, longer lives. ...
Manufactured by:Creative BioMart based in, NEW YORK (USA)
Creative Biomart provides drug analysis service for pre-clinical drugs and natural products on their physical and chemical properties. Our services include three main assays: pre-clinical pharmaceutical property analysis, pharmacokinetics analysis & bioanalysis, andnatural product ...
by:PharmaBiome AG based inSchlieren, SWITZERLAND
Solid research shows that the smallest relevant biological unit of the microbiome is function, delivered by a network of intestinal bacteria. Bacteria need to interact in a functional network and achieve a balance so that the microbiome can ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
Acute Radiation Syndrome (ARS) involves severe, potentially lethal damage to the bone marrow’s ability to produce blood cells, as well as to other systems and organs. Severe damage to bone marrow makes victims vulnerable to life-threatening hemorrhage, infection and anemia. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Humans are highly organized systems comprised of approximately 3.72×1013 cells of various types, which maintain proper organ function and normal cellular homeostasis. Despite significant and revolutionary discoveries in the field of cell biology, the heterogeneity of cells still requires further investigation. Single-cell RNA sequencing (scRNA-seq) has become the latest method for revealing the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Drug affinity responsive target stability is a label-free small molecule probe technique under chemical proteomics first proposed by Lomenick et al. in 2009, which makes it possible to track and identify target proteins whose stability changes after binding with small molecules. To date, Drug affinity responsive target stability has been a focus in tracking proteins in animals, fungi, bacteria, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...