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Cytokine Chemokine Equipment & Supplies
24 equipment items found
Manufactured by:PsiOxus Therapeutics Ltd. based inAbingdon, UNITED KINGDOM
Four transgenes: Producing an anti-FAP bispecific plus cytokines/chemokines. Currently in clinical trials in the US and UK. See our clinical trials page for more information. The aim of this study is to characterise the safety, tolerability and preliminary efficacy of NG-641 in patients with metastatic or advanced epithelial ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated ...
Manufactured by:Kaneka Eurogentec S.A. based inSeraing, BELGIUM
Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
Our therapies are focused on leveraging the inherent biological capabilities of gamma delta T cells (GDT cells) together with an integrated cell engineering approach. GDT cells are a component of the lymphocytes (white blood cells) present within all humans, representing approximately 1-5% of the circulating population. As part of the immune system's innate response, their natural properties make ...
Manufactured by:Estar Medical UK Ltd based inHarrow, UNITED KINGDOM
Cellenis® Pure PRF, is a second generation of platelet concentrate and consists of an autologous polymerized fibrin scaffold comprised of large quantities of platelets, cytokines, growth factors and chemokines. As the fibrin matrix is better organized, it is able to efficiently direct stem cell migration and the healing cascade. Cellenis® Pure PRF is ...
Manufactured by:Direct Biologics based inAustin, TEXAS (USA)
Extracellular vesicles (EVs) are nature’s communication tool to coordinate activities between cells within your body. EVs are small lipid membrane-bound particles which contain molecular signals (proteins and RNA) that act like a message in a bottle. After their release from a cell, they are received by other cells which then respond to their molecular messages. This enables the tissues ...
Manufactured by:Stem Pharm, Inc based inMadison, WISCONSIN (USA)
Stem Pharm’s advanced neural organoid models uniquely contain microglia and provide new opportunities to investigate CNS disease modeling, drug discovery, and toxicology applications. ...
Manufactured by:Epithelix based inPlan-les-Ouates, SWITZERLAND
SmallAir™ is an in vitro cell model of the human small airway epithelium cultured at the air liquid ...
Manufactured by:Epithelix based inPlan-les-Ouates, SWITZERLAND
MucilAir is an in vitro cell model of the human airway epithelium cultured at the air liquid ...
Manufactured by:Origin, Inc based inPrinceton, NEW JERSEY (USA)
Nitric Oxide (NO) was first prepared in 1620 and first studied in 1720. It was poorly understood until the late 1900s. The discovery of the role of NO as fundamental to biologic function was so remarkable that hundreds of research papers led Nitric Oxide to be proclaimed "molecule of the year" in 1992 by the journal Science. Three NO researchers shared the 1998 Nobel Prize in Physiology or ...
Manufactured by:CytoSorbents Corporation based inMonmouth Junction, NEW JERSEY (USA)
The CytoSorb adsorber is a CE-marked Class IIb medical device that is specifically approved for the removal of cytokines, bilirubin and myoglobin. Next to this CytoSorb is indicated for use intraoperatively during cardio-pulmonary bypass surgery for the removal of P2Y12-Inhibitor Ticagrelor and/or Factor Xa-Inhibitor. It is approved for use with standard hemodialysis-, hemofiltration-, ECMO- and ...
Manufactured by:Fate Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
The oncology therapeutic landscape has been transformed with the use of checkpoint inhibitor therapy. Despite the clinical benefit conferred by approved checkpoint inhibitor therapy against a variety of tumor types, these therapies are not curative and, in most cases, patients either fail to respond or their disease progresses on these agents. Resistance to checkpoint inhibitor therapy has been ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sodium metatungstate (Sodium polyoxotungstate) is a NTPDase inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively[1]. Sodium metatungstate has anti-inflammatory and anti-cancer effect. Sodium metatungstate inhibits ATP breakdown but also blocks central synaptic ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. TL8-506 has immunomodulatory effects and can be used in the study of tuberculosis and cancer ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, ...
Manufactured by:Estar Medical UK Ltd based inHarrow, UNITED KINGDOM
Tropocells® Pure PRF (Platelet Rich Fibrin) is an autologous polymerised fibrin scaffold consists of large quantity of platelet cytokines, growth factors and chemokines. Tropocells® Pure PRF creates a fibrin scaffold with which the growth factors and other bioactive materials interact to stimulate the healing process. The Tropocells® pure PRF is ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. ...
Manufactured by:Sanuwave and Sanuwave Health, Inc. based inSuwanee, GEORGIA (US) (USA)
PACE® Therapy Offers Patients the Best Chance of Healing: Use Energy First. Diabetic patients that develop chronic wounds have comorbidities that can make healing difficult. They deserve the greatest chance for accelerated wound healing. Our leading, end-to-end, advanced wound care solution, SANUWAVE’s dermaPACE System activates the body’s normal regenerative processes, expedites ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A*02:01 (a melanoma-associated antigen). Tebentafusp guides T cells to kill gp100-expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain. Tebentafusp leads to inflammatory cytokines and cytolytic proteins production, resulting in the direct lysis of ...