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Liver Cells Equipment & Supplies In Usa
62 equipment items found
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Primary animal hepatocytes and subcellular liver fractions (Microsomes, Cytosol and S9 fraction) are model systems often used for a variety of in vitro screenings and analyses prior to clinical studies in human and animal health as well as environmental toxicology. Hepatocytes in suspension are preferable for short-term studies whereas plated hepatocytes are more useful for long-term ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Use filters on the table to find the best lot for your needs. Use the "export option" in the top right corner to export data (it can be exported table by table (excel) or all together (PDF, ...
Manufactured by:The Electrospinning Company Ltd. based inDidcot, UNITED KINGDOM
Images taken using a Nikon Eclispe C1 confocal microscope. HepG2 liver cells were grown for 21 days in the Mimetix scaffold. Cells are stained with DAPI and actin; fibres are electrospun together with Rhodamine 6G (a and b). Cancer cells form a 3D network inside the scaffold (c), use the fibres to support themselves (d) and ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
Myrcludex B is an experimental drug for the treatment of hepatitis B and D. The hepatitis B virus uses its surface lipopeptide pre-S1 for docking to mature liver cells via their sodium/bile acid cotransporter (NTCP) and subsequently entering the cells. Myrcludex B is a synthetic N-acylated pre-S1 that can also dock to NTCP, blocking the virus's ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
The liver contains two distinct endothelial cell types: vascular (LEC) and sinusoidal (LSEC). Liver Endothelial Cells (LEC) are highly specialized endothelial cells representing the interface between blood cells and the rest of liver cells. In fact, they ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
The limited availability of human hepatocytes makes cryopreservation a good option to provide researchers with a sufficient amount of viable liver ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole ...
by:Ionpath, Inc. based inMenlo Park, CALIFORNIA (USA)
Background:Arginase-1 is expressed by liver cells, myeloid-derived suppressor cells (MDSCs), macrophages, and neutrophils. In mammals, there are three enzymes that metabolise arginine: two arginase isoforms (ARG1, ARG2) and inducible nitric oxide synthase (iNOS). Arginase-1 catalyzes the breakdown of L-arginine into L-ornithine and urea as the ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver ...
Manufactured by:Sana Biotechnology based inSeattle, WASHINGTON (USA)
Liver-related genetic disorders: Ornithine transcarbamylase deficiency ...
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
Combining class I and class II engineering to create Universal Donor Cells (UDCs) that are appropriate for developing numerous differentiated cell ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic stellate cells (HSC) are also known as perisinusoidal cells and they are located in the space of disses. These cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in liver hepatocytes. Available as an ...
Manufactured by:Allium Ltd based in, ISRAEL
The bile ducts that emerge from the liver, their small size make them vulnerable to various pathological processes that interrupt their structure and ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Fail early, fail fast! Assess Risk of Liver Injury Due to Compound Exposure with 3D InSight. 3D InSight Human Liver Microtissues are pharma-validated, preclinical co-culture liver models for toxicology testing that have been shown to achieve 2X higher sensitivity for DILI prediction compared to traditional 2D PHH. These advanced 3D liver models, which combine multi-donor diversity with ...
Manufactured by:Protara Therapeutics, Inc. based inNew York, NEW YORK (USA)
IV choline chloride is an investigational, intravenous (IV) phospholipid substrate replacement therapy initially in development for patients receiving parenteral nutrition (PN) who have intestinal failure-associated liver disease (IFALD). Choline is a known important substrate for phospholipids that are critical for healthy liver function. Because PN patients cannot sufficiently absorb ...
Manufactured by:Ascelia Pharma AB based inMalmö, SWEDEN
Mangoral is a novel oral imaging agent in development for use in MR-imaging of the liver. Mangoral aims to improve the detection and visualization of focal liver lesions (including liver metastases and primary tumors) in patients with severe kidney impairment. Mangoral is currently in Phase 3 development including the registration-enabling study, ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
The current standard of care for autoimmune diseases is broad immunosuppression, which is associated with side effects and leaves patients vulnerable to serious infection and maligancies. Our approach to autoimmune disease is designed to restore natural self-tolerance by administering ImmTOR with nanoparticles-encapsulated self-antigens and avoid the need for chronic and systemic immune ...