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Drug Development Services In Massachusetts
38 services found
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
Pion Analytical Services offers comprehensive support for drug development activities by providing sophisticated assays, analyses, and interpretations that help in understanding pharmacokinetic parameters at an early stage in the development process. With our advanced instrumentation, in vivo-level insights can be obtained in vitro. ...
Manufactured by:Ariana Pharma based inParis, FRANCE
Using our pioneering eXplainable AI platform KEM® we design and execute Precision Medicine clinical trials, with an unparalleled successful track record across multiple therapeutic areas. Thanks to our XAI KEM® platform we integrate extensive pre-clinical, clinical as well as Real World Evidence data, to define best dose, identify patient selection and surrogate endpoint biomarkers as ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibody drug developability analysis (drugability analysis) is a key strategy used to evaluate the development prospect of candidate antibody drug. This analysis is based on a comprehensive evaluation of multiple aspects of the candidate antibody, including biological activity, pharmacology, pharmacokinetics, safety, and ...
by:Pace Analytical based inRoseville, MINNESOTA (USA)
In early-phase gene therapy development, we work with you to determine the most reliable analytical methods to provide the data needed to guide effective development decisions. Next, we deliver a robust assessment of the physicochemical and biophysical characteristics of the therapeutic ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Drug screening refers to the evaluated process of substances (samples) potentially used as drugs, assessing their biological activity, pharmacological effects, and therapeutic value through appropriate methods. This process encompasses biochemical and cellular levels of screening, divided into high-throughput screening (HTS) and virtual ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Many drugs target proteins that function as receptors for small-molecule ligands. These ligands bind to and alter the structures of their protein targets, thus modulating their biological activities. Key protein targets in the fields of biology and pharmaceutical research include the nuclear receptors (NRs) that belong to the superfamily of ligand-dependent transcription factors, the ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro’s early clinical imaging services deliver decision-making data for drug development teams in Phases 0, I and II. We have many years of pharma industry experience, and this understanding of the drug development process helps us design and execute pathology and imaging studies so that the resultant data reduces risk ...
Manufactured by:Novo Nordisk A/S based inBagsværd, DENMARK
Drug development works best as a team endeavor. We continuously explore strategic collaborations to advance our pipeline toward commercialization and to further our work in the treatment of both rare diseases and common diseases that have a genetic component. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Humans are highly organized systems comprised of approximately 3.72×1013 cells of various types, which maintain proper organ function and normal cellular homeostasis. Despite significant and revolutionary discoveries in the field of cell biology, the heterogeneity of cells still requires further investigation. Single-cell RNA sequencing (scRNA-seq) has become the latest method for revealing the ...
by:Pace Analytical based inRoseville, MINNESOTA (USA)
Our understanding of domestic and international biotech and pharmaceutical operations and of the regulatory challenges facing these industries allows our experts to provide comprehensive support across the drug development pipeline. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
One of the main obstacles in drug development is how to deliver drugs effectively to target cells. In general, macromolecules such as proteins and mRNA cannot penetrate the cell membrane because the cell membrane has acquired protective mechanisms through evolution. ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro has a vast range of tools that help accelerate your drug discovery and development process. Our technology platforms support key decision-making in: Early discovery and screening. Candidate selection. First-in-human translation and early development. Late stage, multi-center determination of ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Target validation is an essential and critical phase of the drug discovery process. This is a crucial step before starting to develop a treatment based on a targeted protein that has been identified to play a role in the disease. The target protein’s role must be clearly identified before starting to develop a drug ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
With the rapid development of biotechnology, drug research and development has gradually entered a new era of precision and personalization. Targeted Protein Degradation (TPD) drugs are an emerging therapeutic strategy that utilizes the body's ubiquitin-proteasome system to degrade specific pathological proteins to achieve ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
A key step in drug discovery is target identification—identifying "druggable" biological targets. After a target is identified, it must be validated to demonstrate the functional relationship between the target and disease phenotype while ensuring safety. The drug discovery process is lengthy and costly, but good target validation increases the likelihood of ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
At Revvity, we work with you to expedite the development of gene therapy vectors. ...
Manufactured by:Sage Therapeutics based inCambridge, MASSACHUSETTS (USA)
Sage stepped up to fill an innovation void by thinking differently about brain health disorders and how we approach the discovery and development of new ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro is an medical imaging CRO with over 210 scientists, 60+ PhD’s and MD’s and 2100+ qualified imaging centers across the globe. We possess scientific and regulatory expertise, project management scale and operational excellence to manage all the clinical trial imaging components of your Phase I-IV clinical trials across the therapeutic spectrum and spanning imaging ...
Manufactured by:Akebia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Tenacity: At Akebia, we are inspired to think boldly and move bold thinking into action. We leverage our scientific expertise and this innovative thinking to develop clinical advances in areas that are important to people living with kidney disease. We thrive as collaborators because we believe that we can go further together. We work with partners across the globe to pioneer and grow new areas ...