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Cytokine Expression Articles & Analysis

15 articles found

Exploring the Rat Cytokine and Chemokine Panel for Immune Research

Exploring the Rat Cytokine and Chemokine Panel for Immune Research

What Are Cytokines and Chemokines? Cytokines are small proteins secreted by cells that have a profound influence on the behavior of other cells. ...

ByCreative Proteomics


GMP Grade Cytokine Needed for Cell Therapy Manufacturing

GMP Grade Cytokine Needed for Cell Therapy Manufacturing

GMP growth factors and cytokines designed for therapeutic manufacturing are an essential component of defined media. ...

ByCreative Bioarray


Research Progress on Aluminum Adjuvants and Their Mechanisms of Action

Research Progress on Aluminum Adjuvants and Their Mechanisms of Action

Binding of adjuvants to antigens can increase the surface area of the antigen, and the biological effects include (1) deposit effect of antigen; (2) upregulation of cytokine and chemokine expression, and recruitment of immune cells at the injection site; (3) activation of inflammasome; and (4) carrier effects. ...

ByBOC Sciences


Cytokines in CAR-T Cell Therapy

Cytokines in CAR-T Cell Therapy

Compared with traditional chemotherapy and hematopoietic stem cell transplantation, it is more precise in killing tumor cells and significantly reduces toxic side effects while improving efficacy. Cytokines in CAR-T cell therapy Cytokines are pleiotropic and diverse, and enhancing T-cell activation signaling by transgenic expression of ...

ByCreative Proteomics


Peptide Vaccine Design

Peptide Vaccine Design

Most adjuvants induce local inflammation at the site of administration, recruiting various cytokines and chemokines and stimulating CCR7 expression on APCs to facilitate antigen migration to lymph nodes. ...

ByCreative Peptides


The Crucial Role of Cytokines in Biomedical Research and Drug Development

The Crucial Role of Cytokines in Biomedical Research and Drug Development

Cytokines Applications Cytokines are a type of signaling protein that primarily regulates a series of biological functions by binding to specific receptors. ...

ByBeta Lifescience


Autoimmune Diseases Targets

Autoimmune Diseases Targets

Both mouse and human TSLP are predominantly expressed by epithelial cells, with the highest expression levels observed in the lung, skin, and intestine[2]. ...

ByBeta Lifescience


GMP Grade Cytokine Needed for Cell Therapy Manufacturing

GMP Grade Cytokine Needed for Cell Therapy Manufacturing

GMP growth factors and cytokines designed for therapeutic manufacturing are essential components of defined media. ...

ByCreative Bioarray


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Hyperglycemia in conjunction with dyslipidemia induces insulin resistance and provokes release of proinflammatory cytokines resulting in chronic inflammation, accelerated lipid peroxidation with further development of atherosclerotic alterations and diabetes. ...

ByVeriSIM Life


A Novel, High-Throughput Platform to Characterize Novel IBD Therapeutics

A Novel, High-Throughput Platform to Characterize Novel IBD Therapeutics

Tumor Necrosis Factor Alpha (TNF-a) is a potent cytokine that is over-expressed by cells during chronic intestinal inflammation. ...

ByAltis Biosystems


Protein Acetylation and Ubiquitination Interactions Control MCL1 Protein Stability

Protein Acetylation and Ubiquitination Interactions Control MCL1 Protein Stability

Accumulating evidence suggests that multiple growth factors and cytokines induce mcl1 gene expression, multiple microRNAs and lncRNAs control the stability of mcl1 mRNA, and mTORC1 promotes the translation of mcl1 protein. ...

ByCreative BioMart


mRNA Delivery System

mRNA Delivery System

At the same time, foreign mRNA can also activate the expression of pro-inflammatory cytokines such as interferon. Classification of mRNA delivery systems 1. ...

ByBOC Sciences


Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota

Effects of oral administration ofL. rhamnosus KBL365 orL. paracasei KBL382 on innate cytokine and chemokine expression in the skin of AD mice. (A) Thymic stromal lymphopoietin (TSLP), (B) thymus and activation regulated chemokine (TARC) and (C) macrophage-derived chemokine (MDC) were analyzed through real-time PCR. ...

ByKoBioLabs


Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

Administration of Lactobacillus fermentum KBL375 Causes Taxonomic and Functional Changes in Gut Microbiota Leading to Improvement of Atopic Dermatitis

Effects of L. fermentum KBL375 on the Expression of Cytokines or Chemokines in Skin From the in vivo AD Model Figure 3 shows the effects of L. fermentum KBL375 treatment on the expression of innate cytokine TSLP or chemokines including MDC or TARC in skin in the in vivo AD model. ...

ByKoBioLabs


Somatic Excision Demonstrates that c-Jun Induces Cellular Migration and Invasion through Induction of Stem Cell Factor

Somatic Excision Demonstrates that c-Jun Induces Cellular Migration and Invasion through Induction of Stem Cell Factor

The reduced migratory velocity and migratory directionality was rescued by either c-Jun reintroduction or addition of secreted factors from wild-type cells. An unbiased analysis of cytokines and growth factors, differentially expressed and showing loss of secretion upon c-jun deletion, identified stem cell factor (SCF) as a c-Jun target gene. ...

ByAmerican Society for Microbiology (ASM)

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