Cytokine Expression Articles & Analysis
5 news found
Senti Bio has developed a novel calibrated release interleukin-15 (crIL-15) technology to enable both autocrine cytokine signaling (to increase CAR-NK cell proliferation and persistence) and paracrine cytokine signaling (to stimulate the patient’s surrounding immune cells). ...
Obsidian Therapeutics, Inc., a biotechnology company pioneering engineered cell and gene therapies, today announced it will present data highlighting the potential of the company’s cytoDRiVE® platform technology, which allows regulation of protein expression using small molecule drugs. The data to be presented demonstrate tight control of membrane bound or shed IL12 (a ...
[xii] In addition, zapnometinib has the potential to modulate the immune response, thus avoiding an overshooting cytokine/chemokine response that can be caused by viral infections. MEK inhibition can reduce the gene expression of some of the cytokines / chemokines involved, including TNF-α, IL-1ß, IP-10, IL-8, MCP-1 and ...
· Reporter-encoding Oncolytic Virus Reporter-encoding oncolytic viruses allow accurate tracking of gene expression, tumor metastases, viral infection, and assessment of gene therapy. ...
” The researchers developed their unique data by following a group of healthy volunteers (135) for nine years, taking annual blood samples which were profiled against a range of ‘omics’ technologies (cell subset phenotyping, functional responses of cells to cytokine stimulations and whole blood gene expression). This captured population- and ...