Refine by
Drug Induced Equipment & Supplies
42 equipment items found
Manufactured by:Demei Pharmaceutical Technology Co., Ltd. based inShijiazhuang City, CHINA
Its antidiuretic effect is more powerful and lasting than vasopressin, but it has no vasoconstrictive effect and little side effects. It is clinically used for congenital or drug-induced platelet dysfunction and uremia. Can be used for controlling and preventing bleeding during minor surgery; Central diabetes insipidus, etc.Desmopressin acetate preparation is ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Newcells now offers the first fully differentiated, primary podocyte model derived from fresh kidney tissue for the in vitro assessment of drug-induced glomerular toxicity. The effect of a drug on the glomerular filtration barrier and podocyte glomerular permeability can now be easily evaluated in vitro. Podocyte injury and proteinuria can be ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Fluorescence-based assays with iPSC-derived cardiac and neuronal models can be used to monitor short and long-term drug-induced changes on calcium transients. Our scientists develop the most optimal calcium transient assay for each project and can scale it up for high-throughput screening, to accurately evaluate efficacy and safety of drug ...
Manufactured by:RheoMeditech Inc. based inSeoul, SOUTH KOREA
The Anysis system test provides assessment for inherited, acquired, or drug-induced platelet dysfunction. Through in-vivo vascular mimicking microfluidics, the system measures a realistic primary hemostasis associated with platelet ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Our team can manufacture endothelial cells from the iPSC line that best fits your project with a controlled and scalable process. Custom assays can be developed with this fully functional cell model to screen drug-induced effects on endothelial barrier permeability or 3D capillary tube ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Evaluate drug candidate toxicity at clinically relevant concentrations in a co-culture human kidney model. Predicting drug-induced kidney toxicity and drug-drug interactions continues to be a challenge due to a reliance on immortalized cell line culture or animal models that do not translate to human response. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Orazamide is an AICA orotate. Orazamide can prevent anti-TB drug-induced liver damage by downregulating the protein expression of HMGB 1 and RAGE in liver tissue and inhibiting the secretion of inflammatory factors. Orazamide can be used in research on hepatitis and liver ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Investigate mechanisms of toxicity for preclinical drug candidates to help decrease clinical trial safety failures. Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. ...
Manufactured by:Lumencor based inBeaverton, OREGON (USA)
Utilizing a dual-laser optical system, the VOLTA Scanner provides simultaneous stimulation and detection, ideal for kinetic assays of cellular activity. A typical application involves pharmacological safety profiling, such as detecting drug-induced QT prolongation using voltage-sensitive dyes that reveal changes in transmembrane voltage with 0.1 msec resolution. ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
The human lung is a key organ for multiple therapeutic endpoints, as well as a system that must be evaluated for potential drug-induced toxicities to ensure safety. Modeling the complex interplay of respiratory and vascular components through a reductionist approach has proven to be exceedingly difficult as significant differences exist between preclinical ...
Manufactured by:Vacumetrics Inc based inVentura, CALIFORNIA (USA)
Model "TurboAire Challenger" A cold air generator for cold air challenge testing. The TurboAire Challenger is a cost effective substitute for drug induced bronchospasm. Since no drugs or chemicals are administered, the patient risk is lower. The patient needs to be monitored for only one-half hour following the conclusion of the exposure to cold ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s nuclear receptor activation kits are all-inclusive cell-based assay systems. The kits incorporate mycoplasm-free, stably-transfected cells derived from hepatoma cell lines that have been treated with a cell-arrest agent to prevent further proliferation. Exposure to the cell-arrest agent ensures that the cells in the kits can only be used for a single 96 well assay. Each kit ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Profiling and screening of your compounds with a high throughput barrier integrity assay on our established Caco-2 intestinal model. OrganoServices are available for multiple assays to allow compound profiling and/or screening in human-relevant, complex 3D tissue models. When developing new drugs, it is critical to understand the permeability, absorption, and transport mechanisms in relevant ...
Manufactured by:Fiterman Pharma based inLasi, ROMANIA
The natural solution to fight against ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Colon Caco-2 offers 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused Caco-2 tubule. OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Blood Vessel HUVEC comprises 38 ready-to-use HUVEC tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Angiogenesis HUVEC comprises 64 HUVEC tubules ready-to-sprout. The product is based on the OrganoPlate® 3-lane 64 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Angiogenesis ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Fail early, fail fast! Assess Risk of Liver Injury Due to Compound Exposure with 3D InSight. 3D InSight Human Liver Microtissues are pharma-validated, preclinical co-culture liver models for toxicology testing that have been shown to achieve 2X higher sensitivity for DILI prediction compared to traditional 2D PHH. These advanced 3D liver models, which combine multi-donor diversity with ...
Manufactured by:Siemens Healthcare GmbH based inErlangen, GERMANY
The PFA-100® System measures the complex process of primary hemostasis and aids in the rapid detection of platelet dysfunction. It is the first commercially available in vitro testing system to incorporate high-shear flow in which the process of platelet adhesion and aggregation following a vascular injury is simulated ...
Manufactured by:Immunodiagnostic Systems Holdings PLC based inBoldon Colliery, UNITED KINGDOM
i-Tracker anti-Adalimumab is an automated assay intended for the quantitative measurement of anti-Adalimumab antibodies (anti-drug antibodies: ADAb) in human serum or plasma ...